Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   ST90729_RS07995 Genome accession   NZ_CP065480
Coordinates   1546194..1547561 (-) Length   455 a.a.
NCBI ID   WP_347116587.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 90729     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1541194..1552561
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST90729_RS07960 (ST90729_07940) - 1541544..1541810 (-) 267 WP_211836860.1 Blp family class II bacteriocin -
  ST90729_RS07965 - 1542061..1542462 (-) 402 WP_011226490.1 hypothetical protein -
  ST90729_RS07970 (ST90729_07945) - 1542792..1542959 (-) 168 WP_011226492.1 hypothetical protein -
  ST90729_RS07975 (ST90729_07950) - 1543449..1543679 (-) 231 WP_011226494.1 bacteriocin class II family protein -
  ST90729_RS07980 (ST90729_07955) comE/blpR 1543929..1544660 (+) 732 WP_347116585.1 LytTR family DNA-binding domain-containing protein Regulator
  ST90729_RS07985 comD/blpH 1545197..1546000 (+) 804 WP_347116586.1 ATP-binding protein Regulator
  ST90729_RS07990 (ST90729_07965) - 1546018..1546179 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  ST90729_RS07995 (ST90729_07970) comB 1546194..1547561 (-) 1368 WP_347116587.1 bacteriocin secretion accessory protein Regulator
  ST90729_RS08000 (ST90729_07975) comA/nlmT 1547577..1549730 (-) 2154 WP_157769910.1 peptide cleavage/export ABC transporter Regulator
  ST90729_RS08005 (ST90729_07980) - 1550744..1552489 (-) 1746 WP_347116588.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 50368.09 Da        Isoelectric Point: 4.7492

>NTDB_id=447726 ST90729_RS07995 WP_347116587.1 1546194..1547561(-) (comB) [Streptococcus thermophilus strain 90729]
MNPQLFKSTEFYHRRYHNMSTVLITPLILLVIFLFLFAFFAKKEVTVTSRGSIEPTKVIAVIQSTSDNTIIDNQLVANKV
VKKGDTLVQYSETMEASQKEGLQKQLELLKRQESGLKTLQSSLTQGTNLFQEQEDEFGYQSTFNTYLSQAQDIDLGVAKT
NTEVNNQAAIASNTGSAIDNQISQLPTQVSEYEALSQAITNHETTLPEGNPHQATLNAYNSQYATTPDASVTDQYLSQVN
TNISSLNASIGNLEIQKAGTGTVVTYDNSDSTKKEALKNQFLQNAGQQLSSVETQITDTESKINQADVLLTNTLIQSPED
GILHLSQADKKATMAATGTELAQLYPDMTQTQEVAITYYVNSDYVPKLQKGQSVRLTLDKVGNHGTTIIGKLESIDNSAT
ETERGNVFRVTARASISEKEAQNLRYGLESRVTSVIDQKTYFNYFKDKLLNLQDQ

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=447726 ST90729_RS07995 WP_347116587.1 1546194..1547561(-) (comB) [Streptococcus thermophilus strain 90729]
ATGAATCCACAGTTGTTTAAAAGCACAGAGTTTTACCATCGTCGCTACCACAATATGTCTACTGTTTTGATTACTCCCTT
GATTTTGTTAGTTATTTTCCTTTTTCTTTTCGCTTTTTTTGCTAAGAAGGAAGTTACAGTCACGTCTAGAGGAAGTATAG
AGCCAACCAAGGTTATCGCAGTAATCCAATCAACCAGTGACAATACCATCATAGATAATCAACTGGTTGCTAATAAGGTT
GTTAAAAAAGGGGACACCTTAGTTCAGTATTCAGAGACCATGGAGGCATCGCAAAAAGAGGGGCTTCAAAAGCAACTAGA
ACTTTTAAAAAGACAGGAATCAGGTTTGAAGACCTTGCAATCTAGCCTAACGCAGGGAACCAATCTTTTCCAAGAACAGG
AAGACGAGTTTGGTTATCAGAGTACTTTTAACACCTACCTAAGTCAGGCACAGGATATTGACTTGGGTGTGGCTAAAACA
AATACAGAGGTTAATAACCAAGCAGCAATTGCGAGTAATACCGGTTCTGCTATTGATAACCAGATTAGTCAATTGCCGAC
TCAGGTCTCAGAGTATGAGGCGCTCTCTCAAGCTATTACCAATCATGAAACGACTTTACCTGAAGGCAATCCTCATCAGG
CAACCTTAAATGCCTATAACAGTCAGTATGCTACGACACCGGATGCCAGTGTAACAGACCAATACCTATCTCAAGTTAAT
ACCAATATTTCGAGCTTGAATGCTTCCATAGGTAATCTAGAAATCCAAAAGGCTGGGACAGGCACAGTTGTAACTTATGA
CAATAGTGATAGCACTAAAAAAGAAGCTCTAAAAAATCAATTCTTGCAAAATGCAGGACAGCAATTGAGCTCAGTGGAAA
CACAAATTACCGATACCGAGAGTAAAATCAATCAGGCAGATGTCCTTCTGACTAATACCCTCATCCAGTCACCAGAAGAT
GGAATCTTACACTTGAGTCAAGCTGATAAAAAAGCAACCATGGCTGCGACAGGAACTGAGTTGGCCCAGCTTTATCCCGA
TATGACTCAAACCCAGGAAGTTGCCATTACTTATTATGTGAATTCGGATTATGTGCCAAAACTGCAAAAAGGCCAGTCAG
TTCGACTGACCTTGGATAAGGTTGGTAATCACGGTACCACAATTATTGGAAAACTTGAGAGTATTGATAATTCTGCCACG
GAAACAGAAAGGGGGAATGTGTTTAGAGTAACTGCTAGGGCAAGTATTTCAGAAAAAGAAGCCCAAAATCTACGTTACGG
TCTAGAAAGTCGTGTGACAAGCGTTATTGACCAAAAGACCTACTTCAATTACTTTAAAGACAAGTTACTAAACTTGCAAG
ACCAATAG

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(315-427)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

39.246

99.121

0.389
  comB Streptococcus pneumoniae D39

39.246

99.121

0.389
  comB Streptococcus pneumoniae R6

39.246

99.121

0.389
  comB Streptococcus pneumoniae TIGR4

38.581

99.121

0.382
  comB Streptococcus mitis SK321

37.916

99.121

0.376
  comB Streptococcus mitis NCTC 12261

37.916

99.121

0.376