Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   HRE60_RS07390 Genome accession   NZ_CP054153
Coordinates   1665806..1666501 (-) Length   231 a.a.
NCBI ID   WP_181670615.1    Uniprot ID   A0A7L6WL61
Organism   Streptococcus salivarius strain DB-B5     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1660806..1671501
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HRE60_RS07375 (HRE60_07375) - 1661617..1662162 (-) 546 WP_181670612.1 GNAT family N-acetyltransferase -
  HRE60_RS07380 (HRE60_07380) - 1662228..1663490 (-) 1263 WP_181670613.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  HRE60_RS07385 (HRE60_07385) comEC/celB 1663576..1665816 (-) 2241 WP_181670614.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  HRE60_RS07390 (HRE60_07390) comEA 1665806..1666501 (-) 696 WP_181670615.1 helix-hairpin-helix domain-containing protein Machinery gene
  HRE60_RS07395 (HRE60_07395) - 1666611..1667366 (-) 756 WP_181670616.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  HRE60_RS07400 (HRE60_07400) - 1667496..1668431 (+) 936 WP_181670617.1 polysaccharide deacetylase family protein -
  HRE60_RS07405 (HRE60_07405) - 1668481..1669245 (+) 765 WP_037599202.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  HRE60_RS07410 (HRE60_07410) - 1669249..1669518 (+) 270 WP_181670618.1 GIY-YIG nuclease family protein -
  HRE60_RS07415 (HRE60_07415) - 1669533..1670897 (-) 1365 WP_181670619.1 hypothetical protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24405.29 Da        Isoelectric Point: 4.7259

>NTDB_id=451182 HRE60_RS07390 WP_181670615.1 1665806..1666501(-) (comEA) [Streptococcus salivarius strain DB-B5]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGNSMEAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSEKDK
SKVTVDVKGAVANPGVYTLKASARVTDAIKAAGGMTEDADAKSINLAASLSDEEVVYVATKDENLSVLGQSGTGQVSDKG
GQTNTKDGKINLNTATSEELQTISGIGAKRAEDIIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=451182 HRE60_RS07390 WP_181670615.1 1665806..1666501(-) (comEA) [Streptococcus salivarius strain DB-B5]
GTGAAGGAAAAGATTTTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTGCTGATGGTGATTTTTTG
CTTCTTTCTATGGATGACTTGTGGTGCTGGCAACAGCATGGAGGCGGAGACATCTTATACAGATGTGACAGCTTTGTCAA
CCTCCTCATCCAAACAAAGCTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACTGAAGGAAGTGAAAAGGATAAG
TCAAAAGTAACAGTAGATGTTAAGGGGGCTGTGGCTAATCCGGGTGTTTATACCTTAAAAGCAAGCGCTAGGGTGACTGA
TGCCATCAAAGCTGCTGGGGGAATGACTGAGGATGCGGATGCTAAGAGTATTAATTTAGCTGCAAGCCTGTCGGACGAAG
AGGTTGTCTATGTGGCAACTAAGGATGAAAACCTCTCTGTCCTTGGTCAATCAGGAACTGGTCAGGTCTCTGACAAAGGA
GGGCAAACTAATACTAAGGATGGGAAAATTAACTTAAATACAGCGACCTCAGAGGAGTTGCAAACCATTTCTGGAATTGG
AGCTAAGCGGGCAGAGGATATCATTGCCTATCGTGAGAGTCATGGCGGCTTTCAGTCTGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACTTTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(168-228)

SLBB domain (SLBB)

(85-138)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7L6WL61

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

92.641

100

0.926
  comEA/celA/cilE Streptococcus mitis SK321

41.048

99.134

0.407
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

39.912

98.701

0.394
  comEA/celA/cilE Streptococcus mitis NCTC 12261

39.474

98.701

0.39
  comEA/celA/cilE Streptococcus pneumoniae Rx1

39.474

98.701

0.39
  comEA/celA/cilE Streptococcus pneumoniae D39

39.474

98.701

0.39
  comEA/celA/cilE Streptococcus pneumoniae R6

39.474

98.701

0.39