Detailed information NTG0451181

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: HRE60_RS07385
• Genome accession: NZ_CP054153
• Coordinates: 1663576..1665816 (-)
• Length: 746 a.a.
• NCBI ID: WP_181670614.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain DB-B5
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1658576..1670816

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HRE60_RS07365 (HRE60_07365)	-	1659439..1660299 (-)	861	WP_004183173.1	methionyl aminopeptidase	-
HRE60_RS07370 (HRE60_07370)	spxR	1660344..1661624 (-)	1281	WP_002884454.1	CBS-HotDog domain-containing transcription factor SpxR	-
HRE60_RS07375 (HRE60_07375)	-	1661617..1662162 (-)	546	WP_181670612.1	GNAT family N-acetyltransferase	-
HRE60_RS07380 (HRE60_07380)	-	1662228..1663490 (-)	1263	WP_181670613.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
HRE60_RS07385 (HRE60_07385)	comEC/celB	1663576..1665816 (-)	2241	WP_181670614.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
HRE60_RS07390 (HRE60_07390)	comEA	1665806..1666501 (-)	696	WP_181670615.1	helix-hairpin-helix domain-containing protein	Machinery gene
HRE60_RS07395 (HRE60_07395)	-	1666611..1667366 (-)	756	WP_181670616.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
HRE60_RS07400 (HRE60_07400)	-	1667496..1668431 (+)	936	WP_181670617.1	polysaccharide deacetylase family protein	-
HRE60_RS07405 (HRE60_07405)	-	1668481..1669245 (+)	765	WP_037599202.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
HRE60_RS07410 (HRE60_07410)	-	1669249..1669518 (+)	270	WP_181670618.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84403.16 Da
• Isoelectric Point: 9.8751

