Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   FOC72_RS02865 Genome accession   NZ_CP054570
Coordinates   577008..578354 (+) Length   448 a.a.
NCBI ID   WP_002894938.1    Uniprot ID   A0A3R9HU52
Organism   Streptococcus sanguinis strain FDAARGOS_770     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 572008..583354
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC72_RS02835 (FOC72_02835) - 572516..572914 (-) 399 WP_002894925.1 hypothetical protein -
  FOC72_RS02840 (FOC72_02840) - 573023..573682 (-) 660 WP_002894927.1 amino acid ABC transporter permease -
  FOC72_RS02845 (FOC72_02845) - 573693..574373 (-) 681 WP_002894931.1 amino acid ABC transporter permease -
  FOC72_RS02850 (FOC72_02850) - 574386..575198 (-) 813 WP_002894933.1 transporter substrate-binding domain-containing protein -
  FOC72_RS02855 (FOC72_02855) - 575213..575974 (-) 762 WP_002894934.1 amino acid ABC transporter ATP-binding protein -
  FOC72_RS02860 (FOC72_02860) micA 576314..577015 (+) 702 WP_002894937.1 response regulator YycF Regulator
  FOC72_RS02865 (FOC72_02865) micB 577008..578354 (+) 1347 WP_002894938.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FOC72_RS02870 (FOC72_02870) vicX 578364..579164 (+) 801 WP_002894939.1 MBL fold metallo-hydrolase Regulator
  FOC72_RS02875 (FOC72_02875) - 579256..579615 (+) 360 WP_002894940.1 DUF454 family protein -
  FOC72_RS02880 (FOC72_02880) rnc 579737..580435 (+) 699 WP_002894942.1 ribonuclease III -

Sequence

Protein


Download         Length: 448 a.a.        Molecular weight: 50860.77 Da        Isoelectric Point: 4.4112

>NTDB_id=453491 FOC72_RS02865 WP_002894938.1 577008..578354(+) (micB) [Streptococcus sanguinis strain FDAARGOS_770]
MIEAIKQFVISADFVFAIIIIGFIVVVALLLLENRRDNQKLVQLNQKVKDLIAGDYSEVLDMQGSPEITDMTNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIITINDMATKQLGVKRDEVQNMSILDLLSISDEYDLRDLITNVPE
LTIDSQDENGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQDKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFVKVSLNETNRMMRMVTDLLSLSRIDNETSHLEVELTNFTAFITFILNRFDKIKNQDETKKYEIIRDYPITPIW
VEIDTDKLTQVIDNIMNNAIKYSPDGGTITVSIKTTDEQLILSIADEGLGIPKQDLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIIKQHQGFIWAKSEYGVGSTFTIVLPYENDGVRDDDWDNEDI

Nucleotide


Download         Length: 1347 bp        

>NTDB_id=453491 FOC72_RS02865 WP_002894938.1 577008..578354(+) (micB) [Streptococcus sanguinis strain FDAARGOS_770]
ATGATTGAAGCAATTAAACAATTTGTGATTTCTGCGGATTTTGTCTTTGCAATCATTATTATCGGCTTCATTGTAGTTGT
GGCCTTGCTTTTATTGGAAAATCGCCGGGATAACCAAAAGCTTGTACAGCTTAATCAAAAGGTTAAAGATTTGATTGCAG
GTGACTATTCTGAAGTGCTGGACATGCAGGGAAGTCCGGAAATCACAGATATGACCAACAGTATCAATGATCTTTCAGAG
GTCATTCGACTGACACATGAAAACCTTGAGCAAGAAACAAAACGCCTTTCCAGTATCCTGTCCTATATGACAGATGGCGT
GCTTGCGACCAACCGCCGGGGACAGATTATTACTATCAACGATATGGCAACCAAGCAGTTGGGAGTTAAGAGAGATGAGG
TCCAAAATATGAGTATTTTGGATCTGCTTTCGATTTCAGACGAGTATGATTTGCGGGATCTAATTACCAATGTTCCTGAG
CTGACGATAGATTCTCAGGATGAAAATGGTGAGTACTTGAGCTTGCGGGTTCGCTTTGCCTTGGTAAGGCGGGAGTCGGG
CTTCATTTCTGGTTTGGTAGCTGTCCTGCATGATACGACCGAGCAGGACAAGGAAGAGCGGGAGCGTCGCCTCTTTGTCT
CTAACGTCAGCCATGAGTTGCGGACTCCGCTGACCAGTGTCAAGTCCTATCTGGAAGCCTTGGATGAGGGAGCCTTGTCT
GAGCCAGTAGCACCGGACTTTGTCAAGGTATCGCTCAATGAAACCAATCGCATGATGCGGATGGTGACGGACTTGCTTAG
TCTATCCCGTATCGACAATGAGACCAGTCATCTGGAAGTGGAACTGACGAATTTCACAGCCTTTATCACTTTTATCCTCA
ATCGCTTTGACAAGATAAAAAATCAAGACGAGACCAAGAAATATGAGATTATCCGTGATTATCCTATAACACCGATCTGG
GTGGAGATTGATACAGATAAGCTGACCCAGGTGATTGATAATATCATGAACAATGCCATCAAGTATTCGCCAGATGGTGG
AACCATTACTGTTTCCATCAAGACAACTGATGAGCAGTTGATCCTCTCGATTGCGGATGAAGGTCTGGGAATTCCCAAGC
AGGACCTGCCTAAGATTTTTGACCGCTTTTATCGAGTGGACAAGGCACGCAGTCGCGCACAGGGCGGAACAGGTCTGGGG
CTGGCTATTGCCAAGGAAATTATCAAGCAGCATCAGGGCTTTATCTGGGCTAAGAGTGAGTATGGTGTGGGCTCGACCTT
TACCATTGTCTTGCCTTATGAGAATGATGGTGTCCGGGATGACGACTGGGATAATGAAGATATATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-198)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3R9HU52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

78.588

97.991

0.77
  vicK Streptococcus mutans UA159

70.72

89.955

0.636