Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   I2436_RS06890 Genome accession   NZ_CP065060
Coordinates   1470704..1471414 (-) Length   236 a.a.
NCBI ID   WP_012515994.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ28     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1465704..1476414
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2436_RS06875 (GDAKBCAL_01379) - 1466150..1467664 (-) 1515 WP_206152715.1 helix-turn-helix domain-containing protein -
  I2436_RS06880 (GDAKBCAL_01380) vicX 1468546..1469355 (-) 810 WP_021320992.1 MBL fold metallo-hydrolase Regulator
  I2436_RS06885 (GDAKBCAL_01381) vicK 1469359..1470711 (-) 1353 WP_012677636.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I2436_RS06890 (GDAKBCAL_01382) vicR 1470704..1471414 (-) 711 WP_012515994.1 response regulator YycF Regulator
  I2436_RS06895 (GDAKBCAL_01383) - 1471623..1472639 (-) 1017 WP_206153255.1 DUF3114 domain-containing protein -
  I2436_RS06900 (GDAKBCAL_01384) - 1472685..1473947 (-) 1263 WP_206152716.1 AMP-binding protein -
  I2436_RS06905 (GDAKBCAL_01385) - 1473937..1475052 (-) 1116 WP_206152717.1 acetyl-CoA C-acyltransferase -
  I2436_RS06910 (GDAKBCAL_01386) - 1475049..1475588 (-) 540 WP_206152718.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 26981.84 Da        Isoelectric Point: 4.9038

>NTDB_id=506552 I2436_RS06890 WP_012515994.1 1470704..1471414(-) (vicR) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKAYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=506552 I2436_RS06890 WP_012515994.1 1470704..1471414(-) (vicR) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
ATGAAGAAAATACTGATTGTTGATGATGAAAAGCCGATTTCTGATATCATTAAATTTAATCTGACAAAGGAAGGCTATGA
TACGGTCACAGCATTTGATGGCAAAGAGGCCGTTGCAGTCTTTGAAGAGGAAAAGCCAGATTTGATTATTTTGGATTTGA
TGCTTCCTGAATTAGATGGCCTTGAGGTAGCCAAGGAAATCCGCAAGACCAGCCATATTCCTATCATCATGCTATCTGCT
AAGGATAGCGAATTTGATAAGGTGATTGGACTTGAAATAGGGGCTGATGATTATGTGACTAAGCCCTTTTCAAATCGTGA
GCTGCTGGCGCGTGTCAAGGCACATTTGCGTCGGACAGAGACTATTGAGACAGCAGTAGCCGAAGAAAATGCCTCCTCAG
GCTCTCAGGAGCTAACCATCGGCAATCTACAGATTTTACCAGATGCCTTTATCGCTAAAAAGCATGGTCAAGAGGTTGAG
CTGACCCATCGTGAGTTTGAATTGCTGCATCATCTGGCAAACCATATCGGACAGGTCATGACACGTGAGCATTTGCTTGA
GACCGTATGGGGCTACGATTATTTTGGCGATGTCCGAACCGTTGACGTTACTATCCGTCGCCTGCGCGAAAAAATAGAGG
ATACACCGAGTCGTCCAGAGTATATTTTGACAAGACGTGGTGTTGGGTACTACATGAAGGCTTATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

88.983

100

0.89
  micA Streptococcus pneumoniae Cp1015

78.112

98.729

0.771
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

38.034

99.153

0.377