Detailed information NTG0453756

Bioinformatically predicted

Overview

• Name: comR/comR1
• Type: Regulator
• Locus tag: I6I02_RS03235
• Genome accession: NZ_CP066093
• Coordinates: 738018..738926 (-)
• Length: 302 a.a.
• NCBI ID: WP_198463803.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain FDAARGOS_1045
• Function: repress natural transformation (predicted from homology) Competence regulation

Genomic Context

Location: 733018..743926

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6I02_RS03210 (I6I02_03210)	-	733549..734541 (+)	993	WP_198463801.1	ATP-binding cassette domain-containing protein	-
I6I02_RS03215 (I6I02_03215)	-	734543..735361 (+)	819	WP_049546120.1	ABC transporter permease	-
I6I02_RS03220 (I6I02_03220)	-	735363..736148 (+)	786	WP_195435314.1	ABC transporter permease	-
I6I02_RS03225 (I6I02_03225)	-	736187..736648 (+)	462	WP_198463968.1	GNAT family N-acetyltransferase	-
I6I02_RS03230 (I6I02_03230)	-	737019..737912 (+)	894	WP_198463802.1	hypothetical protein	-
I6I02_RS03235 (I6I02_03235)	comR/comR1	738018..738926 (-)	909	WP_198463803.1	helix-turn-helix domain-containing protein	Regulator
I6I02_RS03240 (I6I02_03240)	-	739084..739803 (-)	720	WP_198463804.1	ABC transporter permease	-
I6I02_RS03245 (I6I02_03245)	-	739796..740632 (-)	837	WP_198463805.1	ABC transporter ATP-binding protein	-
I6I02_RS03250 (I6I02_03250)	comR	740718..741626 (-)	909	WP_198463806.1	helix-turn-helix domain-containing protein	Regulator
I6I02_RS03255 (I6I02_03255)	-	741843..742364 (+)	522	WP_226973104.1	RDD family protein	-
I6I02_RS03260 (I6I02_03260)	-	742488..743408 (+)	921	WP_107373180.1	multidrug resistance efflux transporter family protein	-

Sequence

Protein

• Length: 302 a.a.
• Molecular weight: 35698.09 Da
• Isoelectric Point: 4.4910

>NTDB_id=453756 I6I02_RS03235 WP_198463803.1 738018..738926(-) (comR/comR1) [Streptococcus salivarius strain FDAARGOS_1045]
MSEDIKIEIGKRIREERERLGLTREQVCDTEEELTVKQLMRIELGRSLPTIVKLQYISDKLGVSLNYLLGETKLDIPEDY
YQAKYKLMKSPVYGDLERIKKKLQDIEDLYDNYIDILPEDELFAIDIIERTLNFMVMEEDSLIESVFEDYLTQALKKEAY
SLNDLLLISYYALRCQDYDYDKGIIDKFRRKLIKQELQGEELFNIELMGALTSIAGIYVMHHDYKDMKSVVDKLYEIMHS
CMQHSYQPGIIVFEAKYYLFYENNRDKATELYNTATVLAEAFGDEVFIKNLKMEMEKDLNIK

Nucleotide

• Length: 909 bp

>NTDB_id=453756 I6I02_RS03235 WP_198463803.1 738018..738926(-) (comR/comR1) [Streptococcus salivarius strain FDAARGOS_1045]
ATGTCTGAAGATATTAAAATCGAGATTGGAAAAAGAATCCGTGAAGAACGTGAACGACTTGGTTTAACACGTGAGCAGGT
TTGTGATACCGAAGAAGAATTAACTGTCAAACAGCTGATGAGAATTGAACTCGGACGTTCTTTACCAACCATTGTCAAAC
TGCAGTATATCAGTGATAAATTAGGAGTTTCCCTCAACTATTTGTTAGGTGAAACAAAACTAGACATTCCTGAAGATTAT
TATCAGGCTAAATATAAACTCATGAAGTCTCCTGTCTATGGCGACCTCGAACGTATCAAGAAAAAGCTGCAGGACATTGA
AGACCTCTACGACAACTATATTGATATTCTACCAGAAGACGAGCTTTTTGCTATTGATATCATTGAAAGAACGTTAAATT
TTATGGTTATGGAAGAAGATAGTCTTATTGAATCTGTATTTGAAGACTATTTGACTCAAGCTTTGAAAAAAGAAGCATAT
TCCTTAAATGACCTTCTATTAATTTCATACTATGCATTACGATGTCAGGATTATGACTATGATAAAGGAATAATTGACAA
ATTTAGACGTAAATTAATTAAGCAAGAATTACAAGGTGAAGAGCTGTTTAATATTGAATTAATGGGAGCTCTAACATCTA
TAGCTGGTATTTACGTCATGCATCATGACTATAAAGACATGAAATCTGTTGTAGATAAATTGTATGAGATTATGCATTCA
TGTATGCAACATTCCTATCAACCAGGTATCATAGTTTTTGAAGCGAAATATTATCTTTTCTATGAGAACAATAGAGATAA
AGCGACTGAGCTTTATAATACGGCTACCGTACTAGCTGAAGCTTTCGGTGATGAAGTATTCATAAAAAACCTAAAAATGG
AAATGGAAAAAGATTTAAACATAAAATAG

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (77-295)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	38.983	97.682	0.381
comR	Streptococcus thermophilus LMD-9	38.621	96.026	0.371
comR	Streptococcus thermophilus LMG 18311	38.621	96.026	0.371
comR	Streptococcus salivarius strain HSISS4	38.621	96.026	0.371
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	37.801	96.358	0.364
comR	Streptococcus salivarius SK126	38.38	94.04	0.361