Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   J1N58_RS01280 Genome accession   NZ_CP071697
Coordinates   253171..254532 (-) Length   453 a.a.
NCBI ID   WP_024378067.1    Uniprot ID   -
Organism   Streptococcus suis strain 1112S     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 248171..259532
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J1N58_RS11720 - 248876..249274 (-) 399 WP_029180393.1 hypothetical protein -
  J1N58_RS01250 (J1N58_01250) - 249500..249727 (+) 228 WP_024376261.1 hypothetical protein -
  J1N58_RS01255 (J1N58_01255) - 249708..250013 (+) 306 WP_044672279.1 hypothetical protein -
  J1N58_RS01260 (J1N58_01260) - 250304..250645 (+) 342 WP_024378069.1 LytTR family DNA-binding domain-containing protein -
  J1N58_RS01265 (J1N58_01265) comE/blpR 250645..251385 (+) 741 WP_024376264.1 response regulator transcription factor Regulator
  J1N58_RS01270 (J1N58_01270) - 251395..252726 (+) 1332 WP_099780237.1 GHKL domain-containing protein -
  J1N58_RS01275 (J1N58_01275) - 252924..253073 (-) 150 WP_079267743.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  J1N58_RS01280 (J1N58_01280) comB 253171..254532 (-) 1362 WP_024378067.1 bacteriocin secretion accessory protein Regulator
  J1N58_RS01285 (J1N58_01285) comA/nlmT 254542..256695 (-) 2154 WP_024376267.1 peptide cleavage/export ABC transporter Regulator
  J1N58_RS01290 (J1N58_01290) - 257000..257230 (+) 231 WP_024376268.1 bacteriocin class II family protein -
  J1N58_RS01295 (J1N58_01295) - 257232..257423 (+) 192 WP_024376269.1 hypothetical protein -
  J1N58_RS01300 (J1N58_01300) - 257926..258066 (+) 141 WP_153308671.1 hypothetical protein -
  J1N58_RS01305 (J1N58_01305) - 258086..258226 (+) 141 WP_153308672.1 hypothetical protein -
  J1N58_RS01310 (J1N58_01310) - 258241..258852 (+) 612 WP_024378066.1 type II CAAX endopeptidase family protein -
  J1N58_RS01315 (J1N58_01315) - 259014..259310 (+) 297 WP_024376271.1 bacteriocin immunity protein -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 49609.88 Da        Isoelectric Point: 4.9973

>NTDB_id=478351 J1N58_RS01280 WP_024378067.1 253171..254532(-) (comB) [Streptococcus suis strain 1112S]
MNTNLFRSAEFYQRRYHNFATLLILPLVLLVSFLFLFSFLAKKEVTVTSRGEITPTKVIASIQSTSNNPILANHLVANQA
VKKGDALIQYAETMEASQKQALESQVHNLEEQKKGLETLRNSLEQGTNLFTGEDNFGYGATFQQFVSQTQDLELGIAKTN
AEVTNQAALANHTAAAIDQQLSQLQQDIIAYEELKTAISTQASSLPTGNPHQATLNNYLAQLQGTPNPALSDQYISQINQ
TIAGLENSMASLSIQRAGTGSIATYDTSLATKIESLRAQFLQNAAQQLTTVESQLLQAKSQLDQAATQLEQTTITAPENG
VIALNPEFEGKNLIPVGSDIAYLYPDIKQTKTVLITYYVTSEYVALLKEGQTARLSLEKIGNQPIIVIGSIQSIAQSATP
TEEGNLFKITAQATITENESSLLQYGLQGRVTSVIAKKTFFDYYKDKLLHTNN

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=478351 J1N58_RS01280 WP_024378067.1 253171..254532(-) (comB) [Streptococcus suis strain 1112S]
ATGAATACAAACCTATTTCGAAGTGCTGAATTTTATCAGCGACGCTACCATAATTTTGCGACCCTTTTGATTCTCCCCTT
GGTACTACTGGTCTCCTTCCTTTTTCTCTTCTCCTTCCTAGCTAAAAAAGAAGTCACTGTCACTTCACGAGGAGAGATTA
CTCCTACCAAGGTCATCGCCTCCATTCAATCAACCAGTAACAATCCTATTCTTGCCAATCATCTCGTAGCCAATCAAGCC
GTAAAAAAAGGCGATGCTCTCATCCAGTACGCCGAAACAATGGAGGCTTCCCAGAAGCAAGCCTTAGAAAGTCAAGTTCA
TAACCTAGAAGAGCAGAAAAAAGGGTTGGAGACCTTACGAAACAGTCTTGAACAGGGTACCAACCTCTTTACAGGAGAAG
ATAACTTTGGCTACGGAGCAACCTTTCAGCAATTCGTCAGCCAAACACAAGACCTAGAATTAGGTATCGCTAAAACGAAT
GCCGAGGTCACTAATCAAGCAGCTTTGGCCAATCACACCGCTGCTGCTATTGACCAACAACTCAGTCAACTCCAGCAGGA
CATCATCGCCTACGAGGAGCTTAAAACAGCGATTAGCACCCAAGCAAGTAGCTTGCCGACAGGCAATCCCCACCAGGCCA
CTCTGAACAACTACCTAGCCCAACTCCAAGGAACACCAAATCCTGCCCTTAGTGATCAATACATCAGCCAGATTAACCAA
ACCATCGCAGGATTGGAAAACTCAATGGCTAGCCTCTCTATTCAACGGGCAGGTACTGGTAGCATCGCCACCTACGACAC
AAGTCTAGCGACTAAAATCGAAAGTTTACGTGCCCAGTTTCTACAAAACGCAGCTCAGCAACTGACCACTGTCGAATCTC
AATTGCTTCAGGCAAAGTCGCAACTCGATCAAGCAGCTACTCAATTAGAACAAACTACCATTACCGCTCCAGAAAATGGT
GTCATCGCCCTAAATCCTGAGTTCGAGGGAAAAAACTTGATTCCAGTAGGGAGCGATATCGCCTATCTCTATCCTGATAT
CAAGCAAACCAAGACCGTCCTTATCACCTACTATGTGACTTCGGAGTATGTCGCCCTCCTCAAAGAAGGCCAGACCGCCC
GACTAAGCTTAGAGAAAATCGGCAATCAGCCAATCATAGTCATCGGCTCCATCCAGTCTATCGCTCAATCCGCAACACCG
ACAGAAGAGGGCAATCTCTTTAAGATTACAGCCCAAGCTACCATTACAGAAAATGAAAGCTCACTTCTACAGTATGGTCT
ACAGGGTCGCGTCACCAGTGTGATTGCTAAGAAGACCTTCTTCGACTACTACAAAGATAAACTGCTTCACACAAATAATT
AA

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(313-426)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

38

99.338

0.377
  comB Streptococcus mitis NCTC 12261

37.778

99.338

0.375
  comB Streptococcus pneumoniae D39

37.556

99.338

0.373
  comB Streptococcus pneumoniae R6

37.556

99.338

0.373
  comB Streptococcus pneumoniae Rx1

37.556

99.338

0.373
  comB Streptococcus gordonii str. Challis substr. CH1

37.251

99.558

0.371
  comB Streptococcus mitis SK321

37.111

99.338

0.369