Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   D39N_RS09300 Genome accession   NZ_CP061208
Coordinates   1840551..1840853 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain D39_P0     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1835551..1845853
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D39N_RS09270 (D39N_01860) rnpA 1836230..1836601 (-) 372 WP_000739246.1 ribonuclease P protein component -
  D39N_RS10860 - 1836618..1836749 (-) 132 WP_000768904.1 hypothetical protein -
  D39N_RS09275 (D39N_01861) - 1836750..1837940 (-) 1191 WP_000167757.1 acetate kinase -
  D39N_RS09280 (D39N_01862) comYH 1837991..1838944 (-) 954 WP_000345135.1 class I SAM-dependent methyltransferase Machinery gene
  D39N_RS09285 - 1839005..1839599 (-) 595 Protein_1833 methyltransferase domain-containing protein -
  D39N_RS09290 (D39N_01865) comGG/cglG 1839736..1840149 (-) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  D39N_RS09295 (D39N_01866) comGF/cglF 1840127..1840588 (-) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  D39N_RS09300 (D39N_01867) comGE/cglE 1840551..1840853 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  D39N_RS09305 (D39N_01868) comGD/cglD 1840816..1841220 (-) 405 WP_000588026.1 competence type IV pilus minor pilin ComGD Machinery gene
  D39N_RS09310 (D39N_01869) comGC/cglC 1841213..1841539 (-) 327 WP_000738626.1 comG operon protein ComGC Machinery gene
  D39N_RS09315 (D39N_01870) comGB/cglB 1841541..1842557 (-) 1017 WP_074196785.1 competence type IV pilus assembly protein ComGB Machinery gene
  D39N_RS09320 (D39N_01871) comGA/cglA/cilD 1842505..1843446 (-) 942 WP_000249564.1 competence type IV pilus ATPase ComGA Machinery gene
  D39N_RS09325 (D39N_01872) - 1843522..1843887 (-) 366 WP_000286412.1 DUF1033 family protein -
  D39N_RS09330 (D39N_01873) - 1844038..1845096 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=481430 D39N_RS09300 WP_000413382.1 1840551..1840853(-) (comGE/cglE) [Streptococcus pneumoniae strain D39_P0]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=481430 D39N_RS09300 WP_000413382.1 1840551..1840853(-) (comGE/cglE) [Streptococcus pneumoniae strain D39_P0]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4