Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   I2436_RS06885 Genome accession   NZ_CP065060
Coordinates   1469359..1470711 (-) Length   450 a.a.
NCBI ID   WP_012677636.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ28     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1464359..1475711
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2436_RS06870 (GDAKBCAL_01378) rnc 1465196..1465888 (-) 693 WP_037581642.1 ribonuclease III -
  I2436_RS06875 (GDAKBCAL_01379) - 1466150..1467664 (-) 1515 WP_206152715.1 helix-turn-helix domain-containing protein -
  I2436_RS06880 (GDAKBCAL_01380) vicX 1468546..1469355 (-) 810 WP_021320992.1 MBL fold metallo-hydrolase Regulator
  I2436_RS06885 (GDAKBCAL_01381) vicK 1469359..1470711 (-) 1353 WP_012677636.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I2436_RS06890 (GDAKBCAL_01382) vicR 1470704..1471414 (-) 711 WP_012515994.1 response regulator YycF Regulator
  I2436_RS06895 (GDAKBCAL_01383) - 1471623..1472639 (-) 1017 WP_206153255.1 DUF3114 domain-containing protein -
  I2436_RS06900 (GDAKBCAL_01384) - 1472685..1473947 (-) 1263 WP_206152716.1 AMP-binding protein -
  I2436_RS06905 (GDAKBCAL_01385) - 1473937..1475052 (-) 1116 WP_206152717.1 acetyl-CoA C-acyltransferase -
  I2436_RS06910 (GDAKBCAL_01386) - 1475049..1475588 (-) 540 WP_206152718.1 hypothetical protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51541.94 Da        Isoelectric Point: 5.5557

>NTDB_id=506551 I2436_RS06885 WP_012677636.1 1469359..1470711(-) (vicK) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLMSHKIRDLINGRYTDTINEKADIELMELSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVTQLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITS
IWLEIDNDKMTQVIENILNNAIKYSPDGGKIIVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=506551 I2436_RS06885 WP_012677636.1 1469359..1470711(-) (vicK) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
ATGACTAAGGACATCATTGGAAACCTTTCTGCATTTGAGCTAGCCATACTCTTATTGCTTGTTTTTGTTGCTTTTTATTT
CATTCATTTAGCCATTCGTGATTATCGCAATGCTCGGATCATTCGTCTGATGAGCCATAAGATAAGAGATTTGATCAATG
GTCGCTATACTGATACGATCAATGAAAAGGCTGATATTGAATTGATGGAGCTGTCTGAGCAGCTCAACGACCTATCAGAT
GTTTTTCGTCTGACCCATGAAAACCTTGCCCAAGAGAAAAATCGTCTTGCTAGTATTTTGGCTTATATGACAGATGGGGT
CCTTGCGACCAATCGTTCCGGCAAGATTATCATGATTAATGAGACTGCTCAAAAGCAGCTCAATTTAAATCGTGAGCAGG
CGCTGGAAAAAAACATTACAGATTTATTAGACAGTGACTCACCTTACACCTACCGAGAGCTGGTCTCAAAAACACCGATT
GTGACCTTAAATCGTCGTAATGACACAGGAGAGTTTGTTTCGCTGCGGCTGCGTTTTGCGCTTAATAGGCGAGAGAGCGG
CTTTATTTCAGGTCTAGTTGTTGTGCTTCATGACACGACTGAGCAGGAAAAGGAGGAGCGTGAGCGCAGACTCTTTGTCT
CAAATGTTAGCCATGAGCTTCGCACACCTTTGACCTCTGTCAAGTCATACCTAGAGGCTCTAGATGAGGGCGCGCTAAAG
GAGGACATAGCCCCAAGCTTTATAAAGGTCTCACTAGACGAAACCAATCGCATGATGCGCATGATTTCAGATTTGCTCAA
TCTATCAAGAATTGATAATCATGTGACACAGCTGTCTGTTGAAATGACCAACTTTACAGCCTTTATGACCTCTATCTTAA
ACCGCTTTGATTTGGTGAAAAATCAGCACACAAGCACAGGAAAATCCTATGAAATTGTCAGAGATTACCCTATCACCTCT
ATTTGGCTAGAAATTGATAACGATAAAATGACGCAGGTCATTGAAAATATTTTAAACAATGCCATCAAATATTCACCTGA
TGGTGGGAAAATTATCGTAAACATGAAAACAACAGATACCCAGCTAATCATTTCGATTTCTGATGAGGGTTTGGGCATTC
CAAAAAAGGACCTGCCTTTGATTTTTGACCGTTTTTACCGAGTGGATAAGGCTAGAAGTCGGGCGCAGGGGGGTACCGGC
TTAGGGCTGGCTATTGCCAAAGAAATTATCAAGCAGCACCGAGGCTTTATCTGGGCTAAGAGTGACTATGGCAAGGGGTC
AACCTTTACCATTGTGTTACCTTACGAAAAGGATGCTGCTATCTATGATGAATGGGAGGATGATATTGATTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92

0.678
  micB Streptococcus pneumoniae Cp1015

66.824

94.444

0.631