Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ST90729_RS07980 Genome accession   NZ_CP065480
Coordinates   1543929..1544660 (+) Length   243 a.a.
NCBI ID   WP_347116585.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 90729     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1538929..1549660
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST90729_RS07955 (ST90729_07935) - 1539828..1541398 (+) 1571 WP_347116584.1 IS3-like element ISSth1b family transposase -
  ST90729_RS07960 (ST90729_07940) - 1541544..1541810 (-) 267 WP_211836860.1 Blp family class II bacteriocin -
  ST90729_RS07965 - 1542061..1542462 (-) 402 WP_011226490.1 hypothetical protein -
  ST90729_RS07970 (ST90729_07945) - 1542792..1542959 (-) 168 WP_011226492.1 hypothetical protein -
  ST90729_RS07975 (ST90729_07950) - 1543449..1543679 (-) 231 WP_011226494.1 bacteriocin class II family protein -
  ST90729_RS07980 (ST90729_07955) comE/blpR 1543929..1544660 (+) 732 WP_347116585.1 LytTR family DNA-binding domain-containing protein Regulator
  ST90729_RS07985 comD/blpH 1545197..1546000 (+) 804 WP_347116586.1 ATP-binding protein Regulator
  ST90729_RS07990 (ST90729_07965) - 1546018..1546179 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  ST90729_RS07995 (ST90729_07970) comB 1546194..1547561 (-) 1368 WP_347116587.1 bacteriocin secretion accessory protein Regulator

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 27793.07 Da        Isoelectric Point: 6.9136

>NTDB_id=447724 ST90729_RS07980 WP_347116585.1 1543929..1544660(+) (comE/blpR) [Streptococcus thermophilus strain 90729]
MKIYLLEDNSIQMGRLEEAVAHELKSFGKDLSCVQSFDKPDQLLSAITSNTSDQIFFLDIEIKGEDKKGLDIAKIIRQNN
PYAIIAFVTTHIEFMPQAFGVTAYKYINKTLDEASFRKEIGETIAQVFPINATTTDEFFLYKTESQLINLPMDQILYLST
SDIKHHVHLQTIHTLMDIRANLADFKKIHKKLYSCHRSYIVNTDMIISVNKTNYEATLINGQVLPVSRMKIGKIAQIVEE
RGR

Nucleotide


Download         Length: 732 bp        

>NTDB_id=447724 ST90729_RS07980 WP_347116585.1 1543929..1544660(+) (comE/blpR) [Streptococcus thermophilus strain 90729]
TTGAAGATTTACCTATTAGAAGATAATTCTATTCAGATGGGTCGCTTGGAAGAGGCTGTGGCACATGAACTTAAATCCTT
CGGAAAAGATCTATCTTGTGTCCAGTCTTTTGACAAACCTGACCAGTTGTTATCAGCTATCACTTCTAATACAAGCGATC
AGATTTTCTTTCTTGATATTGAAATTAAAGGTGAAGATAAGAAGGGACTTGATATCGCTAAAATCATACGTCAAAATAAC
CCTTATGCTATCATTGCCTTTGTCACTACACATATAGAGTTCATGCCTCAAGCTTTTGGCGTTACAGCCTATAAATACAT
CAATAAAACCTTAGATGAAGCTAGCTTTAGAAAAGAAATAGGGGAAACCATTGCTCAAGTCTTCCCTATTAACGCAACTA
CCACGGATGAGTTTTTTCTCTACAAAACAGAGTCTCAATTAATAAACCTTCCTATGGATCAAATTCTATACCTATCCACA
TCAGATATCAAACACCATGTTCACCTCCAGACTATCCATACCCTCATGGATATCCGAGCAAATCTGGCAGACTTTAAAAA
GATACACAAAAAGCTCTACTCATGCCATCGGTCCTATATCGTCAATACAGATATGATCATCTCTGTCAACAAGACCAATT
ATGAAGCTACCTTAATTAATGGTCAAGTTCTACCAGTATCCCGTATGAAGATAGGAAAGATTGCACAGATTGTTGAGGAA
AGAGGCAGATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(146-237)

Response regulator receiver domain (Response_reg)

(17-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

35.628

100

0.362