>NTDB_id=451181 HRE60_RS07385 WP_181670614.1 1663576..1665816(-) (comEC/celB) [Streptococcus salivarius strain DB-B5]
MWLKKAPINLFSLALLIAALYFTIFATNVYAIGALSFLLGCFLKHHWKNKAALKLVGLVGSFFLIYFLFLHHRASIQDKQ
APTAINQVTLVADTLSVNGEQLSAIGKAKGQTYQVFYRLKSEKEQYFFKTTSQTLVLKGKIKLSPVTGQRNFQGFNYQSY
LASQGIYRMAQIERLDHVVSQKNTSPLAFFHQLRRRALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTGLGIIHL
FALSGMQVGFFLGWFRYGLLRFGLPKDYLFIILLPFSLCYGLMTGWTASVLRSLLQSLLAEFGIKKLDNMGITLLLLFLF
LPHFLLTVGGVLSCSYAFLLCLFNFEEMSSLKKSICTSLVLSLGILPFLTYYYGTFQPVSLILTAMFSIVFDSFLLPVLT
VFFALSGLVIFSQINPLFEWMETLLTWIRSWIGQPLILGKPSLFQFGLMIAVLIMFFDFWKKPQFRICLLMIFGLLMVWV
KHPLTNEVTMVDVGQGDSIFLRSMKGDTILIDVGGKVTFGSKEKWQEGSQTSNAEKTLIPYLQARGVSQIDHLVLTHTDT
DHIGDLEEVAKRFKIKEICVSQGALTKPSFVKRLRTLKCPVRTLKAGDNLPMMGSKLQVLYPNKVGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMVSYPNLKASVLKAGHHGSKGSSSEAFLDQLQPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDQNGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=451181 HRE60_RS07385 WP_181670614.1 1663576..1665816(-) (comEC/celB) [Streptococcus salivarius strain DB-B5]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCTTGGCTTTGTTAATAGCTGCTCTTTATTTTACGATTTTTGCCAC
TAATGTTTATGCTATTGGGGCGTTGTCTTTTCTTTTAGGATGTTTTTTGAAGCATCATTGGAAGAATAAGGCAGCCCTAA
AGTTGGTGGGGCTTGTAGGTAGTTTCTTTTTGATTTACTTTTTATTCTTGCACCACAGAGCTAGCATACAAGATAAACAA
GCTCCTACTGCAATCAATCAAGTGACTCTGGTTGCTGATACGCTATCGGTTAATGGTGAGCAATTATCAGCTATTGGAAA
GGCAAAGGGACAAACCTATCAGGTTTTTTACCGACTCAAATCTGAGAAGGAGCAGTATTTTTTTAAGACTACTAGTCAAA
CCTTGGTATTAAAAGGGAAAATAAAGTTATCCCCAGTAACTGGTCAACGTAATTTTCAAGGGTTTAATTATCAGTCTTAT
CTAGCCAGTCAAGGCATTTATCGAATGGCTCAGATTGAGCGCTTGGATCATGTGGTGTCTCAAAAAAACACATCTCCCCT
AGCTTTTTTCCATCAACTGAGGAGGAGGGCTTTGGTTCATATTCAGACGCATTTTCCTAATCCTATGAGACACTATATGA
CAGGTCTGCTCTTTGGGTATTTGGATAAGGAGTTTGATGAGCAAAGTCAGCTTTACACAGGCTTAGGTATTATTCATCTA
TTCGCACTTTCGGGGATGCAAGTGGGCTTTTTTCTGGGATGGTTTCGCTACGGACTCCTACGCTTTGGCCTTCCTAAAGA
TTATCTATTTATTATTTTGCTGCCTTTTTCCTTATGCTATGGCTTAATGACAGGTTGGACAGCTTCAGTCCTACGTTCCC
TGCTTCAAAGTTTGTTGGCTGAGTTTGGTATTAAAAAACTAGACAATATGGGAATAACCTTGCTTCTATTGTTTCTCTTT
TTACCTCATTTTCTTTTGACAGTGGGAGGTGTTTTAAGTTGTTCCTATGCCTTTTTGTTGTGTTTGTTTAATTTTGAGGA
GATGTCATCTCTTAAAAAGTCAATCTGTACGAGTTTGGTATTGAGTCTTGGGATTTTGCCTTTTCTAACTTACTATTATG
GGACCTTTCAACCGGTGAGTTTAATTCTGACGGCGATGTTTTCGATAGTATTTGATAGCTTTCTCTTACCTGTCTTGACG
GTCTTCTTTGCCCTTTCAGGGCTGGTAATCTTTTCTCAAATTAACCCACTTTTTGAATGGATGGAGACTCTTTTAACTTG
GATACGATCCTGGATAGGCCAGCCTTTGATTCTAGGGAAACCTAGTTTGTTTCAGTTTGGCTTGATGATAGCTGTATTGA
TTATGTTCTTTGATTTTTGGAAAAAGCCCCAGTTTAGGATTTGCCTTTTGATGATTTTTGGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTATGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
TACCATCCTCATTGATGTGGGTGGCAAGGTGACTTTCGGCTCAAAGGAAAAATGGCAGGAGGGGAGCCAGACGAGCAATG
CGGAGAAAACCTTGATTCCCTATCTACAGGCTAGGGGAGTGTCTCAAATTGACCATCTGGTCCTGACTCATACGGATACA
GACCATATTGGTGATTTGGAAGAAGTAGCCAAGCGGTTTAAGATTAAGGAAATCTGTGTCAGTCAAGGAGCTTTGACTAA
GCCTAGTTTTGTGAAACGACTTCGAACTTTAAAATGCCCAGTTCGCACTCTAAAGGCTGGAGACAACTTACCCATGATGG
GAAGTAAGCTACAGGTTCTTTATCCAAATAAAGTTGGTGATGGTGGTAACAACGATTCGATAGTTCTTTACGGAAAACTA
TTAGGAAGTAGTTTTTTGTTTACGGGTGATCTGGAAAAAGAAGGAGAGGAGGAACTGATGGTCAGCTATCCTAATTTAAA
GGCTAGTGTCCTCAAAGCCGGACACCACGGTTCAAAAGGGTCATCGTCTGAAGCGTTTTTGGACCAGTTGCAGCCCTCCC
TTGCCCTTGTTTCAGCTGGTGAGAATAATCGTTATAAACATCCAAATGATGAAACTTTGGAGCGTTTCAAGGAACGTCAC
ATTAAGGTTTTACGAACAGACCAGAACGGTGCTATCCGTTTTAAGGGGTGGTTTAAGTGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-462)

• Domain of unknown function (DUF4131) (DUF4131) (29-169)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.193	100	0.483
comEC/celB	Streptococcus mitis SK321	47.861	100	0.48
comEC/celB	Streptococcus pneumoniae R6	46.791	100	0.469
comEC/celB	Streptococcus pneumoniae D39	46.791	100	0.469
comEC/celB	Streptococcus pneumoniae Rx1	46.791	100	0.469
comEC/celB	Streptococcus pneumoniae TIGR4	46.452	100	0.465
comEC	Lactococcus lactis subsp. cremoris KW2	43.649	99.196	0.433