Detailed information
Bioinformatically predicted
Overview
| Name | prx | Type | Regulator |
| Locus tag | I2439_RS04840 | Genome accession | NZ_CP065191 |
| Coordinates | 1013169..1013357 (+) | Length | 62 a.a. |
| NCBI ID | WP_043983595.1 | Uniprot ID | - |
| Organism | Streptococcus equi subsp. zooepidemicus strain SEZ46 | ||
| Function | Inhibit ComR activation (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 976858..1015401 | 1013169..1013357 | within | 0 |
Gene organization within MGE regions
Location: 976858..1015401
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I2439_RS04580 (HIEAAJJG_00920) | thiI | 976858..978072 (+) | 1215 | WP_196820046.1 | tRNA uracil 4-sulfurtransferase ThiI | - |
| I2439_RS04585 (HIEAAJJG_00921) | - | 978194..978451 (-) | 258 | WP_231148175.1 | hypothetical protein | - |
| I2439_RS04590 (HIEAAJJG_00922) | - | 978848..979189 (-) | 342 | WP_196820047.1 | hypothetical protein | - |
| I2439_RS04595 (HIEAAJJG_00923) | - | 979748..980836 (-) | 1089 | WP_165619599.1 | site-specific integrase | - |
| I2439_RS04600 (HIEAAJJG_00924) | - | 980958..981632 (-) | 675 | WP_154803906.1 | NYN domain-containing protein | - |
| I2439_RS04605 (HIEAAJJG_00925) | - | 981847..982614 (-) | 768 | WP_165619598.1 | S24 family peptidase | - |
| I2439_RS04610 (HIEAAJJG_00927) | - | 983003..983161 (+) | 159 | WP_003056201.1 | hypothetical protein | - |
| I2439_RS04615 (HIEAAJJG_00928) | - | 983198..983410 (+) | 213 | WP_165619597.1 | hypothetical protein | - |
| I2439_RS04620 (HIEAAJJG_00929) | - | 983369..983914 (-) | 546 | WP_196820048.1 | hypothetical protein | - |
| I2439_RS04625 (HIEAAJJG_00930) | - | 983967..984173 (+) | 207 | WP_001157159.1 | helix-turn-helix transcriptional regulator | - |
| I2439_RS04630 (HIEAAJJG_00931) | - | 984213..984941 (+) | 729 | WP_165619573.1 | phage antirepressor KilAC domain-containing protein | - |
| I2439_RS04635 (HIEAAJJG_00933) | - | 985157..985447 (+) | 291 | WP_037578536.1 | MerR family transcriptional regulator | - |
| I2439_RS04640 (HIEAAJJG_00934) | - | 985593..986405 (+) | 813 | WP_050316935.1 | phage replisome organizer N-terminal domain-containing protein | - |
| I2439_RS04645 (HIEAAJJG_00935) | - | 986392..987174 (+) | 783 | WP_043983621.1 | ATP-binding protein | - |
| I2439_RS04650 (HIEAAJJG_00937) | - | 987311..987523 (+) | 213 | WP_043983620.1 | hypothetical protein | - |
| I2439_RS04655 (HIEAAJJG_00938) | - | 987587..987976 (+) | 390 | WP_111678017.1 | YopX family protein | - |
| I2439_RS04660 (HIEAAJJG_00939) | - | 988018..988317 (+) | 300 | WP_111678836.1 | VVA0879 family protein | - |
| I2439_RS04665 (HIEAAJJG_00940) | - | 988314..988514 (+) | 201 | WP_043983617.1 | hypothetical protein | - |
| I2439_RS04670 (HIEAAJJG_00941) | - | 988507..988734 (+) | 228 | WP_043983616.1 | membrane protein | - |
