Detailed information NTG0460894

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: JM964_RS05560
• Genome accession: NZ_CP068708
• Coordinates: 1146719..1147390 (-)
• Length: 223 a.a.
• NCBI ID: WP_014637852.1
• Uniprot ID: -
• Organism: Streptococcus suis strain ID33329
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1141719..1152390

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JM964_RS05535 (JM964_05535)	-	1141876..1142466 (-)	591	WP_024376492.1	class I SAM-dependent methyltransferase	-
JM964_RS05540 (JM964_05540)	coaA	1142575..1143495 (+)	921	WP_024410470.1	type I pantothenate kinase	-
JM964_RS05545 (JM964_05545)	rpsT	1143554..1143802 (+)	249	WP_012027069.1	30S ribosomal protein S20	-
JM964_RS05550 (JM964_05550)	-	1144017..1145246 (-)	1230	WP_024401459.1	transglutaminase domain-containing protein	-
JM964_RS05555 (JM964_05555)	ciaH	1145347..1146726 (-)	1380	WP_024401460.1	sensor histidine kinase	Regulator
JM964_RS05560 (JM964_05560)	ciaR	1146719..1147390 (-)	672	WP_014637852.1	response regulator transcription factor	Regulator
JM964_RS05565 (JM964_05565)	-	1147584..1147964 (-)	381	WP_024401461.1	hypothetical protein	-
JM964_RS05570 (JM964_05570)	phoU	1148130..1148786 (-)	657	WP_002937611.1	phosphate signaling complex protein PhoU	-
JM964_RS05575 (JM964_05575)	pstB	1148815..1149573 (-)	759	WP_002937614.1	phosphate ABC transporter ATP-binding protein PstB	-
JM964_RS05580 (JM964_05580)	pstB	1149585..1150388 (-)	804	WP_002937615.1	phosphate ABC transporter ATP-binding protein PstB	-
JM964_RS05585 (JM964_05585)	pstA	1150413..1151300 (-)	888	WP_002937616.1	phosphate ABC transporter permease PstA	-
JM964_RS05590 (JM964_05590)	pstC	1151290..1152207 (-)	918	WP_002937619.1	phosphate ABC transporter permease subunit PstC	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 25245.83 Da
• Isoelectric Point: 4.2183

>NTDB_id=460894 JM964_RS05560 WP_014637852.1 1146719..1147390(-) (ciaR) [Streptococcus suis strain ID33329]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGIYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTYGDVTVDLSTNSTTVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

• Length: 672 bp

>NTDB_id=460894 JM964_RS05560 WP_014637852.1 1146719..1147390(-) (ciaR) [Streptococcus suis strain ID33329]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTGGATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGTGAAGAGGGTATTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT
TGCCTGAAAAAGATGGCTTCCAAGTTTTGAAAGAGTTACGTGAAAAAGGTGTTACGACACCAGTTCTGATTACAACAGCC
AAGGAAAGTTTAGAGGATAAAGGCCATGGTTTTGAATTGGGAGCTGATGACTACTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACTTATGGGGACGTGACCG
TTGACTTATCGACAAACTCTACAACTGTAAATGGCGAAGAAGTTGAATTGCTAGGAAAAGAATTCGATCTACTAGTCTAC
TTCTTGCAAAATCAAAATGTTATCTTGCCAAAAACTCAAATTTTTGACCGTATTTGGGGATTTGACAGTGACACTACTAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACCTTCGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGGTACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

• Response regulator receiver domain (Response_reg) (4-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	90.135	100	0.901
ciaR	Streptococcus pneumoniae Rx1	88.789	100	0.888
ciaR	Streptococcus pneumoniae D39	88.789	100	0.888
ciaR	Streptococcus pneumoniae R6	88.789	100	0.888
ciaR	Streptococcus pneumoniae TIGR4	88.789	100	0.888
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.053	100	0.386
vicR	Streptococcus mutans UA159	35.47	100	0.372
covR	Streptococcus salivarius strain HSISS4	36.283	100	0.368