Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexA   Type   Machinery gene
Locus tag   I6L84_RS00625 Genome accession   NZ_CP077224
Coordinates   111095..113638 (+) Length   847 a.a.
NCBI ID   WP_060554251.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS 1454     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 106095..118638
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L84_RS00610 (I6L84_00610) - 107498..108433 (+) 936 WP_060554253.1 YitT family protein -
  I6L84_RS00615 (I6L84_00615) argS 108662..110350 (-) 1689 WP_060554252.1 arginine--tRNA ligase -
  I6L84_RS00620 (I6L84_00620) argR 110479..110916 (+) 438 WP_008809983.1 arginine repressor -
  I6L84_RS00625 (I6L84_00625) hexA 111095..113638 (+) 2544 WP_060554251.1 DNA mismatch repair protein MutS Machinery gene
  I6L84_RS00630 (I6L84_00630) - 113755..114528 (+) 774 WP_248842273.1 zinc ribbon domain-containing protein -
  I6L84_RS00635 (I6L84_00635) - 114572..115879 (+) 1308 WP_060554250.1 SPFH domain-containing protein -
  I6L84_RS00640 (I6L84_00640) - 115912..116382 (-) 471 WP_060554249.1 DUF3021 family protein -
  I6L84_RS00645 (I6L84_00645) brsR 116379..116819 (-) 441 WP_060554248.1 LytTR family DNA-binding domain-containing protein Regulator

Sequence

Protein


Download         Length: 847 a.a.        Molecular weight: 95203.37 Da        Isoelectric Point: 4.8210

>NTDB_id=505752 I6L84_RS00625 WP_060554251.1 111095..113638(+) (hexA) [Streptococcus gordonii strain FDAARGOS 1454]
MATEKISPGMQQYLDIKKDYQDAFLLFRMGDFYELFYEDAVNAAQILEIALTSRNKNSENPIPMAGVPYHSAQQYIDVLI
ESGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPAGENNFLVALDRQEQAYGLAYMDLATGEFQVTSLSDFDQ
ACGEIRNLRAREVVVGYCLSEDEQQVLSKQMNLLLSEVEEAMEDVQLLGDELSSLEKQTAGKLLAYVFQTQMRELSHLKK
VHHYEIKDFLQMDYATKTSLDLTENARTGKKHGSLFWLMDETKTAMGGRLLRSWIQHPLIDKGRIIKRQDVVQVFLDYFF
ERSDLADSLKGVYDIERLVSRVSFGKTNPKDLLQLSSTLSHVPQIRSILETIESPALESLVARLDAIPELENLISSAIDP
DAPQVITEGNIIRTGFDETLDQYRLVMREGTSWIADIEAKEREASGITNLKIDYNKKDGYYFHVTNSQLGNVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFMRIREEVGKYIQRLQALAQTLATVDVLQSFAVVAESQHLVRPSFT
SSRSLQIKKGRHAVVEKVMGAQSYIPNSIELDQGTDIQLITGPNMSGKSTYMRQLAMIVIMAQMGSYVPAEVASLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANRAIRQASDHSLILFDELGRGTATYDGMALAQAIIEYIHDRTKAKTLFATHYHEL
TDLSSSLTRLENVHVATLEKDGQVTFLHKIEAGPADKSYGIHVAKIAGLPTDLLRRADAILTDLENQEKRETSLSVSRMD
SQKVSEQMSLFEEETEHPALAELRDLDIYNMTPLEVMAAVAELKKKL

