Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Machinery gene
Locus tag   INP89_RS08095 Genome accession   NZ_CP063127
Coordinates   1635025..1635438 (+) Length   137 a.a.
NCBI ID   WP_048949853.1    Uniprot ID   -
Organism   Haemophilus influenzae strain M1C112_1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1630025..1640438
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP89_RS08075 (INP89_08070) - 1630510..1633104 (-) 2595 WP_197541620.1 penicillin-binding protein 1A -
  INP89_RS08080 (INP89_08075) comA 1633203..1634000 (+) 798 WP_116967004.1 pilus assembly protein PilM Machinery gene
  INP89_RS08085 (INP89_08080) comB 1634001..1634510 (+) 510 WP_197541621.1 competence protein B Machinery gene
  INP89_RS08090 (INP89_08085) comC 1634507..1635028 (+) 522 WP_048949854.1 competence protein ComC Machinery gene
  INP89_RS08095 (INP89_08090) comD 1635025..1635438 (+) 414 WP_048949853.1 pilus assembly protein PilP Machinery gene
  INP89_RS08100 (INP89_08095) comE 1635448..1636785 (+) 1338 WP_197541622.1 type IV pilus secretin PilQ family protein Machinery gene
  INP89_RS08105 (INP89_08100) - 1636798..1637484 (+) 687 WP_116938794.1 ComF family protein -
  INP89_RS08110 (INP89_08105) nfuA 1637560..1638156 (+) 597 WP_005652130.1 Fe-S biogenesis protein NfuA -
  INP89_RS08115 (INP89_08110) nudC 1638223..1639017 (+) 795 WP_197541623.1 NAD(+) diphosphatase -
  INP89_RS08120 (INP89_08115) - 1639053..1639643 (+) 591 WP_197541624.1 YjaG family protein -
  INP89_RS08125 (INP89_08120) - 1639783..1640055 (+) 273 WP_005630954.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 137 a.a.        Molecular weight: 15602.66 Da        Isoelectric Point: 4.3509

>NTDB_id=493241 INP89_RS08095 WP_048949853.1 1635025..1635438(+) (comD) [Haemophilus influenzae strain M1C112_1]
MKYWFFLTALLFINCSWGQDPFDKTQRNRSQFDNAQTVMEQTEIISSDVPNNLCGADENRQAAEIPLNALKLVGVVISKD
KAFALLQDQGLQVYSVLEGVDVAQEGYIVEKIDQNNVQFMRKLGEQCDSSEWKKLSF

Nucleotide


Download         Length: 414 bp        

>NTDB_id=493241 INP89_RS08095 WP_048949853.1 1635025..1635438(+) (comD) [Haemophilus influenzae strain M1C112_1]
ATGAAGTATTGGTTTTTCCTAACTGCATTGCTTTTTATAAATTGCAGTTGGGGGCAGGATCCTTTCGATAAAACACAACG
TAACCGTTCTCAGTTTGATAACGCACAAACAGTAATGGAACAGACAGAAATAATTTCCTCAGATGTACCTAATAATCTAT
GCGGAGCGGATGAAAATCGCCAAGCGGCTGAAATTCCTTTGAACGCTTTAAAATTGGTGGGCGTAGTGATTTCTAAAGAT
AAAGCCTTTGCCTTATTGCAAGATCAAGGTTTGCAAGTTTACAGCGTTTTAGAGGGTGTTGATGTGGCTCAAGAGGGCTA
TATTGTAGAAAAAATCGACCAAAACAATGTTCAATTTATGCGCAAGCTCGGAGAGCAATGTGATAGTAGTGAATGGAAAA
AATTAAGTTTTTAA

Domains

Predicted by InterproScan.

Pilus assembly protein, PilP (PilP)

(26-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Haemophilus influenzae Rd KW20

95.62

100

0.956
  comD Haemophilus influenzae 86-028NP

94.891

100

0.949