Detailed information NTG0477257

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: H7791_RS03485
• Genome accession: NZ_CP060644
• Coordinates: 697480..698709 (+)
• Length: 409 a.a.
• NCBI ID: WP_136038267.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY1309
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 692480..703709

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7791_RS03465 (H7791_03460)	-	693096..694373 (-)	1278	WP_010922170.1	hydroxymethylglutaryl-CoA reductase, degradative	-
H7791_RS03470 (H7791_03465)	-	694360..695535 (-)	1176	WP_014407506.1	hydroxymethylglutaryl-CoA synthase	-
H7791_RS03475 (H7791_03470)	-	695744..696583 (+)	840	WP_011017679.1	thymidylate synthase	-
H7791_RS03480 (H7791_03475)	-	696663..697160 (+)	498	WP_002984955.1	dihydrofolate reductase	-
H7791_RS03485 (H7791_03480)	clpX	697480..698709 (+)	1230	WP_136038267.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
H7791_RS03490 (H7791_03485)	yihA	698719..699318 (+)	600	WP_023612003.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
H7791_RS03495 (H7791_03490)	-	699466..700209 (+)	744	WP_002984942.1	hypothetical protein	-
H7791_RS03500 (H7791_03495)	-	700267..702366 (-)	2100	WP_031488351.1	AAA family ATPase	-
H7791_RS03505 (H7791_03500)	rpiA	702744..703427 (+)	684	WP_002984936.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45091.60 Da
• Isoelectric Point: 4.6281

>NTDB_id=477257 H7791_RS03485 WP_136038267.1 697480..698709(+) (clpX) [Streptococcus pyogenes strain TSPY1309]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLKTSDLIRI
LTEPRNALVKQYQALLSYDGVELEFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=477257 H7791_RS03485 WP_136038267.1 697480..698709(+) (clpX) [Streptococcus pyogenes strain TSPY1309]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTTAAAACATCAGATTTGATTCGAATC
TTAACAGAGCCAAGGAATGCTCTTGTCAAGCAATATCAGGCCCTTCTTTCCTATGATGGGGTTGAATTAGAATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATCGAAGAAA
CGATGTTAGACATCATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	89.242	100	0.892
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575