| I2439_RS04675 (HIEAAJJG_00942) | - | 988738..989223 (+) | 486 | WP_043983615.1 | class I SAM-dependent methyltransferase | - |
| I2439_RS04680 (HIEAAJJG_00943) | - | 989220..989978 (+) | 759 | WP_043983614.1 | DNA methyltransferase | - |
| I2439_RS04685 (HIEAAJJG_00944) | - | 989975..990193 (+) | 219 | WP_043983613.1 | hypothetical protein | - |
| I2439_RS04690 (HIEAAJJG_00945) | - | 990193..990624 (+) | 432 | WP_043983612.1 | ArpU family phage packaging/lysis transcriptional regulator | - |
| I2439_RS04695 (HIEAAJJG_00946) | - | 990762..991328 (+) | 567 | WP_111678019.1 | tyrosine-type recombinase/integrase | - |
| I2439_RS04700 (HIEAAJJG_00947) | - | 991492..991830 (+) | 339 | WP_043983611.1 | HNH endonuclease signature motif containing protein | - |
| I2439_RS04705 (HIEAAJJG_00948) | - | 991967..993229 (+) | 1263 | WP_196820049.1 | hypothetical protein | - |
| I2439_RS04710 (HIEAAJJG_00949) | - | 993222..994619 (+) | 1398 | WP_111690079.1 | hypothetical protein | - |
| I2439_RS04715 (HIEAAJJG_00950) | - | 994609..994902 (+) | 294 | WP_043983608.1 | hypothetical protein | - |
| I2439_RS04720 (HIEAAJJG_00951) | - | 994956..995180 (+) | 225 | WP_043983607.1 | hypothetical protein | - |
| I2439_RS04725 (HIEAAJJG_00952) | - | 995182..995439 (+) | 258 | WP_043983606.1 | DUF6275 family protein | - |
| I2439_RS04730 (HIEAAJJG_00953) | - | 995532..996947 (+) | 1416 | WP_111690080.1 | terminase | - |
| I2439_RS04735 (HIEAAJJG_00954) | - | 997022..997477 (+) | 456 | WP_037578498.1 | phage scaffold protein | - |
| I2439_RS04740 (HIEAAJJG_00955) | - | 997481..998371 (+) | 891 | WP_043053013.1 | phage major capsid protein | - |
| I2439_RS04745 (HIEAAJJG_00956) | - | 998374..998586 (+) | 213 | WP_043983605.1 | HeH/LEM domain-containing protein | - |
| I2439_RS04750 (HIEAAJJG_00957) | - | 998637..999035 (+) | 399 | WP_111690081.1 | phage Gp19/Gp15/Gp42 family protein | - |
| I2439_RS04755 (HIEAAJJG_00958) | - | 999022..999360 (+) | 339 | WP_111690082.1 | hypothetical protein | - |
| I2439_RS04760 (HIEAAJJG_00959) | - | 999353..999589 (+) | 237 | WP_043983604.1 | hypothetical protein | - |
| I2439_RS04765 (HIEAAJJG_00960) | - | 999590..999925 (+) | 336 | WP_043053018.1 | hypothetical protein | - |
| I2439_RS04770 (HIEAAJJG_00961) | - | 999942..1000523 (+) | 582 | WP_043983603.1 | hypothetical protein | - |
| I2439_RS04775 (HIEAAJJG_00962) | - | 1000534..1000797 (+) | 264 | WP_043983602.1 | hypothetical protein | - |
| I2439_RS04780 (HIEAAJJG_00963) | - | 1000812..1001183 (+) | 372 | WP_043983601.1 | DUF5361 domain-containing protein | - |
| I2439_RS04785 (HIEAAJJG_00964) | - | 1001183..1003543 (+) | 2361 | WP_043983600.1 | hypothetical protein | - |
| I2439_RS04790 (HIEAAJJG_00965) | - | 1003540..1004235 (+) | 696 | WP_043983599.1 | hypothetical protein | - |
| I2439_RS04795 (HIEAAJJG_00966) | - | 1004232..1006178 (+) | 1947 | WP_111678028.1 | phage tail spike protein | - |
