Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   HRE60_RS04345 Genome accession   NZ_CP054153
Coordinates   891221..891928 (+) Length   235 a.a.
NCBI ID   WP_002884978.1    Uniprot ID   A0AB33ZBK5
Organism   Streptococcus salivarius strain DB-B5     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 886221..896928
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HRE60_RS04320 (HRE60_04320) - 886991..887758 (-) 768 WP_104020925.1 amino acid ABC transporter ATP-binding protein -
  HRE60_RS04325 (HRE60_04325) - 887947..888597 (-) 651 WP_181671215.1 amino acid ABC transporter permease -
  HRE60_RS04330 (HRE60_04330) - 888609..889307 (-) 699 WP_002886251.1 amino acid ABC transporter permease -
  HRE60_RS04335 (HRE60_04335) - 889325..890158 (-) 834 WP_181671216.1 transporter substrate-binding domain-containing protein -
  HRE60_RS04340 (HRE60_04340) - 890168..890935 (-) 768 WP_181671217.1 amino acid ABC transporter ATP-binding protein -
  HRE60_RS04345 (HRE60_04345) vicR 891221..891928 (+) 708 WP_002884978.1 response regulator YycF Regulator
  HRE60_RS04350 (HRE60_04350) vicK 891921..893264 (+) 1344 WP_118189480.1 cell wall metabolism sensor histidine kinase VicK Regulator
  HRE60_RS04355 (HRE60_04355) vicX 893267..894079 (+) 813 WP_048675076.1 MBL fold metallo-hydrolase Regulator
  HRE60_RS04360 (HRE60_04360) - 894138..894497 (+) 360 WP_002885010.1 YbaN family protein -
  HRE60_RS04365 (HRE60_04365) - 894549..895763 (-) 1215 WP_181671218.1 aminoacyltransferase -
  HRE60_RS04370 (HRE60_04370) yidA 895765..896574 (-) 810 WP_181671219.1 sugar-phosphatase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27045.90 Da        Isoelectric Point: 4.8387

>NTDB_id=451165 HRE60_RS04345 WP_002884978.1 891221..891928(+) (vicR) [Streptococcus salivarius strain DB-B5]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=451165 HRE60_RS04345 WP_002884978.1 891221..891928(+) (vicR) [Streptococcus salivarius strain DB-B5]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCGATTTCGGATATCATCAAGTTTAATCTAACTAAAGAAGGTTATGA
AGTGGTTACAGCCTTTGATGGTCGTGAAGCTTTGGAGCAGTTTGAAGCTGAAAAGCCAGACTTGGTCATCCTGGACTTGA
TGTTGCCTGAACTAGATGGTTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCACACACCGATTATCATGCTTTCCGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGGCTAGAAATTGGGGCGGACGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCTGGTA
AGCAGGAGATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCGTTTGTTGCTAAAAAACGTGGAAATGAAGTCGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATCTGGCAACTCACATGGGACAAGTGATGACGCGTGAGCATTTACTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.532

100

0.855
  micA Streptococcus pneumoniae Cp1015

80.687

99.149

0.8
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

38.559

100

0.387