Detailed information NTG0479803

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: IBC03_RS01510
• Genome accession: NZ_CP061025
• Coordinates: 273300..274199 (+)
• Length: 299 a.a.
• NCBI ID: WP_014607953.1
• Uniprot ID: A0AAN1ZWJ0
• Organism: Streptococcus thermophilus strain 13496
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 268300..279199

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IBC03_RS01490 (IBC03_01495)	trkA	269436..270785 (-)	1350	WP_014607951.1	Trk system potassium transporter TrkA	-
IBC03_RS01495 (IBC03_01500)	-	271074..271583 (+)	510	WP_014607952.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
IBC03_RS01500 (IBC03_01505)	-	271895..272452 (+)	558	WP_002949523.1	ECF transporter S component	-
IBC03_RS01505 (IBC03_01510)	-	272455..273105 (+)	651	WP_011225447.1	phosphatase PAP2 family protein	-
IBC03_RS01510 (IBC03_01515)	comR	273300..274199 (+)	900	WP_014607953.1	helix-turn-helix domain-containing protein	Regulator
IBC03_RS09925	-	274437..274868 (+)	432	Protein_244	cysteine peptidase family C39 domain-containing protein	-
IBC03_RS09930	-	274898..275614 (+)	717	Protein_245	ABC transporter transmembrane domain-containing protein	-
IBC03_RS09935	comA	275636..275845 (+)	210	WP_002946147.1	hypothetical protein	Regulator
IBC03_RS01535 (IBC03_01540)	-	275900..276468 (+)	569	Protein_247	ATP-binding cassette domain-containing protein	-
IBC03_RS01540 (IBC03_01545)	-	276583..277518 (+)	936	WP_138496752.1	IS30 family transposase	-
IBC03_RS01545 (IBC03_01550)	-	277637..277954 (+)	318	WP_011225454.1	DUF805 domain-containing protein	-
IBC03_RS09940	-	277917..278201 (-)	285	WP_014727318.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35289.70 Da
• Isoelectric Point: 5.0061

>NTDB_id=479803 IBC03_RS01510 WP_014607953.1 273300..274199(+) (comR) [Streptococcus thermophilus strain 13496]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIENS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=479803 IBC03_RS01510 WP_014607953.1 273300..274199(+) (comR) [Streptococcus thermophilus strain 13496]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAACTCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418