Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   HW271_RS04995 Genome accession   NZ_CP058258
Coordinates   1006746..1007450 (-) Length   234 a.a.
NCBI ID   WP_178895096.1    Uniprot ID   -
Organism   Streptococcus sp. oral taxon 061 strain F0704     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1001746..1012450
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HW271_RS04975 (HW271_04975) - 1002380..1004098 (+) 1719 WP_178895092.1 phospho-sugar mutase -
  HW271_RS04980 (HW271_04980) - 1004210..1004557 (+) 348 WP_178895093.1 PedC/BrcD family bacteriocin maturation disulfide isomerase -
  HW271_RS04985 (HW271_04985) vicX 1004593..1005402 (-) 810 WP_178895094.1 MBL fold metallo-hydrolase Regulator
  HW271_RS04990 (HW271_04990) micB 1005395..1006753 (-) 1359 WP_178895095.1 cell wall metabolism sensor histidine kinase VicK Regulator
  HW271_RS04995 (HW271_04995) micA 1006746..1007450 (-) 705 WP_178895096.1 response regulator YycF Regulator
  HW271_RS05000 (HW271_05000) mutY 1007518..1008675 (-) 1158 WP_178895097.1 A/G-specific adenine glycosylase -
  HW271_RS05005 (HW271_05005) - 1008846..1011125 (+) 2280 WP_178895098.1 Xaa-Pro dipeptidyl-peptidase -
  HW271_RS05010 (HW271_05010) - 1011175..1011336 (-) 162 WP_006148428.1 hypothetical protein -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26980.89 Da        Isoelectric Point: 4.6834

>NTDB_id=463222 HW271_RS04995 WP_178895096.1 1006746..1007450(-) (micA) [Streptococcus sp. oral taxon 061 strain F0704]
MKKILIVDDEKPISDIIKFNMTKEGYEVITAFNGREAIELFEAEKPDIIILDLMLPEIDGLEVAKTIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTELVAVDNQEEDTKLQSLQIGDLEILPDAYVAKKYGEELDLT
HREFELLHHLASHLGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=463222 HW271_RS04995 WP_178895096.1 1006746..1007450(-) (micA) [Streptococcus sp. oral taxon 061 strain F0704]
ATGAAAAAAATATTGATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACCAAGGAAGGCTATGA
AGTTATTACAGCCTTTAATGGACGTGAAGCGATTGAACTGTTTGAAGCTGAAAAACCTGATATTATTATTTTGGACTTGA
TGCTTCCAGAAATTGATGGTCTTGAAGTGGCTAAAACAATTCGCAAGACAAGCAGTGTTCCGATTATCATGCTTTCAGCA
AAAGACAGTGAGTTTGATAAGGTTATTGGTCTTGAACTTGGCGCGGATGATTATGTGACCAAGCCATTTTCAAACCGTGA
GCTACAAGCGCGTGTTAAGGCACTTCTTCGTCGTACGGAGTTAGTAGCAGTGGATAACCAAGAGGAAGATACTAAATTGC
AAAGTCTTCAAATTGGGGATTTAGAGATTCTTCCAGATGCTTATGTAGCCAAAAAATATGGAGAAGAATTGGACTTAACT
CATAGAGAGTTTGAGTTGTTGCATCACTTAGCTTCGCATCTAGGTCAAGTTATTACTCGTGAACATCTCCTTGAGACTGT
TTGGGGTTATGATTATTTTGGTGATGTTCGTACTGTCGATGTCACTATTAGACGTCTACGTGAGAAGATTGAAGACACAC
CAAGTAGACCTGAATATATCTTAACTCGTCGTGGTGTTGGTTATTACATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

91.416

99.573

0.91
  vicR Streptococcus mutans UA159

79.149

100

0.795
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.478

98.291

0.427
  scnR Streptococcus mutans UA159

37.069

99.145

0.368