Detailed information NTG0469820

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: H1R75_RS03650
• Genome accession: NZ_CP059471
• Coordinates: 661414..662094 (+)
• Length: 226 a.a.
• NCBI ID: WP_074628861.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain MDC1
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 656414..667094

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1R75_RS03620 (H1R75_03620)	-	656432..657631 (+)	1200	WP_182001696.1	MFS transporter	-
H1R75_RS03625 (H1R75_03625)	-	657662..658528 (+)	867	WP_182001697.1	helix-turn-helix transcriptional regulator	-
H1R75_RS03630 (H1R75_03630)	-	658538..659428 (+)	891	WP_182001698.1	ROK family protein	-
H1R75_RS03635 (H1R75_03635)	-	659443..659718 (-)	276	WP_024344272.1	GIY-YIG nuclease family protein	-
H1R75_RS03640 (H1R75_03640)	-	659693..660454 (-)	762	WP_027967945.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
H1R75_RS03645 (H1R75_03645)	-	660573..661319 (+)	747	WP_024344274.1	lysophospholipid acyltransferase family protein	-
H1R75_RS03650 (H1R75_03650)	comEA	661414..662094 (+)	681	WP_074628861.1	helix-hairpin-helix domain-containing protein	Machinery gene
H1R75_RS03655 (H1R75_03655)	comEC/celB	662087..664318 (+)	2232	WP_182001699.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
H1R75_RS03660 (H1R75_03660)	holA	664386..665423 (+)	1038	WP_182001700.1	DNA polymerase III subunit delta	-
H1R75_RS03665 (H1R75_03665)	sodA	665520..666131 (+)	612	WP_039698404.1	superoxide dismutase SodA	-
H1R75_RS03670 (H1R75_03670)	-	666237..666961 (+)	725	Protein_654	YebC/PmpR family DNA-binding transcriptional regulator	-

Sequence

Protein

• Length: 226 a.a.
• Molecular weight: 24037.89 Da
• Isoelectric Point: 4.4812

>NTDB_id=469820 H1R75_RS03650 WP_074628861.1 661414..662094(+) (comEA) [Streptococcus equinus strain MDC1]
MIEEMKEKILEHKTVASVLGTVLVMLVMFFAWSSMESHKAEVQNDLPALSTSFSASSGETSQPKTVTSASKTESDKIFVD
IKGAVRKEGVYELTSGSRVTDVVKLAGGFTDDADKKSVNLAEKVADEAVIYVARVGEEVTPASTPSQAKNTAASGAQQDA
DSAQINLNTATLEELQTISGIGAKRAQDIIDYRDNNGGFSSVDDLKNVSGIGEKTLEKLKAEVTVD

Nucleotide

• Length: 681 bp

>NTDB_id=469820 H1R75_RS03650 WP_074628861.1 661414..662094(+) (comEA) [Streptococcus equinus strain MDC1]
ATGATTGAAGAGATGAAAGAAAAAATTTTAGAGCATAAAACTGTGGCATCAGTTTTGGGGACAGTTCTTGTTATGCTAGT
GATGTTTTTTGCTTGGTCTAGTATGGAAAGCCACAAAGCTGAAGTGCAAAATGATTTACCAGCATTGAGCACTAGCTTTT
CAGCAAGTAGTGGAGAAACATCTCAGCCAAAAACAGTAACATCTGCTTCAAAAACTGAATCAGATAAGATTTTCGTTGAT
ATTAAAGGTGCCGTCAGAAAAGAAGGTGTTTATGAATTAACATCAGGTAGTCGTGTGACAGATGTGGTCAAATTAGCTGG
CGGCTTTACAGATGATGCGGATAAGAAATCTGTTAATTTAGCTGAAAAAGTAGCGGACGAAGCAGTGATTTACGTGGCAA
GAGTTGGTGAAGAGGTCACACCAGCAAGCACCCCGTCTCAGGCTAAAAATACAGCAGCAAGTGGAGCGCAGCAAGATGCG
GACTCAGCACAAATCAATCTTAATACTGCGACTTTAGAAGAACTTCAGACGATTTCTGGCATCGGTGCCAAGCGTGCTCA
AGACATCATCGATTATCGTGATAACAACGGTGGATTTTCTTCAGTTGATGATTTGAAAAATGTGTCAGGTATTGGTGAGA
AGACTTTAGAAAAACTAAAAGCTGAGGTGACAGTTGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (79-132)

• Helix-hairpin-helix motif (HHH_3) (163-224)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Streptococcus thermophilus LMD-9	47.436	100	0.491
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	45.778	99.558	0.456
comEA/celA/cilE	Streptococcus mitis SK321	45.333	99.558	0.451
comEA/celA/cilE	Streptococcus mitis NCTC 12261	45.333	99.558	0.451
comEA/celA/cilE	Streptococcus pneumoniae Rx1	42.291	100	0.425
comEA/celA/cilE	Streptococcus pneumoniae D39	42.291	100	0.425
comEA/celA/cilE	Streptococcus pneumoniae R6	42.291	100	0.425
comEA	Latilactobacillus sakei subsp. sakei 23K	39.462	98.673	0.389