Detailed information NTG0501052

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: IUJ46_RS00275
• Genome accession: NZ_CP064364
• Coordinates: 51551..52141 (+)
• Length: 196 a.a.
• NCBI ID: WP_002985850.1
• Uniprot ID: A0A9X8T4H8
• Organism: Streptococcus pyogenes strain PartK-Spyogenes-RM8376
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 46551..57141

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IUJ46_RS00260 (IUJ46_00255)	-	47363..48808 (-)	1446	WP_010921928.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
IUJ46_RS00265 (IUJ46_00260)	-	48896..50530 (+)	1635	WP_002985856.1	polysaccharide biosynthesis protein	-
IUJ46_RS00270 (IUJ46_00265)	upp	50698..51327 (+)	630	WP_002985854.1	uracil phosphoribosyltransferase	-
IUJ46_RS00275 (IUJ46_00270)	clpP	51551..52141 (+)	591	WP_002985850.1	ATP-dependent Clp protease proteolytic subunit	Regulator
IUJ46_RS00280 (IUJ46_00275)	-	52633..52908 (+)	276	WP_002985847.1	YlbG family protein	-
IUJ46_RS00285 (IUJ46_00280)	tmk	53157..53792 (+)	636	WP_010921930.1	dTMP kinase	-
IUJ46_RS00290 (IUJ46_00285)	-	53810..54685 (+)	876	WP_010921931.1	DNA polymerase III subunit delta'	-
IUJ46_RS00295 (IUJ46_00290)	-	54704..54943 (+)	240	WP_010921932.1	PSP1 C-terminal domain-containing protein	-
IUJ46_RS00300 (IUJ46_00295)	yabA	55348..55671 (+)	324	WP_002985838.1	DNA replication initiation control protein YabA	-
IUJ46_RS00305 (IUJ46_00300)	rsmI	55676..56539 (+)	864	WP_029714023.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
IUJ46_RS00310 (IUJ46_00305)	-	56566..56958 (+)	393	WP_002985833.1	DUF5684 domain-containing protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21648.88 Da
• Isoelectric Point: 5.2834

>NTDB_id=501052 IUJ46_RS00275 WP_002985850.1 51551..52141(+) (clpP) [Streptococcus pyogenes strain PartK-Spyogenes-RM8376]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK

Nucleotide

• Length: 591 bp

>NTDB_id=501052 IUJ46_RS00275 WP_002985850.1 51551..52141(+) (clpP) [Streptococcus pyogenes strain PartK-Spyogenes-RM8376]
ATGATTCCTGTTGTTATTGAACAAACTAGCCGTGGAGAACGTTCTTATGACATTTATTCACGTTTATTAAAAGACCGTAT
TATCATGTTAACAGGGCCTGTCGAAGACAACATGGCCAACTCTGTCATAGCGCAGCTCTTATTCCTTGACGCGCAAGACA
ACACTAAAGATATCTACCTATATGTCAACACACCAGGTGGCTCTGTCTCAGCAGGCTTGGCTATTGTCGATACCATGAAC
TTTATCAAGGCCGATGTGCAAACTATTGTCATGGGTATGGCAGCTTCTATGGGGACAGTCATTGCTTCATCAGGAACAAA
AGGCAAACGCTTTATGTTACCAAATGCAGAGTATATGATCCACCAGCCAATGGGTGGTACAGGTGGTGGCACGCAACAAA
CGGATATGGCTATCGCAGCAGAACATCTCTTAAAAACACGTCACCGTTTAGAAAAAATCTTAGCGCAAAATGCTGGAAAA
ACGATTAAACAAATCCATAAAGATGCTGAGCGTGATTATTGGATGAGTGCTGAAGAAACCTTGGCTTACGGTTTCATTGA
TGAAATCATGGAAAACAACGAACTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pyogenes MGAS315	100	100	1
clpP	Streptococcus pyogenes JRS4	100	100	1
clpP	Streptococcus mutans UA159	90.816	100	0.908
clpP	Streptococcus pneumoniae Rx1	90.769	99.49	0.903
clpP	Streptococcus pneumoniae D39	90.769	99.49	0.903
clpP	Streptococcus pneumoniae R6	90.769	99.49	0.903
clpP	Streptococcus pneumoniae TIGR4	90.769	99.49	0.903
clpP	Streptococcus thermophilus LMG 18311	89.796	100	0.898
clpP	Streptococcus thermophilus LMD-9	89.796	100	0.898
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	86.224	100	0.862
clpP	Lactococcus lactis subsp. cremoris KW2	85.714	100	0.857
clpP	Bacillus subtilis subsp. subtilis str. 168	57.143	100	0.571
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.995	98.469	0.561