Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   SPYALAB49_RS05685 Genome accession   NC_017596
Coordinates   1131589..1131771 (-) Length   60 a.a.
NCBI ID   WP_014635572.1    Uniprot ID   A0A8B6J386
Organism   Streptococcus pyogenes Alab49     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context


Location: 1126589..1136771
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYALAB49_RS05670 (SPYALAB49_001162) - 1127027..1127722 (-) 696 WP_002983928.1 phosphoglycerate mutase -
  SPYALAB49_RS05675 (SPYALAB49_001164) - 1127961..1128896 (+) 936 WP_002989136.1 dihydroorotate oxidase -
  SPYALAB49_RS05680 (SPYALAB49_001166) - 1129196..1131058 (-) 1863 WP_014635571.1 heavy metal translocating P-type ATPase -
  SPYALAB49_RS05685 (SPYALAB49_001167) prx 1131589..1131771 (-) 183 WP_014635572.1 hypothetical protein Regulator
  SPYALAB49_RS05690 (SPYALAB49_001168) mf2 1132011..1132769 (+) 759 WP_014635573.1 DNase Mf2 -
  SPYALAB49_RS05695 (SPYALAB49_001169) speC 1132880..1133587 (+) 708 WP_002985327.1 streptococcal pyrogenic exotoxin SpeC -
  SPYALAB49_RS05700 (SPYALAB49_001170) - 1133656..1134873 (-) 1218 WP_014635574.1 peptidoglycan amidohydrolase family protein -
  SPYALAB49_RS05710 (SPYALAB49_001171) - 1134992..1135219 (-) 228 WP_003058873.1 phage holin -
  SPYALAB49_RS05715 (SPYALAB49_001172) - 1135216..1135488 (-) 273 WP_011017397.1 hypothetical protein -
  SPYALAB49_RS05720 (SPYALAB49_001173) - 1135500..1136132 (-) 633 WP_014635575.1 hypothetical protein -
  SPYALAB49_RS05725 (SPYALAB49_001174) - 1136135..1136563 (-) 429 WP_011528780.1 DUF1617 family protein -

Sequence


Protein


Download         Length: 60 a.a.        Molecular weight: 7067.01 Da        Isoelectric Point: 4.1079

>NTDB_id=49540 SPYALAB49_RS05685 WP_014635572.1 1131589..1131771(-) (prx) [Streptococcus pyogenes Alab49]
MLTYDEFKQAIDNGYITGDTVMIVRKNGQIFDYVLPNEKIRDWEVVTDEKVEEVLVELSR

Nucleotide


Download         Length: 183 bp        

>NTDB_id=49540 SPYALAB49_RS05685 WP_014635572.1 1131589..1131771(-) (prx) [Streptococcus pyogenes Alab49]
ATGCTAACATACGACGAATTTAAGCAAGCAATTGACAACGGATATATCACAGGAGACACAGTTATGATCGTGCGTAAAAA
CGGACAGATTTTTGATTATGTTTTGCCGAATGAGAAGATAAGAGATTGGGAGGTTGTGACAGACGAAAAAGTGGAAGAGG
TGCTGGTGGAGCTTTCGAGATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

90

100

0.9

  prx Streptococcus pyogenes MGAS8232

85

100

0.85

  prx Streptococcus pyogenes MGAS315

80

100

0.8

  prx Streptococcus pyogenes MGAS315

73.333

100

0.733

  prx Streptococcus pyogenes MGAS315

90.244

68.333

0.617

  prx Streptococcus pyogenes MGAS315

85.714

70

0.6

  prx Streptococcus pyogenes MGAS315

78.571

70

0.55


Multiple sequence alignment