Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   J3P56_RS13445 Genome accession   NZ_CP071522
Coordinates   2765600..2766256 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain UPEC129     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2760600..2771256
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J3P56_RS13415 (J3P56_13415) yecA 2761851..2762516 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  J3P56_RS13435 (J3P56_13435) pgsA 2763166..2763714 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  J3P56_RS13440 (J3P56_13440) uvrC 2763771..2765603 (-) 1833 WP_001283418.1 excinuclease ABC subunit UvrC Machinery gene
  J3P56_RS13445 (J3P56_13445) letA 2765600..2766256 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  J3P56_RS13450 (J3P56_13450) yecU 2766552..2766728 (+) 177 WP_001307856.1 protein YecU -
  J3P56_RS13455 (J3P56_13455) yecF 2766715..2766939 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  J3P56_RS13460 (J3P56_13460) sdiA 2767007..2767729 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  J3P56_RS13465 (J3P56_13465) tcyN 2767959..2768711 (-) 753 WP_001273001.1 L-cystine ABC transporter ATP-binding protein TcyN -
  J3P56_RS13470 (J3P56_13470) tcyL 2768708..2769376 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  J3P56_RS13475 (J3P56_13475) dcyD 2769391..2770377 (-) 987 WP_001128237.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=477536 J3P56_RS13445 WP_000611328.1 2765600..2766256(-) (letA) [Escherichia coli strain UPEC129]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=477536 J3P56_RS13445 WP_000611328.1 2765600..2766256(-) (letA) [Escherichia coli strain UPEC129]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482