Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   INP89_RS08100 Genome accession   NZ_CP063127
Coordinates   1635448..1636785 (+) Length   445 a.a.
NCBI ID   WP_197541622.1    Uniprot ID   -
Organism   Haemophilus influenzae strain M1C112_1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1630448..1641785
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP89_RS08075 (INP89_08070) - 1630510..1633104 (-) 2595 WP_197541620.1 penicillin-binding protein 1A -
  INP89_RS08080 (INP89_08075) comA 1633203..1634000 (+) 798 WP_116967004.1 pilus assembly protein PilM Machinery gene
  INP89_RS08085 (INP89_08080) comB 1634001..1634510 (+) 510 WP_197541621.1 competence protein B Machinery gene
  INP89_RS08090 (INP89_08085) comC 1634507..1635028 (+) 522 WP_048949854.1 competence protein ComC Machinery gene
  INP89_RS08095 (INP89_08090) comD 1635025..1635438 (+) 414 WP_048949853.1 pilus assembly protein PilP Machinery gene
  INP89_RS08100 (INP89_08095) comE 1635448..1636785 (+) 1338 WP_197541622.1 type IV pilus secretin PilQ family protein Machinery gene
  INP89_RS08105 (INP89_08100) - 1636798..1637484 (+) 687 WP_116938794.1 ComF family protein -
  INP89_RS08110 (INP89_08105) nfuA 1637560..1638156 (+) 597 WP_005652130.1 Fe-S biogenesis protein NfuA -
  INP89_RS08115 (INP89_08110) nudC 1638223..1639017 (+) 795 WP_197541623.1 NAD(+) diphosphatase -
  INP89_RS08120 (INP89_08115) - 1639053..1639643 (+) 591 WP_197541624.1 YjaG family protein -
  INP89_RS08125 (INP89_08120) - 1639783..1640055 (+) 273 WP_005630954.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49133.38 Da        Isoelectric Point: 7.4429

>NTDB_id=493242 INP89_RS08100 WP_197541622.1 1635448..1636785(+) (comE) [Haemophilus influenzae strain M1C112_1]
MKKYFLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQQDVNLVMDETLESNISLRLDNIDMPRLLQ
IIAKSKKLTLNKDEGIYYLNGGQSGKGQVAGNLATNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSPTGSITFDERSN
LLVIQDDPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLTGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLAALKQKSAGKK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=493242 INP89_RS08100 WP_197541622.1 1635448..1636785(+) (comE) [Haemophilus influenzae strain M1C112_1]
ATGAAGAAATATTTTTTAAAGTGCGGTTATTTTTTAGTCTGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCCAAAAC
TGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCCCAAACATTGGAACAGTTGGCTTTTCAACAAGATG
TGAATTTAGTGATGGATGAAACATTAGAAAGTAATATTTCATTGAGATTAGATAATATTGATATGCCACGTTTACTACAA
ATAATCGCTAAAAGTAAGAAGCTTACTTTGAACAAAGATGAGGGCATTTACTATCTGAATGGCGGGCAATCAGGCAAAGG
GCAAGTTGCAGGAAATCTTGCTACAAATGAACCGCACTTAGTGAGTCATACGGTTAAACTCCATTTTGCTAAAGCCTCTG
AATTAATGAAATCCTTAACCACAGGGAGCGGTTCTTTGCTTTCTCCTACAGGGAGCATTACCTTTGATGAACGTAGTAAT
TTGCTGGTTATTCAGGATGATCCTCGTTCTGTGCAAAATATCAAAAAACTAATTGCTGAAATGGATAAACCTATTGAGCA
GATCGCTATTGAAGCACGTATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGTGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTTACAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTCGCGAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGTGCGTTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAGGGGACAGAAATTCCTTACATCGTGAGTAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCAGTA
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCCGTTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTAGTGATTTTCGTCACGCCGCATAT
TTTAAAAGCGGGGGAAACGTTAGCGGCGTTGAAACAAAAAAGTGCGGGCAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(269-429)

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

96.18

100

0.962
  comE Haemophilus influenzae 86-028NP

95.955

100

0.96
  comE Glaesserella parasuis strain SC1401

52.471

95.506

0.501
  pilQ Vibrio campbellii strain DS40M4

43.128

94.831

0.409
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.718

92.584

0.396
  pilQ Vibrio cholerae strain A1552

42.718

92.584

0.396