NTDB

Overview

Name	clpP	Type	Regulator
Locus tag	FOC72_RS02140	Genome accession	NZ_CP054570
Coordinates	434028..434618 (+)	Length	196 a.a.
NCBI ID	WP_002894674.1	Uniprot ID	A0A2X3VD36
Organism	Streptococcus sanguinis strain FDAARGOS_770
Function	degradation of ComX; degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 429028..439618

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOC72_RS02125 (FOC72_02125)	-	429763..430374 (+)	612	WP_032913640.1	glutathione S-transferase family protein	-
FOC72_RS02130 (FOC72_02130)	mgtA	430532..433192 (+)	2661	WP_002894669.1	magnesium-translocating P-type ATPase	-
FOC72_RS02135 (FOC72_02135)	upp	433290..433919 (+)	630	WP_002894672.1	uracil phosphoribosyltransferase	-
FOC72_RS02140 (FOC72_02140)	clpP	434028..434618 (+)	591	WP_002894674.1	ATP-dependent Clp protease proteolytic subunit	Regulator
FOC72_RS02145 (FOC72_02145)	-	434780..435049 (+)	270	WP_002894676.1	YlbG family protein	-
FOC72_RS02150 (FOC72_02150)	-	435138..436298 (+)	1161	WP_002894677.1	ABC transporter substrate-binding protein	-
FOC72_RS02155 (FOC72_02155)	-	436544..437413 (+)	870	WP_002894678.1	branched-chain amino acid ABC transporter permease	-
FOC72_RS02160 (FOC72_02160)	-	437417..438370 (+)	954	WP_002894679.1	branched-chain amino acid ABC transporter permease	-
FOC72_RS02165 (FOC72_02165)	-	438370..439134 (+)	765	WP_002894680.1	ABC transporter ATP-binding protein	-

Sequence

Protein

Download Length: 196 a.a. Molecular weight: 21567.55 Da Isoelectric Point: 4.5179

                                >NTDB_id=453488 FOC72_RS02140 WP_002894674.1 434028..434618(+) (clpP) [Streptococcus sanguinis strain FDAARGOS_770]

MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN

FIKSDVQTIVMGVAASMGTIIASSGAKGKRFMLPNAEYLIHQPMGGAGSGTQQTDMAIVAEHLLRTRNTLEKILAENSGK

SVEQIHKDAERDYWMSAQETLEYGFIDEIMENSNLN

Nucleotide

Download Length: 591 bp

                                >NTDB_id=453488 FOC72_RS02140 WP_002894674.1 434028..434618(+) (clpP) [Streptococcus sanguinis strain FDAARGOS_770]

ATGATTCCTGTAGTTATTGAACAAACCAGCCGAGGAGAACGCTCCTATGATATTTACTCCCGGCTATTAAAAGACCGCAT

TATCATGCTGACTGGCCCAGTAGAGGATAATATGGCTAATTCAGTCATTGCCCAGCTCCTTTTCTTGGATGCACAGGACA

ATACTAAAGATATTTATCTCTATGTAAATACGCCGGGGGGATCCGTTTCAGCAGGTCTGGCTATTGTGGATACTATGAAC

TTCATCAAGTCTGATGTTCAGACCATTGTTATGGGTGTAGCTGCCAGCATGGGAACAATCATTGCTTCCAGTGGTGCTAA

GGGCAAACGCTTCATGCTTCCAAATGCAGAATATCTGATTCACCAGCCGATGGGCGGAGCTGGAAGCGGCACTCAGCAAA

CGGATATGGCCATTGTAGCTGAACACTTGCTTAGAACTCGTAATACCTTGGAAAAAATCTTAGCTGAAAACTCTGGCAAG

TCCGTTGAGCAAATCCACAAAGATGCAGAACGCGATTACTGGATGAGCGCTCAAGAAACCTTGGAATACGGCTTTATTGA

CGAAATCATGGAAAATAGCAACTTGAACTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A2X3VD36

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
clpP	Streptococcus pneumoniae Rx1	90.816	100	0.908
clpP	Streptococcus pneumoniae D39	90.816	100	0.908
clpP	Streptococcus pneumoniae R6	90.816	100	0.908
clpP	Streptococcus pneumoniae TIGR4	90.816	100	0.908
clpP	Streptococcus pyogenes MGAS315	89.744	99.49	0.893
clpP	Streptococcus pyogenes JRS4	89.744	99.49	0.893
clpP	Streptococcus thermophilus LMG 18311	88.718	99.49	0.883
clpP	Streptococcus mutans UA159	88.718	99.49	0.883
clpP	Streptococcus thermophilus LMD-9	88.718	99.49	0.883
clpP	Lactococcus lactis subsp. cremoris KW2	87.692	99.49	0.872
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	87.179	99.49	0.867
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	59.585	98.469	0.587
clpP	Bacillus subtilis subsp. subtilis str. 168	56.477	98.469	0.556

Detailed information NTG0453488