Detailed information NTG0049405

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: SSAL_RS05495
• Genome accession: NC_017594
• Coordinates: 1210720..1211427 (-)
• Length: 235 a.a.
• NCBI ID: WP_014633204.1
• Uniprot ID: -
• Organism: Streptococcus salivarius 57.I
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1205720..1216427

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSAL_RS05470 (Ssal_01217)	tnpA	1206994..1207467 (-)	474	WP_002891962.1	IS200/IS605 family transposase	-
SSAL_RS05475	-	1207703..1207979 (-)	277	Protein_1071	ISL3 family transposase	-
SSAL_RS05480 (Ssal_01218)	-	1208151..1208510 (-)	360	WP_014633202.1	YbaN family protein	-
SSAL_RS05485 (Ssal_01219)	vicX	1208569..1209381 (-)	813	WP_013990680.1	MBL fold metallo-hydrolase	Regulator
SSAL_RS05490 (Ssal_01220)	vicK	1209387..1210727 (-)	1341	WP_014633203.1	cell wall metabolism sensor histidine kinase VicK	Regulator
SSAL_RS05495 (Ssal_01221)	vicR	1210720..1211427 (-)	708	WP_014633204.1	response regulator YycF	Regulator
SSAL_RS05500 (Ssal_01222)	-	1211713..1212480 (+)	768	WP_014633205.1	amino acid ABC transporter ATP-binding protein	-
SSAL_RS05505 (Ssal_01223)	-	1212490..1213323 (+)	834	WP_014633206.1	transporter substrate-binding domain-containing protein	-
SSAL_RS05510 (Ssal_01224)	-	1213341..1214039 (+)	699	WP_014633207.1	amino acid ABC transporter permease	-
SSAL_RS05515 (Ssal_01225)	-	1214051..1214701 (+)	651	WP_002886253.1	amino acid ABC transporter permease	-
SSAL_RS05520 (Ssal_01226)	endA	1214779..1215660 (-)	882	WP_045001786.1	DNA/RNA non-specific endonuclease	Machinery gene
SSAL_RS05525 (Ssal_01228)	-	1215722..1215910 (-)	189	WP_014633209.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27089.95 Da
• Isoelectric Point: 4.8387

>NTDB_id=49405 SSAL_RS05495 WP_014633204.1 1210720..1211427(-) (vicR) [Streptococcus salivarius 57.I]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEVEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETASEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=49405 SSAL_RS05495 WP_014633204.1 1210720..1211427(-) (vicR) [Streptococcus salivarius 57.I]
ATGAAAAAAATTCTAGTAGTTGATGATGAAAGACCAATCTCGGATATCATCAAGTTTAATCTGACTAAAGAGGGTTATGA
AGTTGTTACGGCGTTTGATGGTCGTGAAGCTTTAGAGCAGTTTGAAGTTGAAAAACCAGACTTGGTCATCCTGGACTTGA
TGTTGCCTGAACTAGATGGCTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCACACACCAATTATCATGCTTTCCGCT
AAGGATAGCGAGTTCGATAAGGTTATCGGGCTAGAAATTGGGGCGGACGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCATCAGAAGAAAGCTCTAACTCTGGTA
AGCAGGAGATTTCAATTGGTGAGTTGATAATTGTTCCAGATGCGTTTGTTGCTAAAAAACGTGGAAATGAAGTCGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATCTGGCAACTCACATGGGACAAGTGATGACGCGTGAGCATTTACTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

• Response regulator receiver domain (Response_reg) (4-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Streptococcus salivarius strain HSISS4	44.872	99.574	0.447
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.022	98.298	0.443
scnR	Streptococcus mutans UA159	38.075	100	0.387