Nucleotide


Download         Length: 2544 bp        

>NTDB_id=505752 I6L84_RS00625 WP_060554251.1 111095..113638(+) (hexA) [Streptococcus gordonii strain FDAARGOS 1454]
ATGGCAACAGAAAAAATATCGCCAGGTATGCAGCAGTACTTGGATATTAAAAAAGACTATCAGGACGCCTTCCTGCTGTT
TCGTATGGGTGATTTCTATGAGTTGTTTTACGAGGATGCTGTTAATGCGGCACAGATTCTCGAGATTGCCCTGACTAGCC
GTAATAAGAATTCAGAAAATCCCATTCCAATGGCGGGTGTACCTTATCACTCTGCCCAGCAATATATTGATGTTTTGATT
GAGTCTGGTTATAAGGTTGCCATTGCAGAGCAGATGGAAGATCCTAAACAGGCCGTGGGGGTGGTCAAACGCGAGGTGGT
CCAGGTTATTACGCCGGGTACGGTAGTGGATTCTAGTAAGCCAGCCGGAGAAAATAACTTTTTGGTTGCTTTGGATAGGC
AGGAGCAAGCTTATGGCTTGGCCTATATGGATCTGGCTACGGGAGAATTTCAGGTGACCAGTCTATCAGATTTTGACCAA
GCTTGTGGAGAAATTCGAAATCTCCGAGCTCGGGAAGTAGTCGTAGGTTATTGCTTGTCAGAAGATGAGCAGCAGGTTTT
GTCAAAACAAATGAATCTACTCCTGTCAGAAGTCGAGGAAGCAATGGAGGACGTTCAGCTCTTAGGAGATGAGTTGTCAT
CTTTAGAAAAGCAGACGGCAGGGAAGCTTCTGGCTTATGTTTTTCAGACGCAGATGCGGGAGCTCAGCCATCTCAAAAAG
GTCCATCATTATGAGATAAAAGATTTTCTTCAGATGGACTATGCGACAAAGACCAGTCTGGACTTGACTGAAAATGCCCG
GACGGGCAAGAAGCATGGTAGTCTTTTTTGGCTCATGGATGAAACAAAAACAGCCATGGGAGGACGCTTGCTTCGTTCTT
GGATCCAGCATCCCTTGATTGATAAGGGACGAATCATCAAGCGTCAAGATGTCGTTCAGGTCTTTCTGGATTATTTCTTT
GAGCGGAGTGATTTGGCAGATAGTCTCAAGGGCGTCTATGATATTGAACGCCTGGTAAGTCGTGTGTCATTTGGCAAGAC
CAATCCCAAGGACCTCCTGCAATTGTCTTCTACTTTGAGCCATGTTCCTCAGATTCGGTCAATTTTAGAAACGATTGAAA
GTCCAGCTCTGGAGAGTTTGGTGGCAAGGCTAGATGCGATTCCTGAGCTGGAAAATCTAATCAGCTCTGCTATTGACCCA
GATGCTCCACAAGTAATTACTGAGGGCAATATCATTCGAACTGGTTTTGACGAGACTTTGGACCAGTACCGTTTGGTCAT
GAGAGAGGGGACTAGCTGGATTGCGGACATTGAAGCCAAGGAGCGAGAGGCAAGTGGTATTACTAATCTGAAAATTGATT
ATAACAAGAAGGATGGTTACTATTTCCATGTCACCAATTCTCAACTAGGCAATGTCCCTAGCCATTTTTTCCGGAAAGCA
ACCTTGAAAAATTCTGAGCGTTTTGGTACGGAAGAGCTGGCGCGCATTGAAGGCGAGATGTTGGAGGCGCGTGAGAAGTC
TGCTAATCTGGAATATGAGATCTTCATGCGCATTCGTGAAGAGGTCGGAAAATATATTCAACGGCTACAAGCCTTAGCTC
AAACCCTAGCTACGGTCGATGTTTTACAGAGCTTTGCGGTTGTGGCTGAAAGTCAACACTTAGTCCGTCCAAGCTTTACA
AGCAGTCGTAGTTTGCAGATTAAAAAAGGCCGTCATGCGGTTGTCGAAAAAGTCATGGGAGCCCAAAGCTACATCCCAAA
TAGTATCGAGCTGGATCAAGGAACAGATATTCAGCTGATTACCGGACCAAATATGAGCGGGAAGTCAACCTACATGCGAC
AGCTAGCAATGATTGTCATCATGGCTCAAATGGGATCGTATGTACCAGCGGAAGTCGCCAGTCTTCCGATTTTCGATGCT
ATCTTTACACGAATAGGTGCGGCGGATGATTTAGTTTCTGGTCAATCGACCTTTATGGTGGAAATGATGGAGGCCAATCG
GGCCATTCGACAAGCAAGTGACCACTCTTTGATCCTTTTTGATGAACTGGGACGGGGGACTGCGACTTATGATGGGATGG
CTCTGGCGCAAGCAATTATTGAGTATATTCATGATCGTACCAAGGCCAAGACTCTTTTTGCAACCCATTATCATGAGTTG
ACAGACCTGTCAAGTAGCTTGACACGATTAGAAAACGTCCATGTGGCAACTCTAGAGAAAGATGGCCAAGTGACATTTTT
GCATAAGATTGAAGCAGGACCTGCTGACAAGTCCTATGGGATTCATGTTGCAAAAATTGCTGGCTTACCTACGGATTTGT
TAAGGCGAGCAGATGCGATTTTGACAGATTTGGAAAATCAAGAGAAAAGAGAGACTTCTCTTTCAGTGTCCAGAATGGAC
TCCCAAAAGGTGTCTGAGCAGATGTCACTTTTTGAAGAAGAAACGGAACATCCAGCCCTGGCTGAACTCCGAGACTTGGA
CATCTACAATATGACTCCCCTGGAAGTCATGGCGGCGGTAGCCGAGTTGAAGAAGAAGTTGTAA

Domains

Predicted by InterProScan.

MutS domain I (MutS_I)

(8-118)

MutS domain V (MutS_V)

(599-785)

MutS domain III (MutS_III)

(256-546)

MutS domain II (MutS_II)

(126-239)

MutS family domain IV (MutS_IV)

(415-505)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexA Streptococcus pneumoniae R6

77.922

100

0.779
  mutS Pseudomonas stutzeri strain ATCC 17587

36.775

100

0.374