Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   H1R75_RS09880 Genome accession   NZ_CP059471
Coordinates   1749969..1750691 (-) Length   240 a.a.
NCBI ID   WP_235686234.1    Uniprot ID   -
Organism   Streptococcus equinus strain MDC1     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1744969..1755691
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1R75_RS09875 comD/comD3 1745715..1746509 (-) 795 WP_235686232.1 sensor histidine kinase Regulator
  H1R75_RS08835 (H1R75_08835) comD/comD3 1747107..1748489 (-) 1383 WP_235686233.1 GHKL domain-containing protein Regulator
  H1R75_RS08840 (H1R75_08840) - 1748490..1748687 (-) 198 WP_182001376.1 hypothetical protein -
  H1R75_RS08845 (H1R75_08845) - 1748849..1749142 (-) 294 WP_182001377.1 bacteriocin immunity protein -
  H1R75_RS08850 (H1R75_08850) - 1749173..1749478 (-) 306 WP_024344359.1 bacteriocin immunity protein -
  H1R75_RS08855 (H1R75_08855) - 1749498..1749794 (-) 297 WP_182001378.1 DUF3884 family protein -
  H1R75_RS09880 comD/comD1 1749969..1750691 (-) 723 WP_235686234.1 sensor histidine kinase Regulator
  H1R75_RS09885 - 1750676..1751290 (-) 615 WP_235686235.1 hypothetical protein -
  H1R75_RS08865 (H1R75_08865) comE/comE1 1751295..1752026 (-) 732 WP_182001379.1 response regulator transcription factor Regulator
  H1R75_RS08870 (H1R75_08870) - 1752950..1753561 (-) 612 WP_182001380.1 thioredoxin fold domain-containing protein -
  H1R75_RS08875 (H1R75_08875) - 1754698..1755372 (-) 675 WP_182001381.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27308.98 Da        Isoelectric Point: 4.8088

>NTDB_id=469861 H1R75_RS09880 WP_235686234.1 1749969..1750691(-) (comD/comD1) [Streptococcus equinus strain MDC1]
MLVYMNRTYQNKLEKEIASAREQELRSLSAYSKQIEGLYEELRAFRHDYANILASLKEGIEQNDMGIVRHIYDSVLTDSA
DFIQNSKFNIGRLANIDDDAIKSLLSAKFLEAEANHIEVNLEVKDKIGAPAMPLLDYIRILAILCDNAIEAALEAENPAI
TIACFYQDDDYVLIVDNTTKEEQVPVDLIYQKDYSSKGHGRGIGLTTIHQMMRKYPNFTVETDSVAHHFCQTIRIKNTLN

Nucleotide


Download         Length: 723 bp        

>NTDB_id=469861 H1R75_RS09880 WP_235686234.1 1749969..1750691(-) (comD/comD1) [Streptococcus equinus strain MDC1]
ATGCTTGTTTACATGAACCGCACTTACCAAAATAAGCTTGAAAAGGAGATTGCTTCAGCGCGTGAGCAAGAGCTGCGTTC
GCTGTCTGCTTATAGTAAACAGATTGAGGGCTTGTATGAAGAATTACGAGCTTTCAGACATGATTATGCCAATATTTTAG
CCAGTTTGAAAGAGGGCATTGAGCAGAATGATATGGGGATTGTTCGACATATTTATGATTCTGTGTTGACGGATTCAGCT
GATTTTATTCAAAATAGTAAGTTTAACATTGGGCGTTTAGCTAATATCGATGATGATGCGATAAAAAGTTTATTGTCTGC
TAAATTTTTAGAAGCTGAGGCTAATCATATTGAGGTCAATCTTGAAGTTAAAGATAAGATTGGTGCACCTGCAATGCCAC
TTTTAGATTATATTCGTATACTTGCTATTTTATGTGATAATGCGATTGAAGCTGCGCTTGAGGCAGAAAATCCAGCCATT
ACGATTGCTTGTTTTTATCAAGATGATGATTATGTGTTAATTGTGGATAATACGACTAAAGAGGAGCAGGTTCCTGTTGA
TTTGATTTATCAAAAAGATTATTCAAGTAAAGGACATGGTCGAGGTATTGGTCTTACAACGATTCATCAGATGATGCGAA
AATATCCAAATTTCACGGTTGAAACGGATAGTGTGGCTCATCATTTCTGTCAGACGATACGTATTAAAAATACGCTAAAC
TAG

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(135-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus equinus JB1

85.837

97.083

0.833
  comD/comD3 Streptococcus equinus JB1

48.085

97.917

0.471
  comD/comD2 Streptococcus equinus JB1

47.66

97.917

0.467
  comD/blpH Streptococcus mutans UA159

44.492

98.333

0.438