Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   FOC72_RS02860 Genome accession   NZ_CP054570
Coordinates   576314..577015 (+) Length   233 a.a.
NCBI ID   WP_002894937.1    Uniprot ID   A0A0B7GM19
Organism   Streptococcus sanguinis strain FDAARGOS_770     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 571314..582015
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC72_RS02835 (FOC72_02835) - 572516..572914 (-) 399 WP_002894925.1 hypothetical protein -
  FOC72_RS02840 (FOC72_02840) - 573023..573682 (-) 660 WP_002894927.1 amino acid ABC transporter permease -
  FOC72_RS02845 (FOC72_02845) - 573693..574373 (-) 681 WP_002894931.1 amino acid ABC transporter permease -
  FOC72_RS02850 (FOC72_02850) - 574386..575198 (-) 813 WP_002894933.1 transporter substrate-binding domain-containing protein -
  FOC72_RS02855 (FOC72_02855) - 575213..575974 (-) 762 WP_002894934.1 amino acid ABC transporter ATP-binding protein -
  FOC72_RS02860 (FOC72_02860) micA 576314..577015 (+) 702 WP_002894937.1 response regulator YycF Regulator
  FOC72_RS02865 (FOC72_02865) micB 577008..578354 (+) 1347 WP_002894938.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FOC72_RS02870 (FOC72_02870) vicX 578364..579164 (+) 801 WP_002894939.1 MBL fold metallo-hydrolase Regulator
  FOC72_RS02875 (FOC72_02875) - 579256..579615 (+) 360 WP_002894940.1 DUF454 family protein -
  FOC72_RS02880 (FOC72_02880) rnc 579737..580435 (+) 699 WP_002894942.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26735.63 Da        Isoelectric Point: 4.7458

>NTDB_id=453490 FOC72_RS02860 WP_002894937.1 576314..577015(+) (micA) [Streptococcus sanguinis strain FDAARGOS_770]
MKKILVVDDEKPISDIIKFNMAKEGYEVLTAFDGKEALEMFEAEQPDILILDLMLPEVDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRADLVVENQVEESGPNELTIGELQILPDAFVAKKHGKELELTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=453490 FOC72_RS02860 WP_002894937.1 576314..577015(+) (micA) [Streptococcus sanguinis strain FDAARGOS_770]
ATGAAGAAAATATTAGTTGTAGATGATGAGAAGCCAATCTCAGATATTATTAAGTTTAATATGGCCAAAGAAGGCTATGA
GGTTTTGACTGCCTTTGATGGCAAGGAAGCCTTGGAAATGTTTGAAGCAGAACAGCCAGACATCTTGATTCTGGACTTGA
TGCTGCCGGAAGTGGACGGACTGGAAGTTGCTCGGACTATTCGCAAGACCAGCAATGTTCCGATTATTGTATTGTCTGCT
AAGGACAGTGAGTTTGACAAGGTTATCGGCCTTGAAATCGGTGCAGATGACTATGTGACCAAGCCTTTCTCAAATCGTGA
GCTGCAGGCGCGTGTCAAGGCACTTCTTCGTCGGGCAGACCTTGTTGTGGAAAACCAAGTAGAAGAAAGTGGCCCGAACG
AGTTGACCATTGGAGAACTGCAGATTTTGCCAGATGCTTTTGTTGCTAAGAAGCATGGCAAGGAGCTGGAGCTGACCCAC
CGTGAGTTTGAACTGCTTCACCATTTGGCGACACATATCGGTCAGGTCATGACACGTGAGCACTTGCTGGAAACAGTATG
GGGCTATGACTATTTTGGCGATGTCCGTACAGTGGATGTGACGATTCGCCGTCTGCGTGAAAAGATTGAAGATACGCCAA
GCCGTCCTGAGTATATCTTGACTCGCCGCGGAGTTGGCTATTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7GM19

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.833

100

0.828
  vicR Streptococcus mutans UA159

80.426

100

0.811
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.231

98.283

0.425
  covR Streptococcus salivarius strain HSISS4

42.174

98.712

0.416
  scnR Streptococcus mutans UA159

36.957

98.712

0.365