Detailed information NTG0049305

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: SPNINV200_RS02495
• Genome accession: NC_017593
• Coordinates: 476043..478196 (-)
• Length: 717 a.a.
• NCBI ID: WP_000205157.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae INV200
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 471043..483196

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPNINV200_RS02465 (SPNINV200_04640)	-	471374..471703 (-)	330	WP_000132572.1	hypothetical protein	-
SPNINV200_RS02470 (SPNINV200_04650)	-	471980..472318 (+)	339	WP_000682132.1	LytTR family DNA-binding domain-containing protein	-
SPNINV200_RS02475 (SPNINV200_04660)	comE/blpR	472323..473060 (+)	738	WP_001219146.1	response regulator transcription factor	Regulator
SPNINV200_RS02480 (SPNINV200_04670)	-	473074..474414 (+)	1341	WP_001099895.1	sensor histidine kinase	-
SPNINV200_RS02485 (SPNINV200_04680)	blpC	474459..474614 (-)	156	WP_000358814.1	quorum-sensing system pheromone BlpC	-
SPNINV200_RS02490 (SPNINV200_04690)	-	474671..476032 (-)	1362	WP_001069098.1	bacteriocin secretion accessory protein	-
SPNINV200_RS02495 (SPNINV200_04700)	comA/nlmT	476043..478196 (-)	2154	WP_000205157.1	peptide cleavage/export ABC transporter BlpA	Regulator
SPNINV200_RS02500 (SPNINV200_04710)	blpU	478477..478707 (+)	231	WP_001093268.1	bacteriocin-like peptide BlpU	-
SPNINV200_RS02505	-	478710..478829 (+)	120	WP_000346298.1	PncF family bacteriocin immunity protein	-
SPNINV200_RS11470 (SPNINV200_04720)	-	479126..479290 (+)	165	WP_000727118.1	hypothetical protein	-
SPNINV200_RS02520	-	479287..479691 (+)	405	WP_000846944.1	hypothetical protein	-
SPNINV200_RS11475	-	479889..480694 (+)	806	Protein_477	IS5 family transposase	-
SPNINV200_RS02535 (SPNINV200_04750)	blpM	480896..481150 (+)	255	WP_000379879.1	two-peptide bacteriocin subunit BlpM	-
SPNINV200_RS02540 (SPNINV200_04760)	blpN	481166..481369 (+)	204	WP_001099492.1	two-peptide bacteriocin subunit BlpN	-
SPNINV200_RS02545	cipB	481613..481762 (+)	150	WP_001813641.1	bacteriocin-like peptide BlpO	Regulator
SPNINV200_RS02550 (SPNINV200_04790)	-	481866..481985 (+)	120	WP_000346296.1	PncF family bacteriocin immunity protein	-
SPNINV200_RS02560 (SPNINV200_04810)	-	482771..483154 (+)	384	WP_000877378.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80722.74 Da
• Isoelectric Point: 7.6796

>NTDB_id=49305 SPNINV200_RS02495 WP_000205157.1 476043..478196(-) (comA/nlmT) [Streptococcus pneumoniae INV200]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMF
IIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKL
VLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQAPENPVHSHFL
MGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHI
NYLPQQAYIFNGSILENLTLGGNHMISQEDILKACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 2154 bp

>NTDB_id=49305 SPNINV200_RS02495 WP_000205157.1 476043..478196(-) (comA/nlmT) [Streptococcus pneumoniae INV200]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGGCCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTCCCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCTTCCTTCCTCTG
ATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATCGGTGGTTCTTA
CTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTA
TCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATTGAT
GTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTC
ACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGA
TTCTTGTAGGGGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATGTTC
ATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCAT
TATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAAT
TTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTA
GTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTT
TAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTTG
CTAATAACCGTTTGAACGAAGTCTATCTAGTCGAGTCTGAGTTCCAAGCCCCAGAAAACCCTGTTCATTCACATTTTTTG
ATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGAT
TAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCT
TTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATT
AATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGATTAG
CCAAGAAGATATTCTAAAAGCTTGTGAATTAGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTC
AGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAAGCTCCT
GTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATATCCCTAAC
TGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGGGGA
AAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (169-438)

• ABC transporter (ABC_tran) (500-649)

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.028	99.721	0.718
comA	Streptococcus mitis NCTC 12261	66.48	99.442	0.661
comA	Streptococcus pneumoniae Rx1	66.199	99.442	0.658
comA	Streptococcus pneumoniae D39	66.199	99.442	0.658
comA	Streptococcus pneumoniae R6	66.199	99.442	0.658
comA	Streptococcus mitis SK321	65.919	99.442	0.656
comA	Streptococcus pneumoniae TIGR4	65.919	99.442	0.656
comA	Streptococcus gordonii str. Challis substr. CH1	65.181	100	0.653