Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   FOC71_RS05985 Genome accession   NZ_CP053999
Coordinates   1181971..1182672 (+) Length   233 a.a.
NCBI ID   WP_003072980.1    Uniprot ID   A0A3R9KV56
Organism   Streptococcus intermedius strain FDAARGOS_769     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1176971..1187672
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC71_RS05965 (FOC71_05965) ccpA 1177895..1178899 (+) 1005 WP_003072985.1 catabolite control protein A Regulator
  FOC71_RS05970 (FOC71_05970) - 1178992..1179990 (+) 999 WP_003072984.1 glycosyltransferase family 4 protein -
  FOC71_RS05975 (FOC71_05975) - 1179992..1181305 (+) 1314 WP_003072983.1 glycosyltransferase family 4 protein -
  FOC71_RS05980 (FOC71_05980) - 1181332..1181673 (+) 342 WP_003072981.1 hypothetical protein -
  FOC71_RS05985 (FOC71_05985) micA 1181971..1182672 (+) 702 WP_003072980.1 response regulator YycF Regulator
  FOC71_RS05990 (FOC71_05990) micB 1182665..1184017 (+) 1353 WP_003072979.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FOC71_RS05995 (FOC71_05995) vicX 1184019..1184822 (+) 804 WP_003072978.1 MBL fold metallo-hydrolase Regulator
  FOC71_RS06000 (FOC71_06000) - 1184831..1185190 (+) 360 WP_003072977.1 YbaN family protein -
  FOC71_RS06005 (FOC71_06005) rnc 1185580..1186278 (+) 699 WP_003072976.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26851.80 Da        Isoelectric Point: 4.6824

>NTDB_id=450019 FOC71_RS05985 WP_003072980.1 1181971..1182672(+) (micA) [Streptococcus intermedius strain FDAARGOS_769]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALELFEAERPDILILDLMLPEIDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAAPTEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=450019 FOC71_RS05985 WP_003072980.1 1181971..1182672(+) (micA) [Streptococcus intermedius strain FDAARGOS_769]
ATGAAAAAAATATTAGTTGTAGATGATGAAAAACCAATCTCAGATATCATAAAATTTAACATGGTAAAAGAAGGTTATGA
GGTAGTGACAGCCTTCGATGGTCGTGAAGCGTTAGAGCTGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGATTTGA
TGTTGCCTGAAATAGATGGCTTAGAGGTAGCGCGAACGATTCGGAAAACGAGCAATGTACCAATCATCGTTCTGTCTGCT
AAAGATAGCGAATTTGATAAAGTCATTGGTCTCGAAATTGGCGCAGATGATTATATGACAAAGCCGTTTTCTAATCGTGA
GTTACAGGCGCGTGTCAAAGCTATTTTACGTCGTACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCCAACAG
AAATTGTGATTGGAGATTTGCAGATTTTGACGGATGCTTTTGTTGTGAAAAAGCATGGTGAAGAATTGGATTTAACACAC
CGTGAATTTGAATTACTACACCACCTAGCTACACATATTGGTCAAGTGATGACGCGTGAACACCTACTAGAAACAGTATG
GGGTTATGATTATTTTGGAGATGTGCGGACTGTTGATGTAACGATTCGCCGTTTGAGGGAAAAAATTGAAGATATTCCTA
GCCGCCCAGAGTATATTTTAACACGGCGTGGTGTTGGATATTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3R9KV56

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

83.262

100

0.833
  vicR Streptococcus mutans UA159

79.237

100

0.803
  covR Streptococcus salivarius strain HSISS4

44.348

98.712

0.438
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.541

98.283

0.438
  scnR Streptococcus mutans UA159

36.052

100

0.361