Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   SALIVA_RS04835 Genome accession   NC_017595
Coordinates   995541..996248 (+) Length   235 a.a.
NCBI ID   WP_014634412.1    Uniprot ID   -
Organism   Streptococcus salivarius JIM8777     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 990541..1001248
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SALIVA_RS04810 (SALIVA_0984) - 991310..992077 (-) 768 WP_002884172.1 amino acid ABC transporter ATP-binding protein -
  SALIVA_RS04815 (SALIVA_0985) - 992268..992918 (-) 651 WP_014634409.1 amino acid ABC transporter permease -
  SALIVA_RS04820 (SALIVA_0986) - 992930..993628 (-) 699 WP_014633207.1 amino acid ABC transporter permease -
  SALIVA_RS04825 (SALIVA_0987) - 993646..994479 (-) 834 WP_014634410.1 transporter substrate-binding domain-containing protein -
  SALIVA_RS04830 (SALIVA_0988) - 994489..995256 (-) 768 WP_014634411.1 amino acid ABC transporter ATP-binding protein -
  SALIVA_RS04835 (SALIVA_0989) vicR 995541..996248 (+) 708 WP_014634412.1 response regulator YycF Regulator
  SALIVA_RS04840 (SALIVA_0990) vicK 996241..997581 (+) 1341 WP_014634413.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SALIVA_RS04845 (SALIVA_0991) vicX 997587..998399 (+) 813 WP_013990680.1 MBL fold metallo-hydrolase Regulator
  SALIVA_RS04850 (SALIVA_0992) - 998458..998817 (+) 360 WP_014634414.1 YbaN family protein -
  SALIVA_RS04855 (SALIVA_0993) - 998869..1000083 (-) 1215 WP_014634415.1 aminoacyltransferase -
  SALIVA_RS04860 (SALIVA_0994) yidA 1000085..1000894 (-) 810 WP_002885000.1 sugar-phosphatase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27045.85 Da        Isoelectric Point: 4.7589

>NTDB_id=49466 SALIVA_RS04835 WP_014634412.1 995541..996248(+) (vicR) [Streptococcus salivarius JIM8777]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAENPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVDESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=49466 SALIVA_RS04835 WP_014634412.1 995541..996248(+) (vicR) [Streptococcus salivarius JIM8777]
ATGAAAAAAATTCTAGTTGTTGATGACGAAAGACCAATTTCGGACATCATCAAGTTTAACCTGACAAAAGAAGGTTATGA
AGTGGTTACGGCTTTTGATGGTCGTGAAGCTTTGGAGCAGTTTGAAGCTGAGAATCCTGACTTGGTAATCTTGGACTTAA
TGTTGCCTGAATTGGATGGCCTGGAAGTTGCTAAGGAAATTCGAAAAACAAGTCATACACCCATTATCATGCTTTCAGCT
AAGGATAGTGAGTTTGATAAGGTTATTGGTCTTGAAATTGGGGCGGATGACTATGTGACTAAACCATTTTCTAACCGTGA
ATTGTTGGCTCGTATTAAGGCTCATTTGCGTCGTACAGAAACGATTGAAACTGCAGTAGATGAAAGCTCTAACTCTGGTA
AGCAAGAAATTTCAATTGGTGAGTTGATTATTGTTCCGGATGCCTTTGTTGCCAAAAAACGTGGAAATGAAGTTGAGTTG
ACCCACCGTGAATTTGAATTACTCTTTCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGCACTGTGGATGTAACGATTCGTCGTCTGCGTGAAAAGATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

86.383

100

0.864
  micA Streptococcus pneumoniae Cp1015

80.687

99.149

0.8
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

38.559

100

0.387

Multiple sequence alignment