Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE1   Type   Regulator
Locus tag   I6I02_RS01835 Genome accession   NZ_CP066093
Coordinates   371723..372460 (+) Length   245 a.a.
NCBI ID   WP_002891534.1    Uniprot ID   J7T4Q1
Organism   Streptococcus salivarius strain FDAARGOS_1045     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 366723..377460
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I02_RS01820 (I6I02_01820) - 367695..368447 (+) 753 WP_070437755.1 DUF4767 domain-containing protein -
  I6I02_RS01825 (I6I02_01825) tehB 368530..369408 (-) 879 WP_037598358.1 SAM-dependent methyltransferase TehB -
  I6I02_RS01830 (I6I02_01830) - 370187..371509 (-) 1323 WP_198463690.1 matrixin family metalloprotease -
  I6I02_RS01835 (I6I02_01835) comE/comE1 371723..372460 (+) 738 WP_002891534.1 LytR/AlgR family response regulator transcription factor Regulator
  I6I02_RS01840 (I6I02_01840) - 372772..373950 (+) 1179 WP_037598353.1 sensor histidine kinase -
  I6I02_RS01845 (I6I02_01845) - 374062..375441 (+) 1380 WP_037598350.1 hypothetical protein -
  I6I02_RS01850 (I6I02_01850) rpsP 375606..375878 (+) 273 WP_002884675.1 30S ribosomal protein S16 -
  I6I02_RS01855 (I6I02_01855) - 375890..376138 (+) 249 WP_002884680.1 KH domain-containing protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28060.04 Da        Isoelectric Point: 4.7802

>NTDB_id=453741 I6I02_RS01835 WP_002891534.1 371723..372460(+) (comE/comE1) [Streptococcus salivarius strain FDAARGOS_1045]
MLSIIVLEDDALQRHRVGRLLDEAVEESKAVVDGITFYEQGQELLDADRGSGKSMVYLLDIDLKNQTKQGLDIGLEIRKE
DLKAQIAFVTAYSEFMPLTFRYKIQALDFVDKSMEDVDLKRALVELLDFAYSQVEQETKAQSLTVKTDKNDVNIPYDDIL
YIETAPVPHKLIAHTKSNLVEFYGKIAEVAKLDDIFFQTHRSFVVNVNNVTSVDRTANMVFFEGNESCLLSRTRKKELLE
RLKNR

Nucleotide


Download         Length: 738 bp        

>NTDB_id=453741 I6I02_RS01835 WP_002891534.1 371723..372460(+) (comE/comE1) [Streptococcus salivarius strain FDAARGOS_1045]
ATGCTTTCTATTATCGTCCTTGAAGATGATGCCTTGCAGCGTCATCGTGTTGGTCGTTTATTGGACGAAGCAGTTGAGGA
GTCGAAGGCCGTTGTTGATGGGATTACTTTTTATGAACAGGGTCAGGAATTGTTAGATGCTGATAGAGGTTCGGGTAAAT
CCATGGTTTATCTTTTGGATATTGACCTTAAAAATCAAACTAAGCAGGGACTAGATATTGGGCTTGAAATCCGTAAGGAA
GACTTGAAAGCACAAATTGCCTTTGTTACAGCTTACTCGGAGTTTATGCCCTTGACCTTCCGTTATAAGATTCAAGCTCT
AGATTTTGTCGATAAATCCATGGAAGATGTGGATCTTAAGAGAGCTTTAGTAGAACTTTTAGATTTTGCTTATTCACAGG
TTGAGCAAGAAACCAAGGCACAGAGTCTAACTGTTAAAACGGATAAAAATGATGTTAATATTCCTTATGATGATATTTTA
TACATTGAGACAGCCCCTGTGCCACATAAGTTAATCGCTCATACCAAGTCAAACCTAGTGGAATTCTATGGGAAAATTGC
AGAAGTAGCAAAATTGGATGATATTTTCTTCCAAACGCACCGCTCTTTTGTTGTCAATGTGAATAATGTGACAAGTGTGG
ATCGTACAGCTAATATGGTCTTCTTTGAGGGAAACGAGTCATGCCTCCTATCGCGGACACGTAAAAAGGAACTTTTGGAA
CGTTTGAAAAATCGTTAG

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(152-242)

Response regulator receiver domain (Response_reg)

(4-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7T4Q1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE1 Streptococcus equinus JB1

37.449

99.184

0.371