Detailed information NTG0481429

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: D39N_RS09295
• Genome accession: NZ_CP061208
• Coordinates: 1840127..1840588 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250534.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain D39_P0
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1835127..1845588

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D39N_RS09265 (D39N_01859)	-	1835431..1836255 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
D39N_RS09270 (D39N_01860)	rnpA	1836230..1836601 (-)	372	WP_000739246.1	ribonuclease P protein component	-
D39N_RS10860	-	1836618..1836749 (-)	132	WP_000768904.1	hypothetical protein	-
D39N_RS09275 (D39N_01861)	-	1836750..1837940 (-)	1191	WP_000167757.1	acetate kinase	-
D39N_RS09280 (D39N_01862)	comYH	1837991..1838944 (-)	954	WP_000345135.1	class I SAM-dependent methyltransferase	Machinery gene
D39N_RS09285	-	1839005..1839599 (-)	595	Protein_1833	methyltransferase domain-containing protein	-
D39N_RS09290 (D39N_01865)	comGG/cglG	1839736..1840149 (-)	414	WP_000265622.1	competence type IV pilus minor pilin ComGG	Machinery gene
D39N_RS09295 (D39N_01866)	comGF/cglF	1840127..1840588 (-)	462	WP_000250534.1	competence type IV pilus minor pilin ComGF	Machinery gene
D39N_RS09300 (D39N_01867)	comGE/cglE	1840551..1840853 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
D39N_RS09305 (D39N_01868)	comGD/cglD	1840816..1841220 (-)	405	WP_000588026.1	competence type IV pilus minor pilin ComGD	Machinery gene
D39N_RS09310 (D39N_01869)	comGC/cglC	1841213..1841539 (-)	327	WP_000738626.1	comG operon protein ComGC	Machinery gene
D39N_RS09315 (D39N_01870)	comGB/cglB	1841541..1842557 (-)	1017	WP_074196785.1	competence type IV pilus assembly protein ComGB	Machinery gene
D39N_RS09320 (D39N_01871)	comGA/cglA/cilD	1842505..1843446 (-)	942	WP_000249564.1	competence type IV pilus ATPase ComGA	Machinery gene
D39N_RS09325 (D39N_01872)	-	1843522..1843887 (-)	366	WP_000286412.1	DUF1033 family protein	-
D39N_RS09330 (D39N_01873)	-	1844038..1845096 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17972.67 Da
• Isoelectric Point: 9.6092

>NTDB_id=481429 D39N_RS09295 WP_000250534.1 1840127..1840588(-) (comGF/cglF) [Streptococcus pneumoniae strain D39_P0]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSVRITEDNQLVRFHFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=481429 D39N_RS09295 WP_000250534.1 1840127..1840588(-) (comGF/cglF) [Streptococcus pneumoniae strain D39_P0]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGATGATTTCCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGACTCAAATCTGTACGGATTACAGAGGACAATCAACTGGTTCGCTTTCATT
TCCAGTTCCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	100	100	1
comGF/cglF	Streptococcus pneumoniae D39	100	100	1
comGF/cglF	Streptococcus pneumoniae R6	100	100	1
comGF/cglF	Streptococcus pneumoniae TIGR4	100	100	1
comGF/cglF	Streptococcus mitis SK321	90.85	100	0.909
comGF/cglF	Streptococcus mitis NCTC 12261	89.542	100	0.895