Detailed information NTG0479572

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: IBB97_RS01505
• Genome accession: NZ_CP061021
• Coordinates: 272237..273136 (+)
• Length: 299 a.a.
• NCBI ID: WP_014607953.1
• Uniprot ID: A0AAN1ZWJ0
• Organism: Streptococcus thermophilus strain 24739
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 267237..278136

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IBB97_RS01485 (IBB97_01490)	trkA	268373..269722 (-)	1350	WP_014607951.1	Trk system potassium transporter TrkA	-
IBB97_RS01490 (IBB97_01495)	-	270011..270520 (+)	510	WP_014607952.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
IBB97_RS01495 (IBB97_01500)	-	270832..271389 (+)	558	WP_002949523.1	ECF transporter S component	-
IBB97_RS01500 (IBB97_01505)	-	271392..272042 (+)	651	WP_011225447.1	phosphatase PAP2 family protein	-
IBB97_RS01505 (IBB97_01510)	comR	272237..273136 (+)	900	WP_014607953.1	helix-turn-helix domain-containing protein	Regulator
IBB97_RS10165	-	273374..273805 (+)	432	Protein_243	cysteine peptidase family C39 domain-containing protein	-
IBB97_RS10170	-	273835..274551 (+)	717	Protein_244	ABC transporter transmembrane domain-containing protein	-
IBB97_RS10175	comA	274573..274782 (+)	210	WP_002946147.1	hypothetical protein	Regulator
IBB97_RS01530 (IBB97_01535)	-	274837..275405 (+)	569	Protein_246	ATP-binding cassette domain-containing protein	-
IBB97_RS01535 (IBB97_01540)	-	275520..276455 (+)	936	WP_138496752.1	IS30 family transposase	-
IBB97_RS01540 (IBB97_01545)	-	276574..276891 (+)	318	WP_011225454.1	DUF805 domain-containing protein	-
IBB97_RS10180	-	276854..277138 (-)	285	WP_014727318.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35289.70 Da
• Isoelectric Point: 5.0061

>NTDB_id=479572 IBB97_RS01505 WP_014607953.1 272237..273136(+) (comR) [Streptococcus thermophilus strain 24739]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIENS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=479572 IBB97_RS01505 WP_014607953.1 272237..273136(+) (comR) [Streptococcus thermophilus strain 24739]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAACTCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418