Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   HW271_RS04990 Genome accession   NZ_CP058258
Coordinates   1005395..1006753 (-) Length   452 a.a.
NCBI ID   WP_178895095.1    Uniprot ID   A0A7H8ZA68
Organism   Streptococcus sp. oral taxon 061 strain F0704     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1000395..1011753
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HW271_RS04975 (HW271_04975) - 1002380..1004098 (+) 1719 WP_178895092.1 phospho-sugar mutase -
  HW271_RS04980 (HW271_04980) - 1004210..1004557 (+) 348 WP_178895093.1 PedC/BrcD family bacteriocin maturation disulfide isomerase -
  HW271_RS04985 (HW271_04985) vicX 1004593..1005402 (-) 810 WP_178895094.1 MBL fold metallo-hydrolase Regulator
  HW271_RS04990 (HW271_04990) micB 1005395..1006753 (-) 1359 WP_178895095.1 cell wall metabolism sensor histidine kinase VicK Regulator
  HW271_RS04995 (HW271_04995) micA 1006746..1007450 (-) 705 WP_178895096.1 response regulator YycF Regulator
  HW271_RS05000 (HW271_05000) mutY 1007518..1008675 (-) 1158 WP_178895097.1 A/G-specific adenine glycosylase -
  HW271_RS05005 (HW271_05005) - 1008846..1011125 (+) 2280 WP_178895098.1 Xaa-Pro dipeptidyl-peptidase -
  HW271_RS05010 (HW271_05010) - 1011175..1011336 (-) 162 WP_006148428.1 hypothetical protein -

Sequence

Protein


Download         Length: 452 a.a.        Molecular weight: 52009.38 Da        Isoelectric Point: 4.6418

>NTDB_id=463221 HW271_RS04990 WP_178895095.1 1005395..1006753(-) (micB) [Streptococcus sp. oral taxon 061 strain F0704]
MIEVIRQTILTRDFVFVLILIGFIMLVSFLLLEGRRDNIRLKQLNQKIKDLIAGDYSQVLDMQGNTEITNITNNLNDLSE
VIRLTQENLEQESKRLHSILSYMTDGVLATNRRGQITMINDMAKRQLGVVSDEALNQNILELLKIEDEYELRDLITQSPE
LMIYSQNVNGEYISLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALY
EPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKIRAQDQEKKYELVRDYPITSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDDQMILSISDQGLGIPKEDLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIIKQHNGFIWAKSEYDKGSTFTIVLPYDNDAVKEEVWEDEVEDKNE

Nucleotide


Download         Length: 1359 bp        

>NTDB_id=463221 HW271_RS04990 WP_178895095.1 1005395..1006753(-) (micB) [Streptococcus sp. oral taxon 061 strain F0704]
ATGATTGAAGTAATTAGACAAACAATTTTAACCAGAGATTTCGTCTTTGTACTCATTTTAATTGGTTTTATCATGCTTGT
TAGTTTTCTCTTGCTTGAAGGCCGTAGAGATAATATCCGACTCAAACAGTTAAATCAAAAGATTAAAGATTTAATTGCTG
GTGATTATTCTCAAGTACTGGATATGCAGGGGAATACTGAAATCACTAACATTACGAATAACTTAAATGATTTGTCTGAA
GTTATTCGTCTAACTCAGGAAAACCTTGAGCAGGAAAGTAAAAGATTGCATAGTATTTTGTCATATATGACAGATGGGGT
TCTTGCAACAAATCGTCGTGGTCAAATCACGATGATTAACGATATGGCTAAGAGGCAACTTGGCGTCGTAAGTGATGAAG
CATTAAATCAGAACATTTTAGAGTTGCTCAAGATTGAAGATGAGTACGAGCTTAGAGACTTAATAACTCAAAGTCCTGAA
TTGATGATTTATTCCCAAAATGTTAATGGAGAGTATATCAGTTTGCGTGTGCGTTTTGCCTTGATTCGTAGAGAATCTGG
TTTTATCTCCGGTTTGGTAGCAGTCCTACATGATACGACTGAACAAGAGAAGGAAGAGCGCGAGAGAAGGCTTTTCGTTT
CAAACGTTAGTCATGAATTGCGAACTCCTTTGACCAGTGTAAAATCTTATCTTGAGGCCTTGGATGAGGGTGCATTATAT
GAACCTGTTGCTCCTGATTTTATCAAAGTATCTTTAGATGAGACCAACCGTATGATGCGAATGGTGACGGACCTCTTGCA
TCTTTCGCGTATTGATAATGCAACTAGCCATTTAGATGTTGAATTGATTAACTTTACAGCTTTCATTACGTTTATCCTAA
ACCGTTTCGATAAGATACGAGCCCAGGATCAAGAAAAGAAATACGAGTTGGTTCGTGATTATCCCATTACATCGGTCTGG
ATTGAAATTGATACAGACAAGATGACTCAGGTAATCGATAATATTCTTAACAATGCCATCAAGTATTCCCCTGATGGTGG
GAAAATTACGGTTAGCATGAAAACCACTGATGACCAGATGATTTTATCCATTTCTGATCAAGGACTTGGAATTCCTAAAG
AAGATTTACCGAAGATTTTTGACCGTTTCTACAGGGTTGATAAGGCTAGAAGTCGTGCCCAAGGTGGGACTGGTTTAGGT
CTTGCTATAGCAAAAGAAATCATCAAGCAACACAATGGATTTATCTGGGCCAAGAGTGAATATGACAAGGGTTCAACCTT
TACCATTGTTCTTCCTTATGATAATGATGCTGTGAAAGAAGAAGTATGGGAGGATGAAGTAGAAGACAAGAATGAGTGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(95-198)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7H8ZA68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

85.649

97.124

0.832
  vicK Streptococcus mutans UA159

71.533

90.929

0.65