Detailed information NTG0048690

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: STND_RS01480
• Genome accession: NC_017563
• Coordinates: 265049..265948 (+)
• Length: 299 a.a.
• NCBI ID: WP_014607953.1
• Uniprot ID: A0AAN1ZWJ0
• Organism: Streptococcus thermophilus ND03
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 260049..270948

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STND_RS01460 (STND_0263)	trkA	261185..262534 (-)	1350	WP_014607951.1	Trk system potassium transporter TrkA	-
STND_RS01465 (STND_0264)	-	262823..263332 (+)	510	WP_014607952.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
STND_RS01470 (STND_0265)	-	263644..264201 (+)	558	WP_002949523.1	ECF transporter S component	-
STND_RS01475 (STND_0266)	-	264204..264854 (+)	651	WP_011225447.1	phosphatase PAP2 family protein	-
STND_RS01480 (STND_0267)	comR	265049..265948 (+)	900	WP_014607953.1	helix-turn-helix domain-containing protein	Regulator
STND_RS11450	-	266186..266617 (+)	432	Protein_244	cysteine peptidase family C39 domain-containing protein	-
STND_RS11455	-	266647..267312 (+)	666	Protein_245	ABC transporter transmembrane domain-containing protein	-
STND_RS11460	comA	267385..267594 (+)	210	WP_002946147.1	hypothetical protein	Regulator
STND_RS01505	-	267649..268217 (+)	569	Protein_247	ATP-binding cassette domain-containing protein	-
STND_RS01510 (STND_0271)	-	268325..268642 (+)	318	WP_011225454.1	DUF805 domain-containing protein	-
STND_RS11465	-	268605..268889 (-)	285	WP_014727318.1	hypothetical protein	-
STND_RS11470	-	269129..270025 (-)	897	WP_224102957.1	urease cluster protein	-
STND_RS01520 (STND_0273)	-	270430..270945 (+)	516	WP_002949547.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35289.70 Da
• Isoelectric Point: 5.0061

>NTDB_id=48690 STND_RS01480 WP_014607953.1 265049..265948(+) (comR) [Streptococcus thermophilus ND03]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIENS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=48690 STND_RS01480 WP_014607953.1 265049..265948(+) (comR) [Streptococcus thermophilus ND03]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAACTCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418