Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   SALIVA_RS04840 Genome accession   NC_017595
Coordinates   996241..997581 (+) Length   446 a.a.
NCBI ID   WP_014634413.1    Uniprot ID   -
Organism   Streptococcus salivarius JIM8777     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 991241..1002581
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SALIVA_RS04810 (SALIVA_0984) - 991310..992077 (-) 768 WP_002884172.1 amino acid ABC transporter ATP-binding protein -
  SALIVA_RS04815 (SALIVA_0985) - 992268..992918 (-) 651 WP_014634409.1 amino acid ABC transporter permease -
  SALIVA_RS04820 (SALIVA_0986) - 992930..993628 (-) 699 WP_014633207.1 amino acid ABC transporter permease -
  SALIVA_RS04825 (SALIVA_0987) - 993646..994479 (-) 834 WP_014634410.1 transporter substrate-binding domain-containing protein -
  SALIVA_RS04830 (SALIVA_0988) - 994489..995256 (-) 768 WP_014634411.1 amino acid ABC transporter ATP-binding protein -
  SALIVA_RS04835 (SALIVA_0989) vicR 995541..996248 (+) 708 WP_014634412.1 response regulator YycF Regulator
  SALIVA_RS04840 (SALIVA_0990) vicK 996241..997581 (+) 1341 WP_014634413.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SALIVA_RS04845 (SALIVA_0991) vicX 997587..998399 (+) 813 WP_013990680.1 MBL fold metallo-hydrolase Regulator
  SALIVA_RS04850 (SALIVA_0992) - 998458..998817 (+) 360 WP_014634414.1 YbaN family protein -
  SALIVA_RS04855 (SALIVA_0993) - 998869..1000083 (-) 1215 WP_014634415.1 aminoacyltransferase -
  SALIVA_RS04860 (SALIVA_0994) yidA 1000085..1000894 (-) 810 WP_002885000.1 sugar-phosphatase -
  SALIVA_RS04865 (SALIVA_0995) - 1001072..1001938 (+) 867 WP_014634416.1 GNAT family N-acetyltransferase -
  SALIVA_RS04870 (SALIVA_0996) - 1002021..1002407 (+) 387 WP_002884910.1 DUF1934 domain-containing protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50901.24 Da        Isoelectric Point: 5.4134

>NTDB_id=49467 SALIVA_RS04840 WP_014634413.1 996241..997581(+) (vicK) [Streptococcus salivarius JIM8777]
MTSIGLSITSFELAILFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEKLRLKGDPELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDFETATQMSILDLLDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNTGKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=49467 SALIVA_RS04840 WP_014634413.1 996241..997581(+) (vicK) [Streptococcus salivarius JIM8777]
ATGACTAGTATTGGCTTAAGTATTACAAGCTTTGAACTAGCCATACTCTTTACGCTCCTCTTTGTTGCTTTCTATTTTAT
TTTTCTAGCTTATCGTGATTATCGACGAGTCAAAAATATCCGAAAGTTGACTAAGAGAGTTAAATCCCTTATGGCAGGAA
ATTATAATGAAAAATTACGCTTAAAGGGGGATCCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGACGTC
TTTCGTTTGACGCATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCAGTCCTCTCTTACATGAGTGATGGAGTTAT
TGCGACAAATCGTCGTGGTCAAATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTTTGAGACAGCGA
CACAGATGTCCATTTTAGATTTATTAGATGGTGAAAATCCCTATACTTATAGTGAATTGCTCTCTAAGACTCCTGAAATT
CATTTGTCACGTCGAGATGCCAACGATGAGTTTGTGACCTTACGTGTTAATTTTGCCCTTATTCGTAAAGAATCAGGTTT
TATCTCAGGTCTGGTTGCCGTTCTTCACGATGCCACTGAGCAAGAAAAAGAAGAGCGTGAACGTCGACTCTTCGTCTCAA
ACGTTAGTCATGAGTTGCGTACACCTTTGACTTCTGTAAAATCCTATCTGGAGGCACTTGATGATGGTGCTCTCGACGAA
GAGATTGCTCCTAACTTTATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGACCTCTTGGCACT
ATCACGTATTGACAATAAGAGTACCCAACTTGACGTTGAGATGACCAATTTCACGGCCTTCATGACCTATATCTTGAATC
GTTTTGATCAGATTAAAAGTCAAGAAACCAATACAGGTAAAACTTACGAAATCATTCGCGATTATCCGGTAAACTCAATT
TGGGTGGAGATTGATACAGATAAGATGACCCAGGTCGTGGATAATATTCTTAATAATGCTATCAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACAACTGATTCACAGTTGATCGTTTCTATTTCTGACCAAGGTTTGGGTATTCCTA
AGAAAGATTTGCCTCTGATTTTCGACCGTTTTTACCGTGTTGATAAGGCTAGAAGTCGTGCCCAAGGTGGAACTGGTCTA
GGCTTGTCCATTGCAAAAGAAATTATTAAACAACATAAGGGCTTTATTTGGGCTAAGAGTGAGTATGGTAAGGGTTCAAC
TTTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(94-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.913

92.825

0.686
  micB Streptococcus pneumoniae Cp1015

67.431

97.758

0.659

Multiple sequence alignment