Detailed information NTG0469821

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: H1R75_RS03655
• Genome accession: NZ_CP059471
• Coordinates: 662087..664318 (+)
• Length: 743 a.a.
• NCBI ID: WP_182001699.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain MDC1
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 657087..669318

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1R75_RS03625 (H1R75_03625)	-	657662..658528 (+)	867	WP_182001697.1	helix-turn-helix transcriptional regulator	-
H1R75_RS03630 (H1R75_03630)	-	658538..659428 (+)	891	WP_182001698.1	ROK family protein	-
H1R75_RS03635 (H1R75_03635)	-	659443..659718 (-)	276	WP_024344272.1	GIY-YIG nuclease family protein	-
H1R75_RS03640 (H1R75_03640)	-	659693..660454 (-)	762	WP_027967945.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
H1R75_RS03645 (H1R75_03645)	-	660573..661319 (+)	747	WP_024344274.1	lysophospholipid acyltransferase family protein	-
H1R75_RS03650 (H1R75_03650)	comEA	661414..662094 (+)	681	WP_074628861.1	helix-hairpin-helix domain-containing protein	Machinery gene
H1R75_RS03655 (H1R75_03655)	comEC/celB	662087..664318 (+)	2232	WP_182001699.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
H1R75_RS03660 (H1R75_03660)	holA	664386..665423 (+)	1038	WP_182001700.1	DNA polymerase III subunit delta	-
H1R75_RS03665 (H1R75_03665)	sodA	665520..666131 (+)	612	WP_039698404.1	superoxide dismutase SodA	-
H1R75_RS03670 (H1R75_03670)	-	666237..666961 (+)	725	Protein_654	YebC/PmpR family DNA-binding transcriptional regulator	-
H1R75_RS03675 (H1R75_03675)	queA	667008..668036 (-)	1029	WP_182001701.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
H1R75_RS03680 (H1R75_03680)	-	668196..668702 (+)	507	WP_021141923.1	VIT1/CCC1 transporter family protein	-

Sequence

Protein

• Length: 743 a.a.
• Molecular weight: 83912.57 Da
• Isoelectric Point: 9.6343

>NTDB_id=469821 H1R75_RS03655 WP_182001699.1 662087..664318(+) (comEC/celB) [Streptococcus equinus strain MDC1]
MIKHFPIKPIQLAFLLILVYYFCFLKVFWCIVLLLLALICLWKNYGSKKLWQTLIILMYFASFISFKNQQAEQADKVASA
HLSKIQMIPDTISVNGDLLSFRGKEAGQTYQVFYTLKSEKEQQFFKSLNQTLVLSGEIDLEKATPQRNFGGFDYRTYLKH
EGIYRIGNLSSIVGMRRQTSLTLAERLHDLRRKAIVSIQQNFPAPMQHYMTGLLFGYLDKSFDEMSDIYTSLGIIHLFAL
SGMQVGFFVGVFRYFFLRLGLRRDYVDILQIPFSLVYAGLTGFSVSVVRSLIQSGLGNIGVKRLDNLALTMMILFCIMPN
FLLTTGGILSFTYAFILSFIDFVELESYQKKIVECLAISLGSLPILIYFFSVFQPMSIILTAIFSLAFDTLMLPVLSVVF
LLSPLVRLSIFNSFFIVLEDVIKLTMNFLGGPIVFGKPSIGILVFLLFSLGILYDYRQKRKVMIFLVSLVALLFFQIKHP
LENEVTVVDIGQGDSIFVRDVKGRTLLIDVGGKVSFSQKEGWQERLSDSNADRTLIPYLNSRGVGKIDQLVLTHTDTDHM
GDMLEVAKQVKIGEVLVSQGSLKKPDFVAKLKAMKTRVRVVSAGDSLPIMGSSLQVLYPIRVGDGSNNDSVVLYGKLLGK
NFLFTGDLEEEGEREVMATYPNLPVDVLKAGHHGSKGSSSPAFLAHISPQIALISAGQNNRYKHPHQETLERFRAQNMTI
YRTDEQGAIRFRGLNHWKIETVR

