Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   NMBM01240149_RS11100 Genome accession   NC_017514
Coordinates   2142929..2144116 (-) Length   395 a.a.
NCBI ID   WP_002218551.1    Uniprot ID   -
Organism   Neisseria meningitidis M01-240149     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 2137929..2149116
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMBM01240149_RS11080 (NMBM01240149_1969) - 2138354..2139301 (+) 948 WP_002218555.1 hypothetical protein -
  NMBM01240149_RS11085 (NMBM01240149_1970) - 2139301..2139720 (+) 420 WP_002218553.1 hypothetical protein -
  NMBM01240149_RS13535 - 2139717..2139986 (+) 270 WP_206696354.1 YkgJ family cysteine cluster protein -
  NMBM01240149_RS11090 (NMBM01240149_1971) topA 2140064..2142370 (-) 2307 WP_002218552.1 type I DNA topoisomerase -
  NMBM01240149_RS11095 (NMBM01240149_1972) - 2142442..2142903 (-) 462 WP_002215351.1 DUF494 domain-containing protein -
  NMBM01240149_RS11100 (NMBM01240149_1973) dprA 2142929..2144116 (-) 1188 WP_002218551.1 DNA-processing protein DprA Machinery gene
  NMBM01240149_RS11105 (NMBM01240149_1974) - 2144207..2145484 (-) 1278 WP_002218550.1 sigma-54-dependent transcriptional regulator -
  NMBM01240149_RS11110 (NMBM01240149_1975) - 2145477..2147597 (-) 2121 WP_002223289.1 sensor histidine kinase -
  NMBM01240149_RS11115 (NMBM01240149_1976) - 2147597..2148196 (-) 600 WP_002216221.1 DUF4390 domain-containing protein -

Sequence

Protein


Download         Length: 395 a.a.        Molecular weight: 41801.77 Da        Isoelectric Point: 5.9333

>NTDB_id=47979 NMBM01240149_RS11100 WP_002218551.1 2142929..2144116(-) (dprA) [Neisseria meningitidis M01-240149]
MTEDERFAWLQLAFTPYIGAESFLLLLRRFGSASNALSAPAEQVAPAVRHKQAAEAWRNAEKRASARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGKSLGGQNIPVVSGMASGIDT
AAHQGALEAEGGTIAVWGTGIDRIYPPSNKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLVECLDDILNECPGLLQNTGASSYSINKDTPDTGSRAVQT
AYAPPPAAKMPSEGAAGGTAVGGILDKMGFDPIHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide


Download         Length: 1188 bp        

>NTDB_id=47979 NMBM01240149_RS11100 WP_002218551.1 2142929..2144116(-) (dprA) [Neisseria meningitidis M01-240149]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGCTTCCTGCTGCTGCT
GCGCCGTTTCGGCAGCGCGTCAAACGCCCTGTCCGCACCGGCGGAACAGGTCGCCCCGGCGGTGCGGCACAAGCAGGCGG
CCGAGGCTTGGCGCAATGCGGAAAAACGCGCCTCGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGTCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAAGTCGTTGGGCGGGCAAAATATCCCCGTTGTGTCGGGTATGGCTTCCGGTATCGATACT
GCCGCCCATCAGGGCGCACTGGAGGCAGAAGGCGGCACCATCGCCGTGTGGGGGACGGGTATAGACCGCATTTACCCGCC
GTCCAATAAAAACCTTGCCTATGAAATCGCCGAAAAAGGATTGATTGTCAGCGAGTTTCCCATCGGTACGCGCCCGTATG
CCGGCAACTTTCCGCGCCGCAACCGCCTGATTGCCGCGCTGTCGCAGGTTACGCTGGTGGTTGAAGCTGCGTTGGAATCC
GGTTCGCTGATTACCGCCGGCTTGGCGGCAGAAATGGGGCGCGAAGTGATGGCGGTACCCGGTTCGATAGACAATCCGCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGCGCGAAATTGGTGGAATGCCTGGACGACATCCTGAACGAATGCCCGG
GGCTATTGCAAAATACGGGTGCTTCATCATATTCTATAAATAAGGATACGCCCGACACGGGCAGTCGCGCCGTTCAGACG
GCATACGCCCCGCCGCCTGCCGCAAAAATGCCGTCTGAAGGGGCGGCAGGCGGCACAGCCGTCGGCGGCATACTGGATAA
AATGGGTTTCGACCCCATCCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCGCACTGT
TGGAATTGGAATTGGACGGCAGCGTTGCCGCAATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(341-388)

DNA recombination-mediator protein A (DNA_processg_A)

(79-283)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Neisseria gonorrhoeae MS11

96.203

100

0.962
  dprA Neisseria gonorrhoeae strain FA1090

95.949

100

0.959
  dprA Neisseria meningitidis MC58

90.176

100

0.906
  dprA Neisseria meningitidis strain C311

90.176

100

0.906
  dprA Glaesserella parasuis strain SC1401

40.576

96.709

0.392
  dprA Vibrio cholerae strain A1552

37.531

100

0.377
  dprA Vibrio campbellii strain DS40M4

36.856

98.228

0.362

Multiple sequence alignment