Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FOC63_RS10015 Genome accession   NZ_CP054015
Coordinates   2002983..2003657 (-) Length   224 a.a.
NCBI ID   WP_009854247.1    Uniprot ID   A0A139MP14
Organism   Streptococcus gallolyticus strain FDAARGOS_755     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1997983..2008657
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC63_RS09990 (FOC63_09990) deoC 1998412..1999074 (-) 663 WP_009854243.1 deoxyribose-phosphate aldolase -
  FOC63_RS09995 (FOC63_09995) - 1999564..2000157 (-) 594 WP_009854244.1 class I SAM-dependent methyltransferase -
  FOC63_RS10000 (FOC63_10000) coaA 2000271..2001191 (+) 921 WP_009854245.1 type I pantothenate kinase -
  FOC63_RS10005 (FOC63_10005) rpsT 2001266..2001517 (+) 252 WP_003064878.1 30S ribosomal protein S20 -
  FOC63_RS10010 (FOC63_10010) ciaH 2001653..2002993 (-) 1341 WP_009854246.1 sensor histidine kinase Regulator
  FOC63_RS10015 (FOC63_10015) ciaR 2002983..2003657 (-) 675 WP_009854247.1 response regulator transcription factor Regulator
  FOC63_RS10020 (FOC63_10020) - 2003855..2006398 (-) 2544 WP_009854248.1 M1 family metallopeptidase -
  FOC63_RS10025 (FOC63_10025) phoU 2006621..2007274 (-) 654 WP_009854249.1 phosphate signaling complex protein PhoU -
  FOC63_RS10030 (FOC63_10030) pstB 2007305..2008063 (-) 759 WP_009854250.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25465.13 Da        Isoelectric Point: 4.3102

>NTDB_id=450172 FOC63_RS10015 WP_009854247.1 2002983..2003657(-) (ciaR) [Streptococcus gallolyticus strain FDAARGOS_755]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKDGFQVLKELREKGVSTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKYNDNTLSYEELTVDTSTNTTIANGKEVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFAKNLQTLRSVGYILKNAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=450172 FOC63_RS10015 WP_009854247.1 2002983..2003657(-) (ciaR) [Streptococcus gallolyticus strain FDAARGOS_755]
ATGATTAAGATATTATTAGTAGAAGATGATTTGAGTCTATCTAATTCCATTTTTGATTTTTTAGATGATTTTGCAGATGT
TATGCAGGTATTTGACGGCGAAGAAGGTTTGTACGAAGCTGAAAGTGGCGTATATGACCTTATTTTGCTTGACTTGATGT
TACCTGAAAAAGATGGTTTCCAAGTGCTTAAAGAGTTACGAGAAAAAGGTGTGTCAACACCAGTACTTATTATGACTGCC
AAAGAAAGCCTTGATGATAAGGGACATGGTTTCGAGTTGGGAGCAGATGATTACCTTACTAAACCATTTTACCTTGAAGA
GCTAAAAATGCGTATTCAAGCTCTTTTAAAACGTTCGGGTAAATACAACGACAATACCTTATCTTATGAAGAATTAACCG
TTGACACTTCTACCAATACAACAATAGCTAACGGTAAAGAAGTCGAGCTGCTTGGTAAAGAATTTGATTTGTTGGTTTAT
TTCTTACAAAATCAAAATGTTATTTTACCAAAATCACAAATTTTTGACCGTATTTGGGGCTTTGATAGTGATACAACGAT
TTCGGTTGTTGAAGTTTACGTTTCAAAAATTCGAAAAAAACTCAAAGGCACTACCTTTGCCAAAAATCTTCAAACCCTAC
GGAGTGTAGGTTATATTCTGAAAAATGCTGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139MP14

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

92.825

99.554

0.924
  ciaR Streptococcus pneumoniae Rx1

87.054

100

0.871
  ciaR Streptococcus pneumoniae D39

87.054

100

0.871
  ciaR Streptococcus pneumoniae R6

87.054

100

0.871
  ciaR Streptococcus pneumoniae TIGR4

87.054

100

0.871
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.938

100

0.393
  vicR Streptococcus mutans UA159

35.47

100

0.371
  micA Streptococcus pneumoniae Cp1015

35.622

100

0.371