Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Machinery gene
Locus tag   INP89_RS08085 Genome accession   NZ_CP063127
Coordinates   1634001..1634510 (+) Length   169 a.a.
NCBI ID   WP_197541621.1    Uniprot ID   -
Organism   Haemophilus influenzae strain M1C112_1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1629001..1639510
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP89_RS08065 (INP89_08060) - 1629101..1629430 (-) 330 WP_105904681.1 YbaB/EbfC family nucleoid-associated protein -
  INP89_RS08070 (INP89_08065) - 1629589..1630434 (-) 846 WP_197541619.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  INP89_RS08075 (INP89_08070) - 1630510..1633104 (-) 2595 WP_197541620.1 penicillin-binding protein 1A -
  INP89_RS08080 (INP89_08075) comA 1633203..1634000 (+) 798 WP_116967004.1 pilus assembly protein PilM Machinery gene
  INP89_RS08085 (INP89_08080) comB 1634001..1634510 (+) 510 WP_197541621.1 competence protein B Machinery gene
  INP89_RS08090 (INP89_08085) comC 1634507..1635028 (+) 522 WP_048949854.1 competence protein ComC Machinery gene
  INP89_RS08095 (INP89_08090) comD 1635025..1635438 (+) 414 WP_048949853.1 pilus assembly protein PilP Machinery gene
  INP89_RS08100 (INP89_08095) comE 1635448..1636785 (+) 1338 WP_197541622.1 type IV pilus secretin PilQ family protein Machinery gene
  INP89_RS08105 (INP89_08100) - 1636798..1637484 (+) 687 WP_116938794.1 ComF family protein -
  INP89_RS08110 (INP89_08105) nfuA 1637560..1638156 (+) 597 WP_005652130.1 Fe-S biogenesis protein NfuA -
  INP89_RS08115 (INP89_08110) nudC 1638223..1639017 (+) 795 WP_197541623.1 NAD(+) diphosphatase -

Sequence

Protein


Download         Length: 169 a.a.        Molecular weight: 19919.83 Da        Isoelectric Point: 7.4000

>NTDB_id=493239 INP89_RS08085 WP_197541621.1 1634001..1634510(+) (comB) [Haemophilus influenzae strain M1C112_1]
MSMNLLPWRTYQHQNRLRRLAFYIALFILLAINLTLAFSNLIEQQKQDLQAQQTSFEQLNQQLYKTAKKIEQLRSAVQVG
EILTSIPNEQVKKSLQLLSELPFQQGELNKFKQDAHNLSLEGLAQDQREFELIHQFLKKHFPNVKLSQFQPEQQSLYFLF
DVEQVGEDK

Nucleotide


Download         Length: 510 bp        

>NTDB_id=493239 INP89_RS08085 WP_197541621.1 1634001..1634510(+) (comB) [Haemophilus influenzae strain M1C112_1]
ATGTCGATGAATTTATTGCCTTGGCGTACTTATCAACATCAAAACCGTTTACGTCGTTTAGCTTTTTATATCGCTTTATT
TATCTTGCTTGCTATTAATTTAACTTTGGCTTTTAGTAATTTAATTGAACAACAAAAACAAGATCTGCAAGCGCAGCAAA
CATCTTTTGAACAACTTAATCAGCAACTTTATAAAACCGCCAAGAAAATTGAACAGTTGCGTAGTGCAGTGCAGGTTGGC
GAAATTTTGACATCTATTCCCAACGAGCAAGTAAAAAAGAGTTTACAGCTGCTAAGTGAATTACCTTTTCAGCAAGGAGA
ACTGAATAAATTTAAACAAGATGCTCATAACTTAAGTTTGGAAGGTCTCGCACAAGATCAAAGAGAATTTGAACTGATTC
ATCAATTTTTAAAGAAACATTTTCCCAATGTGAAATTAAGCCAGTTTCAACCTGAACAACAGTCATTGTATTTTCTCTTT
GATGTGGAACAAGTTGGAGAAGATAAGTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Haemophilus influenzae 86-028NP

87.425

98.817

0.864
  comB Haemophilus influenzae Rd KW20

86.228

98.817

0.852