Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   FOC71_RS07080 Genome accession   NZ_CP053999
Coordinates   1401589..1402293 (-) Length   234 a.a.
NCBI ID   WP_117275325.1    Uniprot ID   -
Organism   Streptococcus intermedius strain FDAARGOS_769     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1396589..1407293
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC71_RS07065 (FOC71_07065) - 1397153..1398139 (-) 987 WP_003072600.1 Gfo/Idh/MocA family protein -
  FOC71_RS07070 (FOC71_07070) - 1398579..1399292 (-) 714 WP_003072599.1 DUF805 domain-containing protein -
  FOC71_RS07075 (FOC71_07075) - 1399370..1401605 (-) 2236 Protein_1373 DNA internalization-related competence protein ComEC/Rec2 -
  FOC71_RS07080 (FOC71_07080) comEA/celA/cilE 1401589..1402293 (-) 705 WP_117275325.1 helix-hairpin-helix domain-containing protein Machinery gene
  FOC71_RS07085 (FOC71_07085) smpB 1402461..1402928 (-) 468 WP_003072592.1 SsrA-binding protein SmpB -
  FOC71_RS07090 (FOC71_07090) rnr 1402891..1405230 (-) 2340 WP_003072590.1 ribonuclease R -
  FOC71_RS07095 (FOC71_07095) secG 1405321..1405554 (-) 234 WP_003024744.1 preprotein translocase subunit SecG -
  FOC71_RS07100 (FOC71_07100) rpmG 1405594..1405743 (-) 150 WP_003034401.1 50S ribosomal protein L33 -
  FOC71_RS07105 (FOC71_07105) - 1405727..1406944 (-) 1218 WP_302051832.1 multidrug efflux MFS transporter -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 25413.96 Da        Isoelectric Point: 9.7605

>NTDB_id=450026 FOC71_RS07080 WP_117275325.1 1401589..1402293(-) (comEA/celA/cilE) [Streptococcus intermedius strain FDAARGOS_769]
MLEVIVAKIKEYKILVALSLIGLIIAGFFMMTSKSARQSNVGDIAQEITNAKLERKETSTETKKKQQKEETKSQKNLASE
ELEFLTVDVKGAVKNPGIYQLKKTSRINDAIQKAGGLTTDADSKSINLAQKLTDEAVIYVAAMGENVTNVASNNGQTLTK
DTNGTAVQKGNKVNLNKANLSDLQSISGIGQKRAQDILDYREANGKFNSVDDLKNVSGVGAKTLEKLKEYVTVD

Nucleotide


Download         Length: 705 bp        

>NTDB_id=450026 FOC71_RS07080 WP_117275325.1 1401589..1402293(-) (comEA/celA/cilE) [Streptococcus intermedius strain FDAARGOS_769]
ATGTTAGAGGTAATCGTCGCAAAAATCAAAGAGTATAAAATTTTAGTTGCTTTAAGCCTGATTGGTTTGATCATAGCAGG
ATTTTTTATGATGACTAGTAAATCTGCTAGACAATCTAATGTGGGAGATATTGCACAAGAGATCACAAATGCAAAACTAG
AACGGAAAGAAACTTCAACTGAAACGAAGAAAAAACAACAGAAAGAAGAAACAAAATCTCAAAAGAATTTAGCGAGTGAA
GAATTGGAATTTTTAACTGTAGATGTTAAAGGTGCTGTTAAAAATCCAGGTATTTATCAATTAAAAAAAACGAGCCGAAT
CAATGATGCTATCCAAAAAGCGGGTGGACTAACAACAGACGCTGACAGCAAATCTATCAATTTGGCTCAAAAACTAACAG
ACGAGGCTGTGATTTATGTGGCAGCTATGGGTGAAAATGTAACAAATGTTGCAAGTAATAATGGACAAACTTTAACGAAA
GATACCAATGGAACTGCGGTACAAAAAGGGAATAAGGTCAATCTAAATAAGGCTAATTTGTCTGATTTACAGTCTATTTC
TGGTATCGGACAAAAGCGCGCCCAAGATATTTTAGATTATCGTGAGGCAAATGGAAAATTTAATTCTGTTGATGATCTTA
AAAATGTATCAGGAGTTGGTGCTAAAACATTAGAGAAATTGAAAGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(169-232)

SLBB domain (SLBB)

(87-140)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis SK321

49.789

100

0.504
  comEA/celA/cilE Streptococcus mitis NCTC 12261

49.785

99.573

0.496
  comEA/celA/cilE Streptococcus pneumoniae D39

49.356

99.573

0.491
  comEA/celA/cilE Streptococcus pneumoniae R6

49.356

99.573

0.491
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

49.356

99.573

0.491
  comEA/celA/cilE Streptococcus pneumoniae Rx1

49.356

99.573

0.491
  comEA Streptococcus thermophilus LMD-9

43.162

100

0.432
  comEA Lactococcus lactis subsp. cremoris KW2

38.627

99.573

0.385