Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   FOC71_RS05990 Genome accession   NZ_CP053999
Coordinates   1182665..1184017 (+) Length   450 a.a.
NCBI ID   WP_003072979.1    Uniprot ID   -
Organism   Streptococcus intermedius strain FDAARGOS_769     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1177665..1189017
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC71_RS05965 (FOC71_05965) ccpA 1177895..1178899 (+) 1005 WP_003072985.1 catabolite control protein A Regulator
  FOC71_RS05970 (FOC71_05970) - 1178992..1179990 (+) 999 WP_003072984.1 glycosyltransferase family 4 protein -
  FOC71_RS05975 (FOC71_05975) - 1179992..1181305 (+) 1314 WP_003072983.1 glycosyltransferase family 4 protein -
  FOC71_RS05980 (FOC71_05980) - 1181332..1181673 (+) 342 WP_003072981.1 hypothetical protein -
  FOC71_RS05985 (FOC71_05985) micA 1181971..1182672 (+) 702 WP_003072980.1 response regulator YycF Regulator
  FOC71_RS05990 (FOC71_05990) micB 1182665..1184017 (+) 1353 WP_003072979.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FOC71_RS05995 (FOC71_05995) vicX 1184019..1184822 (+) 804 WP_003072978.1 MBL fold metallo-hydrolase Regulator
  FOC71_RS06000 (FOC71_06000) - 1184831..1185190 (+) 360 WP_003072977.1 YbaN family protein -
  FOC71_RS06005 (FOC71_06005) rnc 1185580..1186278 (+) 699 WP_003072976.1 ribonuclease III -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51225.43 Da        Isoelectric Point: 4.7207

>NTDB_id=450020 FOC71_RS05990 WP_003072979.1 1182665..1184017(+) (micB) [Streptococcus intermedius strain FDAARGOS_769]
MIDNIRQFVVSKDFVFVLLILGFILVITLLSLENRRDNVRIRQLNQKVKDLIAGDYSEVLDMQGGPEITDITNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIIMINDMATKQLGVKESDARKMNILKLLGIEDEYDLRDLITKVPE
LTIDSQDENGEFLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVSDLLSLSRIDNATSHLDIELTNFTAFITFILNRFDKIRSQNDDKKYEIIRDYPINSTW
VEIDTDKMTQVIDNIINNAIKYSPDGGKITVSMKTTETQMILSISDEGLGIPKKDLPKIFDRFYRVDKARSRAQGGSGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKEAVKDDDWEEDGLEG

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=450020 FOC71_RS05990 WP_003072979.1 1182665..1184017(+) (micB) [Streptococcus intermedius strain FDAARGOS_769]
ATGATTGATAATATAAGACAATTTGTTGTATCAAAAGATTTTGTATTTGTCCTACTCATTTTAGGATTTATTTTGGTCAT
TACGTTGCTGTCCTTGGAAAATCGACGTGATAATGTTCGTATTCGCCAATTGAATCAAAAAGTGAAAGACTTAATTGCGG
GAGATTATTCAGAAGTTTTAGATATGCAAGGTGGTCCAGAAATCACTGATATTACCAATAGTATCAATGATTTATCTGAA
GTGATTCGCTTAACGCATGAAAACTTAGAACAAGAAACTAAGCGGTTATCGAGTATTTTATCCTACATGACGGACGGTGT
CCTTGCGACCAATCGTCGTGGGCAAATTATCATGATTAATGATATGGCGACCAAGCAGTTGGGAGTCAAGGAATCTGATG
CACGAAAGATGAATATCTTAAAACTGTTAGGGATTGAAGATGAATATGATTTACGGGACTTGATTACGAAAGTTCCAGAG
CTGACCATTGATTCACAGGATGAAAATGGAGAATTTTTAAGCTTGCGTGTTCGCTTTGCCTTGATTCGTCGAGAGTCAGG
CTTTATTTCTGGGTTGGTTGCAGTGTTGCATGATACAACGGAGCAGGAAAAAGAGGAACGTGAGCGGAGACTATTTGTTT
CTAATGTCAGTCATGAATTGCGTACTCCCTTGACCAGTGTCAAGTCTTATCTGGAAGCATTAGATGAAGGCGCTTTGTCT
GAGCCGGTTGCACCAGATTTCATCAAGGTTTCGTTAGATGAAACCAATCGGATGATGCGAATGGTTTCGGACTTACTGAG
TTTGTCGCGGATTGATAATGCGACTAGCCATTTGGATATTGAACTGACAAATTTTACAGCTTTCATCACATTTATTTTGA
ATCGTTTTGACAAGATTAGAAGTCAGAACGATGATAAAAAGTACGAAATTATCCGAGATTATCCAATTAATTCTACTTGG
GTCGAAATTGATACAGATAAAATGACACAAGTTATTGATAATATTATCAATAATGCCATTAAATATTCTCCTGATGGTGG
TAAGATTACGGTGAGTATGAAAACAACTGAGACCCAAATGATTTTATCTATATCAGATGAAGGTTTAGGAATTCCCAAAA
AAGATTTACCAAAAATTTTTGATCGATTTTATCGTGTAGACAAAGCGAGAAGTCGTGCACAAGGTGGATCGGGACTGGGC
TTGGCCATTGCTAAAGAAATTATCAAGCAGCATAACGGTTTTATCTGGGCGAAGAGTGAATATGGTAAAGGATCGACATT
TACAATCGTTCTGCCTTATGACAAAGAAGCTGTCAAAGATGATGATTGGGAAGAAGATGGATTAGAAGGATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(95-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

81.549

97.556

0.796
  vicK Streptococcus mutans UA159

71.149

90.889

0.647