Nucleotide

• Length: 2232 bp

>NTDB_id=469821 H1R75_RS03655 WP_182001699.1 662087..664318(+) (comEC/celB) [Streptococcus equinus strain MDC1]
TTGATTAAACATTTTCCCATTAAGCCAATTCAATTGGCTTTTTTGCTCATTCTCGTTTATTATTTTTGCTTTTTGAAGGT
CTTTTGGTGCATAGTCCTCCTTTTATTAGCCCTGATCTGCTTATGGAAAAACTACGGTTCTAAAAAATTGTGGCAAACCT
TGATAATTCTGATGTACTTTGCTAGTTTTATTAGTTTTAAAAATCAGCAAGCAGAGCAAGCTGACAAAGTAGCGTCAGCT
CATTTATCAAAAATCCAGATGATTCCAGACACGATTTCGGTCAATGGTGACTTGCTGTCTTTTAGAGGAAAGGAGGCTGG
ACAGACTTATCAGGTCTTTTATACTTTGAAGTCAGAAAAGGAGCAGCAATTTTTTAAAAGTCTTAATCAAACGCTTGTCT
TGTCTGGTGAGATTGACTTAGAGAAAGCAACACCTCAGCGTAATTTTGGTGGGTTTGACTATCGGACTTACTTGAAACAT
GAAGGTATTTATCGCATTGGAAATCTTTCTTCAATTGTTGGGATGAGACGCCAAACTTCTTTGACTTTGGCTGAGCGACT
GCATGATTTGCGGCGAAAAGCTATTGTTAGCATCCAGCAAAATTTTCCAGCACCCATGCAACATTATATGACTGGGCTTT
TGTTTGGTTATCTGGATAAATCTTTTGATGAAATGAGCGATATTTACACGAGTTTGGGGATTATTCACCTCTTTGCTCTT
TCCGGTATGCAGGTTGGCTTTTTTGTCGGTGTTTTTCGCTATTTCTTTTTGCGACTTGGCTTAAGGCGTGATTATGTTGA
TATTCTTCAAATTCCTTTTTCGCTTGTATATGCTGGTTTGACAGGATTTTCAGTGTCAGTTGTCCGAAGTCTCATTCAGT
CAGGTTTAGGCAATATTGGCGTTAAGCGACTTGATAATCTTGCTTTGACCATGATGATTCTTTTCTGCATTATGCCTAAT
TTCCTGCTGACAACGGGAGGCATTTTGTCATTTACTTATGCCTTTATTCTAAGTTTTATTGATTTTGTGGAACTTGAAAG
TTATCAGAAGAAAATTGTAGAATGCTTGGCAATTTCATTAGGTAGCTTACCAATTTTGATTTACTTTTTTTCAGTTTTTC
AACCGATGTCTATTATTTTGACAGCTATTTTTTCATTGGCATTTGATACGCTTATGTTGCCAGTTCTGTCAGTTGTTTTC
TTGCTTTCGCCACTCGTGAGATTATCAATTTTTAATAGCTTTTTTATCGTTTTAGAAGATGTGATAAAGCTGACTATGAA
TTTCCTTGGTGGTCCGATTGTTTTTGGCAAACCAAGTATTGGTATTTTGGTATTCCTATTATTTAGCTTAGGTATTCTTT
ATGATTACAGACAGAAAAGGAAAGTTATGATTTTTCTTGTCAGCTTAGTAGCTCTGCTATTTTTCCAAATCAAGCATCCG
CTGGAAAACGAAGTGACGGTGGTTGACATTGGGCAGGGAGATAGTATTTTTGTGCGTGATGTCAAAGGGCGTACGCTGTT
AATTGATGTCGGAGGAAAGGTGAGTTTTAGCCAAAAAGAAGGCTGGCAGGAGCGTTTGTCTGACAGTAATGCAGATCGAA
CCTTGATTCCTTATCTCAATAGCCGTGGCGTTGGAAAAATTGACCAGCTGGTTCTGACGCACACGGATACTGACCACATG
GGAGATATGTTGGAAGTGGCAAAGCAGGTGAAAATTGGTGAAGTTTTGGTTAGTCAAGGAAGTTTGAAAAAGCCAGATTT
TGTAGCAAAGCTGAAAGCCATGAAGACTAGAGTTCGCGTAGTTTCTGCTGGAGATAGTCTGCCGATTATGGGAAGTAGCT
TGCAAGTGCTTTATCCTATTAGAGTTGGCGATGGTTCTAATAATGATTCGGTGGTGTTGTATGGCAAGCTTCTTGGTAAA
AATTTTCTGTTTACAGGAGATTTGGAAGAAGAAGGTGAGCGTGAGGTGATGGCGACTTATCCTAATTTGCCAGTTGATGT
TTTAAAAGCGGGACACCATGGTTCAAAAGGGTCATCAAGCCCGGCATTTCTAGCTCATATTTCACCGCAAATTGCTTTGA
TTTCTGCTGGACAAAATAACCGATACAAACATCCTCACCAAGAAACGCTTGAACGCTTCCGAGCACAAAACATGACCATT
TACCGCACAGACGAACAAGGCGCTATCCGCTTTAGAGGATTAAACCACTGGAAAATTGAGACGGTAAGGTGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (213-459)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-696)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	52.156	99.865	0.521
comEC/celB	Streptococcus mitis NCTC 12261	51.617	99.865	0.515
comEC/celB	Streptococcus pneumoniae TIGR4	50.875	100	0.509
comEC/celB	Streptococcus pneumoniae Rx1	50.336	100	0.503
comEC/celB	Streptococcus pneumoniae D39	50.336	100	0.503
comEC/celB	Streptococcus pneumoniae R6	50.336	100	0.503
comEC	Lactococcus lactis subsp. cremoris KW2	47.376	100	0.474