Detailed information NTG0049796

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: SSUD12_RS07480
• Genome accession: NC_017621
• Coordinates: 1518142..1518732 (-)
• Length: 196 a.a.
• NCBI ID: WP_014638366.1
• Uniprot ID: A0A0Z8P1Q4
• Organism: Streptococcus suis D12
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1513142..1523732

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSUD12_RS07455 (SSUD12_1501)	-	1513640..1514404 (-)	765	WP_002937291.1	ABC transporter ATP-binding protein	-
SSUD12_RS07460 (SSUD12_1502)	-	1514404..1515351 (-)	948	WP_002937293.1	branched-chain amino acid ABC transporter permease	-
SSUD12_RS07465 (SSUD12_1503)	-	1515354..1516241 (-)	888	WP_014638363.1	branched-chain amino acid ABC transporter permease	-
SSUD12_RS07470 (SSUD12_1504)	-	1516442..1517611 (-)	1170	WP_014638364.1	ABC transporter substrate-binding protein	-
SSUD12_RS07475 (SSUD12_1505)	-	1517743..1518015 (-)	273	WP_014638365.1	YlbG family protein	-
SSUD12_RS07480 (SSUD12_1506)	clpP	1518142..1518732 (-)	591	WP_014638366.1	ATP-dependent Clp protease proteolytic subunit	Regulator
SSUD12_RS07485 (SSUD12_1507)	upp	1518849..1519478 (-)	630	WP_012027487.1	uracil phosphoribosyltransferase	-
SSUD12_RS07490 (SSUD12_1508)	-	1519558..1521174 (-)	1617	WP_014638367.1	glycoside hydrolase family 13 protein	-
SSUD12_RS07495 (SSUD12_1509)	gtfA	1521247..1522695 (-)	1449	WP_014638368.1	sucrose phosphorylase	-
SSUD12_RS07500 (SSUD12_1510)	-	1522765..1523595 (-)	831	WP_002937312.1	carbohydrate ABC transporter permease	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21508.76 Da
• Isoelectric Point: 5.7110

>NTDB_id=49796 SSUD12_RS07480 WP_014638366.1 1518142..1518732(-) (clpP) [Streptococcus suis D12]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDPTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGTAASMGTIIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNKLEKILADNSGK
TVKQIHKDAERDYWMTAEETLAYGFIDQIMDNTKVK

Nucleotide

• Length: 591 bp

>NTDB_id=49796 SSUD12_RS07480 WP_014638366.1 1518142..1518732(-) (clpP) [Streptococcus suis D12]
ATGATTCCAGTAGTTATTGAACAAACTAGCCGTGGTGAGCGTTCTTATGATATTTACTCACGCCTTTTGAAAGACCGTAT
TATCATGTTGACAGGACCAGTTGAGGACAACATGGCAAACTCTATCATTGCACAATTGCTTTTCCTTGATGCCCAAGACC
CTACAAAGGATATTTACCTCTATGTTAATACGCCAGGAGGATCGGTGTCAGCAGGTCTTGCTATTGTAGACACGATGAAT
TTCATTAAAGCTGATGTTCAAACCATCGTTATGGGAACAGCTGCGAGCATGGGAACCATCATTGCATCAAGCGGTGCCAA
GGGCAAACGTTTCATGTTGCCAAATGCAGAGTACATGATTCACCAGCCAATGGGTGGAACAGGTGGCGGTACACAGCAAA
CGGATATGGCCATTGCAGCGGAACACTTGCTTAAAACCCGTAACAAATTAGAAAAAATCTTGGCTGACAATTCAGGAAAA
ACAGTGAAACAAATCCACAAGGATGCAGAACGCGATTACTGGATGACAGCAGAAGAAACACTAGCTTACGGATTTATCGA
TCAAATTATGGACAATACAAAAGTGAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A0Z8P1Q4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pyogenes JRS4	91.837	100	0.918
clpP	Streptococcus pyogenes MGAS315	91.837	100	0.918
clpP	Streptococcus mutans UA159	90.306	100	0.903
clpP	Streptococcus pneumoniae R6	88.265	100	0.883
clpP	Streptococcus pneumoniae Rx1	88.265	100	0.883
clpP	Streptococcus pneumoniae D39	88.265	100	0.883
clpP	Streptococcus pneumoniae TIGR4	88.265	100	0.883
clpP	Streptococcus thermophilus LMG 18311	88.265	100	0.883
clpP	Streptococcus thermophilus LMD-9	88.265	100	0.883
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	84.184	100	0.842
clpP	Lactococcus lactis subsp. cremoris KW2	83.673	100	0.837
clpP	Bacillus subtilis subsp. subtilis str. 168	57.653	100	0.577
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.031	98.469	0.571