NTDB

Overview

Name	clpP	Type	Regulator
Locus tag	I6J12_RS01345	Genome accession	NZ_CP068060
Coordinates	276071..276685 (+)	Length	204 a.a.
NCBI ID	WP_223349572.1	Uniprot ID	-
Organism	Streptococcus anginosus strain FDAARGOS_1155
Function	degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 271071..281685

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J12_RS01335 (I6J12_01335)	mgtA	272602..275256 (+)	2655	WP_003033895.1	magnesium-translocating P-type ATPase	-
I6J12_RS01340 (I6J12_01340)	upp	275354..275983 (+)	630	WP_020999498.1	uracil phosphoribosyltransferase	-
I6J12_RS01345 (I6J12_01345)	clpP	276071..276685 (+)	615	WP_223349572.1	ATP-dependent Clp protease proteolytic subunit	Regulator
I6J12_RS01350 (I6J12_01350)	-	276776..277045 (+)	270	WP_003033867.1	YlbG family protein	-
I6J12_RS01355 (I6J12_01355)	-	277071..278006 (-)	936	WP_020999450.1	IS30 family transposase	-
I6J12_RS01360 (I6J12_01360)	-	278190..279353 (+)	1164	WP_003034337.1	ABC transporter substrate-binding protein	-
I6J12_RS01365 (I6J12_01365)	-	279745..280614 (+)	870	WP_018543650.1	branched-chain amino acid ABC transporter permease	-
I6J12_RS01370 (I6J12_01370)	-	280618..281568 (+)	951	WP_003034346.1	branched-chain amino acid ABC transporter permease	-

Sequence

Protein

Download Length: 204 a.a. Molecular weight: 22503.62 Da Isoelectric Point: 4.6199

                                >NTDB_id=458771 I6J12_RS01345 WP_223349572.1 276071..276685(+) (clpP) [Streptococcus anginosus strain FDAARGOS_1155]

MSDEKENTMIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYINTPGGSVSAG

LAIVDTMNFIKSDVQTIVMGMAASMGTIIASSGAKGKRFMLPNAEYLIHQPMGGTGSGTQQTDMAIAAEHLLKTRNNLEK

ILADNSGKTIKQVHKDAERDYWMSAQETLDYGFIDEIMANNNLN

Nucleotide

Download Length: 615 bp

                                >NTDB_id=458771 I6J12_RS01345 WP_223349572.1 276071..276685(+) (clpP) [Streptococcus anginosus strain FDAARGOS_1155]

ATATCAGATGAAAAGGAGAATACAATGATTCCTGTAGTTATTGAACAAACAAGTCGTGGGGAACGTTCCTACGATATTTA

CTCACGCTTATTAAAAGATCGCATTATTATGCTGACAGGTCCTGTTGAGGACAATATGGCTAATTCTATTATTGCGCAAT

TGCTTTTCCTTGATGCACAAGATAATACTAAAGATATTTATCTTTACATCAATACGCCAGGTGGTTCTGTATCGGCTGGT

CTAGCGATTGTGGATACCATGAACTTCATCAAGTCAGATGTCCAAACAATTGTCATGGGGATGGCTGCTTCCATGGGAAC

CATTATTGCTTCAAGTGGTGCTAAAGGCAAGCGCTTCATGTTGCCGAATGCAGAATACCTGATTCATCAGCCAATGGGCG

GAACTGGTAGCGGTACGCAGCAAACCGATATGGCGATTGCAGCTGAGCATTTGCTGAAAACACGGAATAACTTGGAGAAG

ATCCTTGCGGATAATTCAGGGAAAACCATTAAGCAAGTACATAAAGACGCAGAACGCGATTATTGGATGAGCGCTCAAGA

AACCTTGGATTATGGCTTCATTGATGAAATCATGGCAAATAATAATTTAAACTAA

Domains

Predicted by InterProScan.

Clp protease (CLP_protease)

(19-200)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
clpP	Streptococcus mutans UA159	89.655	99.51	0.892
clpP	Streptococcus thermophilus LMD-9	92.308	95.588	0.882
clpP	Streptococcus thermophilus LMG 18311	92.308	95.588	0.882
clpP	Streptococcus pyogenes JRS4	91.795	95.588	0.877
clpP	Streptococcus pyogenes MGAS315	91.795	95.588	0.877
clpP	Streptococcus pneumoniae D39	90.816	96.078	0.873
clpP	Streptococcus pneumoniae Rx1	90.816	96.078	0.873
clpP	Streptococcus pneumoniae R6	90.816	96.078	0.873
clpP	Streptococcus pneumoniae TIGR4	90.816	96.078	0.873
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	86.667	95.588	0.828
clpP	Lactococcus lactis subsp. cremoris KW2	86.154	95.588	0.824
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.995	94.608	0.539
clpP	Bacillus subtilis subsp. subtilis str. 168	56.25	94.118	0.529

Detailed information NTG0458771