Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FOC71_RS06355 Genome accession   NZ_CP053999
Coordinates   1260424..1261098 (+) Length   224 a.a.
NCBI ID   WP_003036714.1    Uniprot ID   -
Organism   Streptococcus intermedius strain FDAARGOS_769     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1255424..1266098
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC71_RS06325 (FOC71_06325) - 1256980..1257939 (+) 960 WP_003072868.1 ROK family glucokinase -
  FOC71_RS06330 (FOC71_06330) rplS 1258089..1258436 (+) 348 WP_003072867.1 50S ribosomal protein L19 -
  FOC71_RS06340 (FOC71_06340) - 1258681..1258896 (+) 216 WP_003072866.1 hypothetical protein -
  FOC71_RS09845 - 1259055..1259420 (+) 366 WP_003072864.1 hypothetical protein -
  FOC71_RS06350 (FOC71_06350) - 1259719..1260162 (+) 444 WP_003072862.1 hypothetical protein -
  FOC71_RS06355 (FOC71_06355) ciaR 1260424..1261098 (+) 675 WP_003036714.1 response regulator transcription factor Regulator
  FOC71_RS06360 (FOC71_06360) ciaH 1261088..1262434 (+) 1347 WP_003072859.1 cell wall metabolism sensor histidine kinase WalK Regulator
  FOC71_RS06365 (FOC71_06365) - 1262710..1264158 (-) 1449 WP_003072857.1 alpha-amylase -
  FOC71_RS06370 (FOC71_06370) - 1264528..1265037 (-) 510 WP_003072855.1 DNA topology modulation protein -
  FOC71_RS06375 (FOC71_06375) rpsT 1265102..1265338 (-) 237 WP_003072853.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25373.03 Da        Isoelectric Point: 4.2408

>NTDB_id=450023 FOC71_RS06355 WP_003036714.1 1260424..1261098(+) (ciaR) [Streptococcus intermedius strain FDAARGOS_769]
MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLIMTA
KESLNDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNENTLSYGDVTINLSTNTTLVDGNEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTTFANNLQTLRSVGYILKDAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=450023 FOC71_RS06355 WP_003036714.1 1260424..1261098(+) (ciaR) [Streptococcus intermedius strain FDAARGOS_769]
ATGATTAAGATTCTATTAGTAGAAGATGACCTCGGTTTATCTAACTCAGTATTTGATTTTTTAGATGACTTTGCAGATGT
CATGCAAGTTTTTGATGGTGAGGAAGGATTGTACGAAGCTGAAAGTGGTGTGTATGATCTTATCTTACTTGATTTGATGT
TACCGGAAAAAGATGGTTTTCAAGTATTGAAGGAATTACGTGAAAAAGGTGTTACAACACCGGTATTGATTATGACAGCT
AAAGAGAGTTTGAATGATAAAGGACATGGTTTTGAGCTGGGAGCTGACGATTATTTGACCAAACCATTTTATTTGGAAGA
GTTAAAAATGCGGATTCAAGCTCTTTTGAAACGATCGGGCAAGTTTAATGAAAATACTCTTTCTTATGGTGATGTAACCA
TTAATTTGTCAACGAACACTACACTTGTAGATGGAAATGAAGTAGAGTTACTCGGAAAAGAATTTGATTTATTAGTATAT
TTCTTGCAGAATCAAAATGTTATTCTACCGAAGACGCAGATTTTCGATCGCTTATGGGGGTTTGATAGTGATACAACCAT
TTCAGTTGTAGAAGTTTATGTCTCAAAAATTCGGAAAAAATTGAAAGGGACGACCTTTGCGAACAACCTTCAAACGCTTC
GCAGCGTCGGATATATTTTAAAAGATGCTGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

91.518

100

0.915
  ciaR Streptococcus pneumoniae D39

91.518

100

0.915
  ciaR Streptococcus pneumoniae R6

91.518

100

0.915
  ciaR Streptococcus pneumoniae TIGR4

91.518

100

0.915
  ciaR Streptococcus mutans UA159

89.686

99.554

0.893
  covR Lactococcus lactis subsp. lactis strain DGCC12653

39.207

100

0.397
  vicR Streptococcus mutans UA159

36.481

100

0.379
  covR Streptococcus salivarius strain HSISS4

35.683

100

0.362