NTDB

Overview

Name	comEA/celA/cilE	Type	Machinery gene
Locus tag	SSU16085_RS08495	Genome accession	NZ_CP058740
Coordinates	1755613..1756275 (-)	Length	220 a.a.
NCBI ID	WP_079394055.1	Uniprot ID	A0A0Z8ST93
Organism	Streptococcus suis strain 16085/3b
Function	dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1750613..1761275

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSU16085_RS08475 (SSU16085_01725)	-	1751491..1752318 (-)	828	WP_002935354.1	hypothetical protein	-
SSU16085_RS08480 (SSU16085_01726)	-	1752412..1753068 (-)	657	WP_002935353.1	CBS domain-containing protein	-
SSU16085_RS08485 (SSU16085_01727)	-	1753247..1753390 (-)	144	WP_002935351.1	transposase	-
SSU16085_RS08490 (SSU16085_01728)	comEC/celB	1753392..1755629 (-)	2238	WP_043033064.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SSU16085_RS08495 (SSU16085_01729)	comEA/celA/cilE	1755613..1756275 (-)	663	WP_079394055.1	helix-hairpin-helix domain-containing protein	Machinery gene
SSU16085_RS08500 (SSU16085_01730)	-	1756346..1757092 (-)	747	WP_014735985.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
SSU16085_RS08505 (SSU16085_01731)	-	1757238..1758683 (+)	1446	WP_013730320.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
SSU16085_RS08510 (SSU16085_01732)	-	1758835..1759635 (+)	801	WP_013730319.1	ABC transporter ATP-binding protein	-
SSU16085_RS08515 (SSU16085_01733)	-	1759632..1760561 (+)	930	WP_009909659.1	ABC transporter substrate-binding protein	-

Sequence

Protein

Download Length: 220 a.a. Molecular weight: 23368.04 Da Isoelectric Point: 4.0751

                                >NTDB_id=465162 SSU16085_RS08495 WP_079394055.1 1755613..1756275(-) (comEA/celA/cilE) [Streptococcus suis strain 16085/3b]

MDTMKTYIEMLKEYKWQIALPAVAGLLMATFLIFSQPAKSDQTGLTDFPQTAQTSSSSDLVEETSTEVSEEPSQLVVDVK

GAVEKPGLYTLEAGARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVASTNASSAMSQEEKNTSLVN

LNTATEADLQTISGIGAKRATDIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVD

Nucleotide

Download Length: 663 bp

                                >NTDB_id=465162 SSU16085_RS08495 WP_079394055.1 1755613..1756275(-) (comEA/celA/cilE) [Streptococcus suis strain 16085/3b]

ATGGATACGATGAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAGATTGCTCTGCCTGCAGTGGCTGGCTTGCT

AATGGCGACGTTCTTAATATTCAGCCAACCAGCAAAGTCTGACCAGACAGGCCTGACAGACTTTCCACAGACCGCACAAA

CTTCTAGCAGCTCTGACTTGGTCGAGGAAACCAGTACAGAAGTAAGTGAGGAACCCAGTCAGCTAGTCGTTGATGTCAAA

GGAGCGGTGGAAAAACCAGGGCTCTACACCTTAGAAGCTGGTGCGCGTGTTAATGATGCAGTTGAAGCAGCTGGCGGCTT

GACCAGTCAGGCAGACCCAAAGTCTATCAATCTGGCTCAGAAGCTCAGCGATGAGGCGGTGGTCTATGTGGCCAGCAAGG

ACGAAAACATCTCGGTGGTGGCCAGCACGAATGCCAGCTCTGCTATGTCCCAAGAAGAAAAAAACACCAGTCTAGTCAAT

CTGAATACGGCGACCGAGGCTGACTTGCAGACCATTTCTGGTATTGGTGCCAAGCGAGCGACGGACATTATCGCCTATCG

TGAGGCCAACGGTGGCTTCAAGTCGGTGGATGACCTCAACAATGTTTCGGGCATTGGCGACAAGACTATGGAAAGCATTC

GACCTTATGTTACGGTCGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(155-218)

SLBB domain (SLBB)

(76-130)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A0Z8ST93

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	48.649	100	0.491
comEA/celA/cilE	Streptococcus mitis NCTC 12261	48.43	100	0.491
comEA/celA/cilE	Streptococcus pneumoniae Rx1	48.43	100	0.491
comEA/celA/cilE	Streptococcus pneumoniae D39	48.43	100	0.491
comEA/celA/cilE	Streptococcus pneumoniae R6	48.43	100	0.491
comEA/celA/cilE	Streptococcus mitis SK321	46.847	100	0.473
comEA	Streptococcus thermophilus LMD-9	59.259	73.636	0.436
comEA	Lactococcus lactis subsp. cremoris KW2	37.391	100	0.391

Detailed information NTG0465162