| I2439_RS04800 (HIEAAJJG_00967) | - | 1006178..1006861 (+) | 684 | WP_111678029.1 | collagen-like protein | - |
| I2439_RS04805 (HIEAAJJG_00968) | - | 1006863..1007480 (+) | 618 | WP_043983598.1 | hypothetical protein | - |
| I2439_RS04810 (HIEAAJJG_00969) | - | 1007490..1009355 (+) | 1866 | WP_196820050.1 | gp58-like family protein | - |
| I2439_RS04815 (HIEAAJJG_00970) | - | 1009369..1009554 (+) | 186 | WP_111678031.1 | hypothetical protein | - |
| I2439_RS04820 (HIEAAJJG_00971) | - | 1009557..1010171 (+) | 615 | WP_111678032.1 | DUF1366 domain-containing protein | - |
| I2439_RS04825 (HIEAAJJG_00972) | - | 1010182..1010553 (+) | 372 | WP_012678881.1 | phage holin family protein | - |
| I2439_RS04830 (HIEAAJJG_00974) | - | 1010669..1011865 (+) | 1197 | WP_043983596.1 | glucosaminidase domain-containing protein | - |
| I2439_RS04835 (HIEAAJJG_00975) | - | 1012246..1012821 (+) | 576 | WP_012679345.1 | phospholipase A2 SlaA | - |
| I2439_RS10365 (HIEAAJJG_00976) | - | 1012815..1013102 (+) | 288 | WP_011106694.1 | hypothetical protein | - |
| I2439_RS04840 (HIEAAJJG_00977) | prx | 1013169..1013357 (+) | 189 | WP_043983595.1 | Paratox | Regulator |
| I2439_RS04850 (HIEAAJJG_00979) | - | 1013949..1014560 (+) | 612 | WP_043025737.1 | TVP38/TMEM64 family protein | - |
| I2439_RS04855 (HIEAAJJG_00980) | - | 1014607..1015401 (-) | 795 | WP_196820051.1 | ABC transporter permease | - |
Sequence
Protein
Download Length: 62 a.a. Molecular weight: 7221.23 Da Isoelectric Point: 5.0079
>NTDB_id=507824 I2439_RS04840 WP_043983595.1 1013169..1013357(+) (prx) [Streptococcus equi subsp. zooepidemicus strain SEZ46]
MLTYDEFKQAIDHGYITGDTVAIVRKNGQIFDYVLPHESVRSWEVVTEERVEAVLKELHCIK
MLTYDEFKQAIDHGYITGDTVAIVRKNGQIFDYVLPHESVRSWEVVTEERVEAVLKELHCIK
Nucleotide
Download Length: 189 bp
>NTDB_id=507824 I2439_RS04840 WP_043983595.1 1013169..1013357(+) (prx) [Streptococcus equi subsp. zooepidemicus strain SEZ46]
GTGTTAACATACGACGAGTTTAAGCAGGCTATTGATCATGGTTATATCACAGGAGACACAGTAGCGATTGTGCGCAAAAA
CGGACAGATTTTTGATTATGTGTTGCCGCATGAGTCTGTGAGATCGTGGGAGGTTGTGACTGAAGAAAGAGTAGAAGCAG
TACTAAAAGAATTACACTGTATTAAATGA
GTGTTAACATACGACGAGTTTAAGCAGGCTATTGATCATGGTTATATCACAGGAGACACAGTAGCGATTGTGCGCAAAAA
CGGACAGATTTTTGATTATGTGTTGCCGCATGAGTCTGTGAGATCGTGGGAGGTTGTGACTGAAGAAAGAGTAGAAGCAG
TACTAAAAGAATTACACTGTATTAAATGA
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| prx | Streptococcus pyogenes MGAS315 |
82.759 |
93.548 |
0.774 |
| prx | Streptococcus pyogenes MGAS315 |
82.759 |
93.548 |
0.774 |
| prx | Streptococcus pyogenes MGAS8232 |
81.034 |
93.548 |
0.758 |
| prx | Streptococcus pyogenes MGAS315 |
74.576 |
95.161 |
0.71 |
| prx | Streptococcus pyogenes MGAS315 |
88.095 |
67.742 |
0.597 |
| prx | Streptococcus pyogenes MGAS315 |
85.714 |
67.742 |
0.581 |
| prx | Streptococcus pyogenes MGAS315 |
80.952 |
67.742 |
0.548 |