Detailed information NTG0477258

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: H7791_RS04355
• Genome accession: NZ_CP060644
• Coordinates: 876696..877532 (+)
• Length: 278 a.a.
• NCBI ID: WP_111693218.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY1309
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 871696..882532

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7791_RS04325 (H7791_04330)	-	872250..872618 (+)	369	WP_010922310.1	hypothetical protein	-
H7791_RS04330 (H7791_04335)	-	872668..873579 (-)	912	WP_047235287.1	diacylglycerol/lipid kinase family protein	-
H7791_RS04335 (H7791_04340)	trhA	873696..874346 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
H7791_RS04340 (H7791_04345)	-	874343..874783 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
H7791_RS04345 (H7791_04350)	ylqF	875002..875850 (+)	849	WP_228635031.1	ribosome biogenesis GTPase YlqF	-
H7791_RS04350 (H7791_04355)	-	875840..876631 (+)	792	WP_011285534.1	ribonuclease HII	-
H7791_RS04355 (H7791_04360)	dprA	876696..877532 (+)	837	WP_111693218.1	DNA-processing protein DprA	Machinery gene
H7791_RS04360 (H7791_04365)	topA	877639..879768 (+)	2130	WP_136116729.1	type I DNA topoisomerase	-
H7791_RS04365 (H7791_04370)	-	879843..880700 (-)	858	Protein_820	LysR family transcriptional regulator	-
H7791_RS04370 (H7791_04375)	-	880740..881306 (+)	567	Protein_821	PTS sugar transporter subunit IIC	-
H7791_RS04375 (H7791_04380)	-	881321..882312 (+)	992	Protein_822	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31073.07 Da
• Isoelectric Point: 9.2565

>NTDB_id=477258 H7791_RS04355 WP_111693218.1 876696..877532(+) (dprA) [Streptococcus pyogenes strain TSPY1309]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=477258 H7791_RS04355 WP_111693218.1 876696..877532(+) (dprA) [Streptococcus pyogenes strain TSPY1309]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	100	0.568
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367