Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   MYY_RS06400 Genome accession   NC_017769
Coordinates   1229410..1230060 (-) Length   216 a.a.
NCBI ID   WP_000387336.1    Uniprot ID   -
Organism   Streptococcus pneumoniae ST556     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1224410..1235060
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MYY_RS06385 (MYY_1246) - 1225012..1226196 (-) 1185 WP_000655961.1 membrane protein -
  MYY_RS06390 (MYY_1247) - 1226200..1226787 (-) 588 WP_000939881.1 ATP-binding cassette domain-containing protein -
  MYY_RS13660 (MYY_02935) - 1226820..1227037 (-) 218 Protein_1242 hypothetical protein -
  MYY_RS06395 (MYY_1248) comEC/celB 1227186..1229426 (-) 2241 WP_000942405.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  MYY_RS06400 (MYY_1249) comEA/celA/cilE 1229410..1230060 (-) 651 WP_000387336.1 ComEA family DNA-binding protein Machinery gene
  MYY_RS06405 (MYY_1250) - 1230128..1230697 (-) 570 WP_000443774.1 GNAT family N-acetyltransferase -
  MYY_RS13325 ald 1230874..1231985 (+) 1112 Protein_1246 alanine dehydrogenase -
  MYY_RS06425 (MYY_1254) - 1232286..1232612 (-) 327 Protein_1247 TfoX/Sxy family protein -
  MYY_RS06430 (MYY_1255) - 1232615..1233115 (-) 501 WP_000566986.1 GNAT family N-acetyltransferase -
  MYY_RS06435 (MYY_1257) - 1233308..1234276 (-) 969 WP_000658198.1 PhoH family protein -
  MYY_RS06440 (MYY_1258) - 1234362..1234577 (-) 216 WP_001232081.1 YozE family protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23189.54 Da        Isoelectric Point: 5.5171

>NTDB_id=50817 MYY_RS06400 WP_000387336.1 1229410..1230060(-) (comEA/celA/cilE) [Streptococcus pneumoniae ST556]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=50817 MYY_RS06400 WP_000387336.1 1229410..1230060(-) (comEA/celA/cilE) [Streptococcus pneumoniae ST556]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTAAAGGAAACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-126)

Helix-hairpin-helix motif (HHH_3)

(151-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae D39

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae R6

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

97.222

100

0.972
  comEA/celA/cilE Streptococcus mitis NCTC 12261

95.833

100

0.958
  comEA/celA/cilE Streptococcus mitis SK321

91.204

100

0.912
  comEA Lactococcus lactis subsp. cremoris KW2

43.612

100

0.458
  comEA Bacillus subtilis subsp. subtilis str. 168

41.579

87.963

0.366
  comEA Latilactobacillus sakei subsp. sakei 23K

33.476

100

0.361

Multiple sequence alignment