Detailed information NTG0458244

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: JJN14_RS07185
• Genome accession: NZ_CP067992
• Coordinates: 1428859..1429449 (-)
• Length: 196 a.a.
• NCBI ID: WP_000613475.1
• Uniprot ID: A0A2I1UFF8
• Organism: Streptococcus mitis strain S022-V7-A3
• Function: degradation of ComX; degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1423859..1434449

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JJN14_RS07160 (JJN14_07160)	-	1424556..1425320 (-)	765	WP_201058270.1	ABC transporter ATP-binding protein	-
JJN14_RS07165 (JJN14_07165)	-	1425320..1426276 (-)	957	WP_000662290.1	branched-chain amino acid ABC transporter permease	-
JJN14_RS07170 (JJN14_07170)	-	1426280..1427149 (-)	870	WP_000941421.1	branched-chain amino acid ABC transporter permease	-
JJN14_RS07175 (JJN14_07175)	-	1427265..1428425 (-)	1161	WP_070478656.1	ABC transporter substrate-binding protein	-
JJN14_RS07180 (JJN14_07180)	-	1428493..1428780 (-)	288	WP_049492230.1	YlbG family protein	-
JJN14_RS07185 (JJN14_07185)	clpP	1428859..1429449 (-)	591	WP_000613475.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
JJN14_RS07190 (JJN14_07190)	upp	1429623..1430252 (-)	630	WP_201058271.1	uracil phosphoribosyltransferase	-
JJN14_RS07195 (JJN14_07195)	-	1430341..1430808 (-)	468	WP_000136976.1	deoxycytidylate deaminase	-
JJN14_RS07200 (JJN14_07200)	-	1430827..1431384 (-)	558	WP_201058272.1	TetR/AcrR family transcriptional regulator	-
JJN14_RS07205 (JJN14_07205)	-	1431509..1432354 (+)	846	WP_201058273.1	DegV family protein	-
JJN14_RS07210 (JJN14_07210)	-	1432413..1433585 (+)	1173	WP_201058274.1	NAD(P)/FAD-dependent oxidoreductase	-
JJN14_RS07215 (JJN14_07215)	-	1433634..1434155 (+)	522	WP_201058275.1	DUF1697 domain-containing protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21340.32 Da
• Isoelectric Point: 4.4910

>NTDB_id=458244 JJN14_RS07185 WP_000613475.1 1428859..1429449(-) (clpP) [Streptococcus mitis strain S022-V7-A3]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SIEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN

Nucleotide

• Length: 591 bp

>NTDB_id=458244 JJN14_RS07185 WP_000613475.1 1428859..1429449(-) (clpP) [Streptococcus mitis strain S022-V7-A3]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCCTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATCATGCTGACAGGCCCAGTTGAAGACAATATGGCCAACTCAGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACAAAAGATATTTACCTATATGTCAACACACCTGGTGGTTCCGTTTCAGCTGGTTTGGCAATCGTTGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACCATCGTTATGGGAATGGCTGCATCTATGGGTACAGTCATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATCCACCAACCAATGGGTGGTACAGGTGGTGGTACTCAACAAA
CTGATATGGCTATCGCTGCAGAACACTTGCTTAAAACTCGTAACACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATTGAAAAAGTCCATGCAGATGCAGAACGCGATAACTGGATGAGTGCTCAAGAAACACTTGAATATGGCTTTATTGA
TGAAATCATGGCCAACAATTCATTGAACTAA

Domains

Predicted by InterProScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A2I1UFF8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pneumoniae Rx1	99.49	100	0.995
clpP	Streptococcus pneumoniae D39	99.49	100	0.995
clpP	Streptococcus pneumoniae R6	99.49	100	0.995
clpP	Streptococcus pneumoniae TIGR4	99.49	100	0.995
clpP	Streptococcus thermophilus LMG 18311	93.333	99.49	0.929
clpP	Streptococcus thermophilus LMD-9	93.333	99.49	0.929
clpP	Streptococcus pyogenes JRS4	91.282	99.49	0.908
clpP	Streptococcus pyogenes MGAS315	91.282	99.49	0.908
clpP	Streptococcus mutans UA159	86.224	100	0.862
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	85.128	99.49	0.847
clpP	Lactococcus lactis subsp. cremoris KW2	84.615	99.49	0.842
clpP	Bacillus subtilis subsp. subtilis str. 168	58.854	97.959	0.577
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.031	98.469	0.571