Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   I5V48_RS03805 Genome accession   NZ_CP065430
Coordinates   778669..779373 (+) Length   234 a.a.
NCBI ID   WP_004298854.1    Uniprot ID   A0A0K2E6P6
Organism   Streptococcus suis strain YZDH1     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 773669..784373
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I5V48_RS03785 (I5V48_03785) - 775477..776136 (-) 660 WP_014637676.1 amino acid ABC transporter permease -
  I5V48_RS03790 (I5V48_03790) - 776151..776849 (-) 699 WP_004298848.1 amino acid ABC transporter permease -
  I5V48_RS03795 (I5V48_03795) - 776864..777703 (-) 840 WP_105130430.1 transporter substrate-binding domain-containing protein -
  I5V48_RS03800 (I5V48_03800) - 777714..778475 (-) 762 WP_105130429.1 amino acid ABC transporter ATP-binding protein -
  I5V48_RS03805 (I5V48_03805) micA 778669..779373 (+) 705 WP_004298854.1 response regulator YycF Regulator
  I5V48_RS03810 (I5V48_03810) micB 779366..780715 (+) 1350 WP_105152095.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I5V48_RS03815 (I5V48_03815) vicX 780722..781525 (+) 804 WP_044687053.1 MBL fold metallo-hydrolase Regulator
  I5V48_RS03820 (I5V48_03820) vga(F) 782055..783440 (+) 1386 WP_197315133.1 ABC-F type ribosomal protection protein Vga(F) -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26781.77 Da        Isoelectric Point: 4.8957

>NTDB_id=509515 I5V48_RS03805 WP_004298854.1 778669..779373(+) (micA) [Streptococcus suis strain YZDH1]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=509515 I5V48_RS03805 WP_004298854.1 778669..779373(+) (micA) [Streptococcus suis strain YZDH1]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACTCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTGTTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAGGTCGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATAGGGGCGGATGATTATGTGACCAAACCTTTCTCTAATCGCGA
ATTGCAGGCGCGCGTTAAGGCCCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGTTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAGCACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATACAC
CAAGCCGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K2E6P6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

99.573

0.816
  vicR Streptococcus mutans UA159

80.426

100

0.808
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376